APPROVAL DRUGS
(2017-2022)
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Sodium ilaprazole | 壹丽安 | Proton pump | Peptic ulcer | Livzon Pharmaceutical Group Inc. |
| Eltrombopag Diolamine | 瑞弗兰 | TpoR | Idiopathic thrombocytopenic purpura | Novartis Pharma Schweiz Ag |
| Modafinil | 伟大 | DAT | Somnolence Hypersomnolence | Welman Phamaceutical |
| Vortioxetine Hydrobromide | 心达悦 | 5-HT1A 5-HT1B 5-HT1D 5-HT3 5-HT7 SERT | Major depressive disorder | Lundbeck Pharmaceutical |
| Diquafosol Tetrasodium | 丽爱思 | P2RY2 | Xerophthalmia | Santen Pharmaceutical Co Ltd |
| Lixisenatide | 利时敏 | GLP1R | Type 2 diabetes mellitus | Sanofi-Aventis Groupe |
| Mirabegron | 贝坦利 | ADRB3 | Overactive bladder | Astellas Pharma Europe Bv |
| Canagliflozin Hemihydrate | 怡可安 | SGLT2 | Type 2 diabetes mellitus | Jassen-Cilag International Nv |
| Macitentan | 傲朴舒 | ETAR ETBR | Pulmonary arterial hypertension | Actelion Pharmaceuticals Ltd |
| Dasabuvir Sodium Hydrate | 易奇瑞 | NS5B | Chronic hepatitis C | Abbvie Ag |
| Sofosbuvir | 索华迪 | NS5B | Chronic hepatitis C | Gilead Sciences Inc |
| Riociguat | 安吉奥 | sGC | Pulmonary arterial hypertension | Bayer Healthcare Pharmaceuticals |
| Empagliflozin | 欧唐静 | SGLT2 | Type 2 diabetes mellitus | Boehringer Ingelheim International Gmbh |
| Nintedanib Esylate | 维加特 | FGFR1 FGFR2 FGFR3 FLT3 PDGFR-α PDGFR-β VEGFR1 VEGFR2 VEGFR3 | Idiopathic pulmonary fibrosis | Boehringer Ingelheim International Gmbh |
| Amisulpride | 索里昂 | DRD2 DRD3 | Schizophrenia | Sanofi-Aventis France Sa |
| Simeprevir Sodium | 奥莱森 | NS3/NS4A | Hepatitis C | Jassen-Cilag International Nv |
| Ibrutinib | 亿珂 | BTK | Chronic lymphocytic leukemia Mantle cell lymphoma | Pharmacyclics Llc |
| Rasagiline Mesylate | 安齐来 | MAOB | Parkinson’s disease | Teva Pharmaceutical |
| Asunaprevir | 速维普 | NS3/NS4A | Hepatitis C | Bristol-Myers Squibb (Singapore) Pte Ltd |
| Daclatasvir Dihydrochloride | 百立泽 | NS5A | Hepatitis C | Bristol-Myers Squibb (Singapore) Pte Ltd |
| Sugammadex Sodium | 布瑞亭 | Unidentified | Neuromuscular blockade reversal | Merck Sharp & Dohme Ltd |
| Azacitidine | 维达莎 | DNMT1 | Chronic myelocytic leukaemia Myelodysplastic syndrome Acute myelocytic leukemia | Celgene Europe Bv |
| Osimertinib Mesylate | 泰瑞沙 | EGFR | Non-small cell lung cancer | Astrazeneca Ab |
| Regorafenib Monohydrate | 拜万戈 | ABL1 B-raf C-Raf CSF1R DDR2 EphA2 FGFR1 FGFR2 KIT PDGFR-α PDGFR-β RET TIE2 TRKA VEGFR1 VEGFR2 VEGFR3 | Hepatocellular carcinoma Colorectal carcinoma | Bayer Pharma Ag |
| Vemurafenib | 佐博伏 | B-raf | Melanoma | Roche Registration Gmbh |
| Dapagliflozin Propanediol Monohydrate | 安达唐 | AMPK PGY1 SGLT2 | Type 2 diabetes mellitus | Astrazeneca Ab |
| Ruxolitinib Phosphate | 捷恪卫 | JAK1 JAK2 | Myelofibrosis Essential thrombocythemia Polycythemia vera | Novartis Europharm Ltd |
