製品名:Methyl 2-azaadamantane-5-carboxylate hydrochloride

IUPAC Name:methyl 2-azatricyclo[3.3.1.1³,⁷]decane-5-carboxylate hydrochloride

CAS番号:1389264-13-4
分子式:C11H18ClNO2
純度:97%
カタログ番号:CM106771
分子量:231.72

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製品詳細

CAS番号:1389264-13-4
分子式:C11H18ClNO2
融点:-
SMILESコード:O=C(C12CC3NC(C2)CC(C3)C1)OC.[H]Cl
密度:
カタログ番号:CM106771
分子量:231.72
沸点:
MDL番号:
保管方法:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Bridged Compounds
Bridged ring compound refers to any two rings in the compound, which share two non-directly connected carbon atoms, and are classified into bicyclic hydrocarbons, tricyclic hydrocarbons, tetracyclic hydrocarbons, etc. Carbon atoms used in two or more rings are bridgehead carbon atoms, and the bond connecting the bridgehead carbon atoms is called a bridge. Bridged ring compounds are a class of organic compounds that are widely present in nature and usually have important physiological activities, such as the famous anticancer drug paclitaxel and antimalarial drug artemisinin.
bridged compounds,bridged bicyclic compounds
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Cyclohexanes
Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.

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Product Other Information

Product Overview Methyl 2-azaadamantane-5-carboxylate hydrochloride, also known as memantine hydrochloride, is a synthetic drug that is used to treat Alzheimer's disease. It is a derivative of amantadine, a drug that was originally developed to treat influenza. Memantine hydrochloride is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist that is used to slow down the progression of Alzheimer's disease.
Synthesis and Application Memantine hydrochloride is synthesized from 1-amino-3,5-dimethyladamantane, which is a derivative of amantadine. The synthesis involves the reaction of 1-amino-3,5-dimethyladamantane with methyl chloroformate to form methyl 1-amino-3,5-dimethyladamantane-2-carboxylate. This compound is then reacted with hydrochloric acid to form Methyl 2-azaadamantane-5-carboxylate hydrochloride hydrochloride. Memantine hydrochloride has been extensively studied for its potential therapeutic effects on Alzheimer's disease. It has been shown to improve cognitive function and reduce behavioral symptoms in patients with Alzheimer's disease. Memantine hydrochloride has also been studied for its potential therapeutic effects on other neurodegenerative disorders, such as Parkinson's disease and Huntington's disease.
Future Directions There are a number of future directions for research on Methyl 2-azaadamantane-5-carboxylate hydrochloride hydrochloride. One area of research is the development of more selective NMDA receptor antagonists that can target specific subtypes of the receptor. Another area of research is the development of combination therapies that can target multiple pathways involved in Alzheimer's disease. Finally, there is a need for more research on the long-term effects of Methyl 2-azaadamantane-5-carboxylate hydrochloride hydrochloride on cognitive function and quality of life in patients with Alzheimer's disease.