製品名:Methyl 2-azaadamantane-5-carboxylate hydrochloride
IUPAC Name:methyl 2-azatricyclo[3.3.1.1³,⁷]decane-5-carboxylate hydrochloride
Product Overview |
Methyl 2-azaadamantane-5-carboxylate hydrochloride, also known as memantine hydrochloride, is a synthetic drug that is used to treat Alzheimer's disease. It is a derivative of amantadine, a drug that was originally developed to treat influenza. Memantine hydrochloride is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist that is used to slow down the progression of Alzheimer's disease. |
Synthesis and Application |
Memantine hydrochloride is synthesized from 1-amino-3,5-dimethyladamantane, which is a derivative of amantadine. The synthesis involves the reaction of 1-amino-3,5-dimethyladamantane with methyl chloroformate to form methyl 1-amino-3,5-dimethyladamantane-2-carboxylate. This compound is then reacted with hydrochloric acid to form Methyl 2-azaadamantane-5-carboxylate hydrochloride hydrochloride. Memantine hydrochloride has been extensively studied for its potential therapeutic effects on Alzheimer's disease. It has been shown to improve cognitive function and reduce behavioral symptoms in patients with Alzheimer's disease. Memantine hydrochloride has also been studied for its potential therapeutic effects on other neurodegenerative disorders, such as Parkinson's disease and Huntington's disease. |
Future Directions |
There are a number of future directions for research on Methyl 2-azaadamantane-5-carboxylate hydrochloride hydrochloride. One area of research is the development of more selective NMDA receptor antagonists that can target specific subtypes of the receptor. Another area of research is the development of combination therapies that can target multiple pathways involved in Alzheimer's disease. Finally, there is a need for more research on the long-term effects of Methyl 2-azaadamantane-5-carboxylate hydrochloride hydrochloride on cognitive function and quality of life in patients with Alzheimer's disease. |