| Blonanserin | 洛珊 | 5-HT2A DRD2 | Schizophrenia | Sumitomo Dainippon Pharma Co Ltd |
| Afatinib Dimaleate | 吉泰瑞 | EGFR HER2 HER4 | Non-small cell lung cancer | Boehringer Ingelheim International Gmbh |
| Pazopanib Hydrochloride | 维全特 | B-raf CSF1R FGFR1 FGFR3 ITK KIT LCK PDGFR-α PDGFR-β VEGFR1 VEGFR2 VEGFR3 | Renal cell carcinoma | Novartis Pharma Schweiz Ag |
| Edoxaban Tosilate Hydrate | 里先安 | F10 | Venous thromboembolism Pulmonary embolism | Daiichi Sankyo Europe Gmbh |
| Roxadustat | 爱瑞卓 | HIF-PHs | Anemia | FibroGen |
| Bendamustine Hydrochloride | 存达 | DNA | B-cell lymphoma | Cephalon Inc |
| Selexipag | 优拓比 | PTGIR | Pulmonary arterial hypertension | Actelion Pharmaceuticals Ltd |
| Plerixafor | 释倍灵 | CXCR4 | Multiple myeloma Non-Hodgkin’s lymphoma | Genzyme Europe Bv |
| Lacosamide | 维派特 | NMDAR SCNA | Epilepsy | Ucb Pharma Sa |
| Olodaterol Hydrochloride | ADRB2 | Chronic obstructive pulmonary disease | Boehringer Ingelheim International Gmbh | |
| Degarelix Acetate | GnRHR | Prostatic cancer | Ferring Pharmaceuticals A/S | |
| Fruquintinib | 爱优特 英文：Elunate 爱优特/Elunate | VEGFR1 VEGFR2 VEGFR3 | Colorectal carcinoma | HUTCHMED |
| Flutrimazole | CYP51A1 | Fungal infection | Jiangsu Farever Pharma Co., Ltd | |
| Febuxostat | XO | Gout Hyperuricemia | Teijin Pharma | |
| Lenvatinib Mesylate | 乐卫玛 | FGFR1 FGFR2 FGFR3 FGFR4 KIT PDGFR-α RET VEGFR1 VEGFR2 VEGFR3 | Hepatocellular carcinoma | Eisai Europe Ltd |
| Olaparib | 利普卓 | PARP-2 PARP-3 PARP1 | Ovarian cancer | Astrazeneca Ab |
| Pyrotinib Maleate | 艾瑞妮 | EGFR HER2 HER4 | Breast cancer | Jiangsu Hengrui Pharmaceuticals Co.,Ltd |
| Alectinib Hydrochloride | 安圣莎 | ALK RET | Lung cancer | Roche Registration Gmbh |
| Perflubutane | 示卓安 | Unidentified | Contrast agent | Ge Healthcare As |
| Palbociclib | 爱博新 | CDK4 CDK6 | Breast cancer | Pfizer Europe Ma Eeig |
| Teriflunomide | 奥巴捷 | DHODH | Multiple sclerosis | Sanofi Us Services Inc |
| Danoprevir Sodium | 戈诺卫 | NS3/NS4A | Hepatitis C | Ascletis Pharma Inc. |
| Rotigotine | 优普洛 | DRD2 DRD3 | Parkinson's disease Restless legs syndrome | Ucb Pharma Sa |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Golimumab | 欣普尼 | TNFα | Ankylosing spondylitis Rheumatoid arthritis | Janssen Biologics Bv |
| Insulin degludec | 诺和达 | INSR GLP1R | Type 2 diabetes mellitus | Novo Nordisk |
| Omalizumab | 茁乐 | IgE | Asthma | Novartis Europharm Ltd |
| Recombinant Teriparatide（Shanghai United Cell ） | 珍固 | PTHR | Osteoporosis | Shanghai United Cell Biotechnology Co., Ltd. |
| Sintilimab | 达伯舒 | PD-1 | Hodgkin’s disease | Innovent Biologics Inc. |
| Pertuzumab | 帕捷特 | HER2 | Breast cancer | Roche Pharma (Schweiz) Ag |
| Toripalimab | 拓益 | PD-1 | Melanoma | Shanghai Junshi Biosciences Co., Ltd. |
| Emicizumab | 舒友立乐 | F10 F9 | Hemophilia A | Roche |
| Eculizumab | 舒立瑞 | C5 | Paroxysmal nocturnal hemoglobinuria Atypical hemolytic uremic syndrome | Alexion Europe Sas |
| Evolocumab | 瑞百安 | PCSK9 | Atherosclerosis Homozygous familial hypercholesterolemia | Amgen |
| Pembrolizumab | 可瑞达 | PD-1 | Melanoma Colorectal cancer Hepatocellular cancer Non-smallcell lung cancer | Merck |
| Peginterferon SA (Beijing Kawin Technology) | 派益生 | IFNAR | Hepatitis C | Beijing Kawin Technology Share-Holding Co., Ltd. |
| Nivolumab | 欧狄沃 | PD-1 | Non-small cell lung cancer | Bristol-Myers Squibb Pharma Eeig |
| Idarucizumab | 泰毕安 | PT | Hemorrhage | Boehringer Ingelheim International Gmbh |
| Recombinant human insulin (Hefei Tianmai Biotechnology) | INSR | Diabetes mellitus | Hefei Tianmai Biotechnology Development Co., Ltd. | |
| Methoxy polyethylene glycol-epoetin beta | 美信罗 | EpoR | Anemia | Roche Pharma (Schweiz) Ag |
| Recombinant cytokine gene derived protein (Genova Biotech) | 乐复能；Novaferon | IFNAR | Hepatitis B | Beijing Genova Biotech Co.,Ltd. |
| Aflibercept | 艾力雅 | PGF VEGFA | Macular oedema Age-related macular degeneration | Bayer Australia Ltd |
| Alirocumab | 波立达 | PCSK9 | Hypercholesterolemia Atherosclerosis Dyslipidemia | Sanofi-Aventis Groupe |
| Guselkumab | 特诺雅 | IL-23p19 | Psoriasis | Jassen-Cilag International Nv |
| Tislelizumab | 百泽安 | PD-1 | Hodgkin’s disease | BeiGene |
| Agalsidase beta | 法布赞 | Glycosphingolipid | Fabry disease | Genzyme Europe Bv |
| Durvalumab | 英飞凡 | PD-L1 | Non-small cell lung cancer | Astrazeneca Uk Ltd |
| Isophane Protamine Recombinant Human Insulin (Hefei Tianmai Biotechnology) | INSR | Diabetes mellitus | Hefei Tianmai Biotechnology Development Co., Ltd. | |
| Ixekizumab | 拓咨 | IL17A | Psoriasis | Eli Lilly |
| Belimumab | 倍力腾 | BAFF/BLyS | Systemic lupus erythematosus | Glaxosmithkline (Ireland) Ltd |
| Daratumumab | 兆珂 | CD38 | Multiple myeloma | Jassen-Cilag International Nv |
| Certolizumab pegol | 希敏佳 | TNFα | Rheumatoid arthritis | Ucb Pharma Sa |
| Camrelizumab | 艾瑞卡 | PD-1 | Hodgkin’s disease | Suzhou Suncadia Biopharmaceuticals Co., Ltd |
| Elosulfase alfa | 唯铭赞 | CSPGs Keratan sulfate | Type IV mucopolysaccharidosis | Biomarin International Ltd |
| Insulin degludec/Insulin aspart | 诺和佳 | INSR | Diabetes mellitus | Novo Nordisk |
| Denosumab | 安加维 | RANKL | Postmenopausal osteoporosis | Amgen |
| Perfluoropropane-albumin microsphere injection (Nanfang Hospital) | Unidentified | Contrast agent | LZ Pharma | |
| Secukinumab | 可善挺 | IL17A | Plaque psoriasis | Novartis Pharma Schweiz Ag |
| Dulaglutide | 度易达 | GLP1R | Type 2 diabetes mellitus | Eli Lilly Nederland Bv |
| Lanadelumab | 达泽优 | KLKB1 | Precursor B-cell lymphoblastic leukemia-lymphoma | Catalent Inc |
| Botulinum toxin A (Hugel) | SNAP-25 | Nasolabial fold wrinkles | Beijing Four Rings Biopharmaceutical.Co., Ltd. | |
| Idursulfase beta | 海芮思 | GAG | Type II mucopolysaccharidosis | CANbridge Life Sciences Ltd. |
| Agalsidase alfa | 瑞普佳 | α-Gal A | Fabry disease | Vetter Pharma-Fertigung Gmbh & Co Kg |
| Botulinum toxin A (Ipsen) | 吉适 | SNAP-25 | Facial dermatosis | Ipsen Ltd |
| Brodalumab | 立美芙 | IL17RA | Plaque psoriasis | Kyowa Kirin |
| Dupilumab | 达必妥 | IL4RA | Dermatitis atopic | Sanofi-Aventis Group |
| Darbepoetin alfa (Amgen) | 耐斯宝 | EpoR | Anemia | Kyowa Kirin |
| Laronidase | 艾而赞 | DS HS | Type I mucopolysaccharidosis | Genzyme Europe Bv |
| Brentuximab vedotin | 安适利 | CD30 Tubulin | Anaplastic large cell lymphoma Hodgkin's disease | Bsp Pharmaceuticals Spa |
| Recombinant Mycobacterium Tuberculosis Fusion Protein(EC) | 宜卡 | Not available | Diagnostic agent Mycobacterium tuberculosis infection | Anhui Zhifei Longcom Biopharmaceutical Co.,Ltd |
| Vedolizumab | 安吉优 | ITGA4&ITGB7 | Crohn's disease Ulcerative colitis | Takeda Pharma A/S |
| Ustekinumab | 喜达诺 | IL12 IL23 | Plaque psoriasis | Jassen-Cilag International Nv |
| Atezolizumab | 泰圣奇 | PD-L1 | Small cell lung cancer | Roche Registration Gmbh |
| Ado-trastuzumab emtansine | 赫赛莱 | HER2 Tubulin | Breast cancer | Roche Pharma (Schweiz) Ag |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Lenacapavir | Capsid | HIV Infections | Gilead Sciences Ireland Uc | |
| Linzagolix choline | Yselty | GnRH | Uterine Neoplasms | Obseva Ireland Ltd |
| Vutrisiran | AMVUTTRA | TTR | Transthyretin amyloidosis | Alnylam Japan Kk |
| Tirzepatide | Mounjaro | GLP1R GIPR | Diabetes Mellitus, Type 2 | Eli Lilly Japan Kk |
| Mitapivat | Pyrukynd | Pyruvate kinase | Pyruvate kinase deficiency | Agios Netherlands Bv |
| Daridorexant | Quviviq | OX1R OX2R | Sleep Initiation and Maintenance Disorders | Idorsia Ltd |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Satralizumab | Enspryng | IL6RAIL6RB | Neuromyelitis optica | Roche Registration Gmbh |
| Azathioprine | Jayempi | HGPRT | Kidney transplant rejection | Nova Laboratories Ireland Ltd |
| Tralokinumab | Adtralza | IL13 | Dermatitis atopic | LEO Pharma A/S |
| Evinacumab | Evkeeza | ANGPTL3 | Hypercholesterolemia | Regeneron Ireland Designated Activity Company |
| Duvelisib | Copiktra | PI3KγPI3Kδ | Follicular center cell lymphoma Chronic lymphocytic leukemia | Verastem Europe Gmbh |
| Ponesimod | Ponvory | EDG1 | Relapsing-remitting multiple sclerosis | Jassen-Cilag International Nv |
| Drospirenone/Estetrol | Lydisilka | ARERsMRPR | Contraception | Estetra SPRL |
| Berotralstat | Orladeyo | KLKB1 | Hereditary angioedema | BioCryst Ireland Ltd |
| Dostarlimab | Jemperli | PD-1 | Endometrial cancer | Glaxosmithkline (Ireland) Ltd |
| Somapacitan | Sogroya | GHR | Growth hormone deficiency | Novo Nordisk A/S |
| Cenobamate | Ontozry | GABAARSCNA | Epilepsy | Arvelle Therapeutics Netherlands B. V. |
| Remimazolam Besilate | Byfavo | GABAAR | Sedation | Paion Pharma |
| Icosapent ethyl | Vazkepa | Unidentified | Dyslipidemia | Amarin Pharmaceuticals Ireland Ltd |
| Selinexor | Nexpovio | XPO1 | Multiple myeloma | Karyopharm Europe Gmbh |
| Risdiplam | Evrysdi | SMN | Spinal muscular atrophy | Roche Registration Gmbh |
| Tucatinib | Tukysa | HER2 | Metastatic carcinoma Breast cancer | Seagen Netherlands Bv |
| Moxetumomab pasudotox | Lumoxiti | CD22 | Hairy cell leukemia | Astrazeneca Ab |
| Fedratinib | Inrebic | FLT3JAK2 | Myelofibrosis Disorder myeloproliferative | Celgene Europe Bv |
| Fostemsavir Tromethamine | Rukobia | HIV envelope protein gp120 | HIV infection | Viiv Healthcare Bv |
| Fam-trastuzumab deruxtecan | Enhertu | HER2TOP1 | Breast cancer | Daiichi Sankyo Europe Gmbh |
| Tagraxofusp-erzs | Elzonris | IL3RA | Blastic plasmacytoid dendritic cell neoplasiaLymphoma | Stemline Therapeutics Inc |
| Baloxavir Marboxil | Xofluza | PA | Influenza viral infections | Roche Registration Gmbh |
| Satralizumab | Enspryng | IL6RA IL6RB | Neuromyelitis optica | Roche Registration Gmbh |
| Azathioprine | Jayempi | HGPRT | Kidney transplant rejection | Nova Laboratories Ireland Ltd |
| Tralokinumab | Adtralza | IL13 | Dermatitis atopic | LEO Pharma A/S |
| Evinacumab | Evkeeza | ANGPTL3 | Hypercholesterolemia | Regeneron Ireland Designated Activity Company |
| Duvelisib | Copiktra | PI3Kγ PI3Kδ | Follicular center cell lymphoma Chronic lymphocytic leukemia | Verastem Europe Gmbh |
| Ponesimod | Ponvory | EDG1 | Relapsing-remitting multiple sclerosis | Jassen-Cilag International Nv |
| Drospirenone/Estetrol | Lydisilka | AR ERs MR PR | Contraception | Estetra SPRL |
| Berotralstat | Orladeyo | KLKB1 | Hereditary angioedema | BioCryst Ireland Ltd |
| Dostarlimab | Jemperli | PD-1 | Endometrial cancer | Glaxosmithkline (Ireland) Ltd |
| Somapacitan | Sogroya | GHR | Growth hormone deficiency | Novo Nordisk A/S |
| Cenobamate | Ontozry | GABAAR SCNA | Epilepsy | Arvelle Therapeutics Netherlands B. V. |
| Remimazolam Besilate | Byfavo | GABAAR | Sedation | Paion Pharma |
| Icosapent ethyl | Vazkepa | Unidentified | Dyslipidemia | Amarin Pharmaceuticals Ireland Ltd |
| Selinexor | Nexpovio | XPO1 | Multiple myeloma | Karyopharm Europe Gmbh |
| Risdiplam | Evrysdi | SMN | Spinal muscular atrophy | Roche Registration Gmbh |
| Tucatinib | Tukysa | HER2 | Metastatic carcinoma Breast cancer | Seagen Netherlands Bv |
| Moxetumomab pasudotox | Lumoxiti | CD22 | Hairy cell leukemia | Astrazeneca Ab |
| Fedratinib | Inrebic | FLT3 JAK2 | Myelofibrosis Disorder myeloproliferative | Celgene Europe Bv |
| Fostemsavir Tromethamine | Rukobia | HIV envelope protein gp120 | HIV infection | Viiv Healthcare Bv |
| Fam-trastuzumab deruxtecan | Enhertu | HER2 TOP1 | Breast cancer | Daiichi Sankyo Europe Gmbh |
| Tagraxofusp-erzs | Elzonris | IL3RA | Blastic plasmacytoid dendritic cell neoplasia Lymphoma | Stemline Therapeutics Inc |
| Baloxavir Marboxil | Xofluza | PA | Influenza viral infections | Roche Registration Gmbh |
| Nirmatrelvir/Ritonavir | Paxlovid | 3CLp HIV-1 protease | Coronavirus Disease 2019 | Pfizer Inc. |
| Maribavir | Livtencity | UL97 | Cytomegalovirus Infections | Takeda Pharmaceutical Co Ltd |
| Asciminib | Scemblix | Bcr-Abl | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Novartis Europharm Ltd |
| Maralixibat | LIVMARLI | IBAT | Alagille Syndrome | Mirum Pharmaceuticals |
| Avacopan | Tavneos | C5AR | Granulomatosis with Polyangiitis | Vifor Fresenius Medical Care Renal Pharma France Vifor Sa |
| Abrocitinib | Cibinqo | JAK1 | Dermatitis, Atopic | Pfizer Inc. |
| Difelikefalin | KORSUVA | KOR1 | Pruritus | Vifor Fresenius Medical Care Renal Pharma France |
| Odevixibat | Bylvay | IBAT | Progressive familial intrahepatic cholestasis | Albireo Ab |
| Finerenone | Kerendia | MR | Renal Insufficiency, Chronic | Bayer Healthcare Company Ltd. |
| Sotorasib | LUMAKRAS | KRAS G12C | Carcinoma, Non-Small-Cell Lung | Amgen |
| Relugolix/Estradiol/Norethindrone Acetate | MYFEMBREE | ERs SIRPA PR GnRHR | Pain | Myovant Sciences |
| Leuprolide mesylate | CAMCEVI | GnRH | Prostatic Neoplasms | Accord Healthcare Slu |
| Pegcetacoplan | Empaveli | C3 | Hemoglobinuria, Paroxysmal | Swedish Orphan Biovitrum Ab (Publ) |
| Potassium citrate/Potassium bicarbonate | Undisclosed | Acidosis, Renal Tubular | Advicenne Pharma | |
| Fosdenopterin | Molybdenum cofactor | Molybdenum cofactor deficiency | Bridgebio Pharma Inc | |
| Melphalan Flufenamide | Pepaxti | DNA Aminopeptidase | Multiple Myeloma | Oncopeptides Ab |
| Voclosporin | Lupkynis | Calcineurin | Lupus Nephritis | Aurinia Pharmaceuticals Inc |
| Vericiguat | Verquvo | sGC | Heart Failure | Bayer Healthcare Company Ltd. |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Trastuzumab/Pertuzumab | Phesgo | HER2 | Breast cancer | Roche Registration Gmbh |
| Autologous CD34+ cells encoding ARSA gene | Libmeldy | ARSA | Metachromatic cerebral white matter lesion | Orchard Therapeutics (Netherlands) Bv |
| Peanut (Arachis hypogaea) Allergen Powder-dnfp | Palforzia | Not available | Peanut allergy | Aimmune Therapeutics Ireland Ltd |
| Cabotegravir | Vocabria | HIV integrase | HIV infection | Viiv Healthcare Bv |
| Inclisiran sodium | Leqvio | PCSK9Small interfering RNA | Dyslipidemia Hypercholesterolemia | Novartis Europharm Ltd |
| Lumasiran sodium | Oxlumo | HAO1Small interfering RNA | Primary hyperoxaluria | Alnylam Netherlands Bv |
| Obiltoxaximab | Obiltoxaximab SFL | Antrax lethal toxin | Bacillus anthracis infection | SFL Pharmaceuticals Deutschland GmbH |
| Acalabrutinib | Calquence | BTK | Chronic lymphocytic leukemia | Astrazeneca Ab |
| Crizanlizumab-tmca | Adakveo | SELP | Sickle cell anemia | Novartis Europharm Ltd |
| Amikacin Sulfate | Arikayce liposomal | 30S subunit | Respiratory Tract Infections | Insmed Netherlands Bv |
| Filgotinib Maleate | Jyseleca | JAK1 | Rheumatoid arthritis | Gilead Sciences Ireland Uc |
| Avapritinib | Ayvakyt | KITPDGFR-α | Gastrointestinal stromal tumor | Blueprint Medicines (Netherlands) Bv |
| Imlifidase | Idefirix | IgG | Kidney transplant rejection | Hansa Biopharma Ab |
| Belantamab mafodotin | Blenrep | BCMATubulin | Multiple myeloma | Glaxosmithkline (Ireland) Ltd |
| Elexacaftor/ivacaftor/tezacaftor | Kaftrio | CFTRPGY1 | Cystic fibrosis | Vertex Pharmaceuticals (Ireland) Ltd |
| Bulevirtide Acetate | Hepcludex | HBV polNTCP | Chronic hepatitis D | Myr Gmbh |
| Pretomanid | Dovprela (previously Pretomanid FGK) | DNA | Multidrug-resistant pulmonary tuberculosis | Fgk Representative Service Gmbh |
| Entrectinib | Rozlytrek | ALKNTRK2NTRK3ROSTRKA | Non-small cell lung cancerSolid tumor | Roche Registration Gmbh |
| Alpelisib | Piqray | PI3Kα | Breast cancer | Novartis Europharm Ltd |
| Lefamulin | Xenleta | 50S ribosomal subunit | Pneumonia bacterial Community acquired infection | Nabriva Therapeutics Ireland Designated Activity Company |
| Remdesivir | Veklury | RNA-directed RNA polymeraseViral proteins | Novel coronavirus pneumonia Coronavirus infection | Gilead Sciences Ireland Uc |
| Glasdegib | Daurismo | SMO | Acute myelocytic leukaemia | Pfizer Europe Ma Eeig |
| Luspatercept | Reblozyl | TGF-β | Anemia Myelodysplastic syndrome Β-Mediterranean anemia | Celgene Europe Bv |
| Isatuximab | Sarclisa | CD38 | Multiple myeloma | Sanofi-Aventis |
| Ozanimod hydrochloride | Zeposia | S1PRs | Relapsing-remitting multiple sclerosis | Bristol-Myers Squibb Pharma Eeig |
| Onasemnogene abeparvovec | Zolgensma | SMN | Spinal muscular atrophy | Novartis Gene Therapies EU Ltd |
| Cefiderocol Sulfate Tosylate | Fetcroja | PBPs | Gram-negative bacterial infection | Shionogi Bv |
| Treprostinil | Trepulmix | PTGIR | Pulmonary hypertension | Scipharm Sàrl |
| Semaglutide oral (Novo Nordisk) | Rybelsus | GLP1R | Type 2 diabetes mellitus | Novo Nordisk A/S |
| Bempedoic Acid | Nilemdo | ACLY | Hypercholesterolemia Dyslipidemia | Daiichi Sankyo Europe Gmbh |
| Crisaborole | Staquis | PDE4 | Dermatitis atopic | Pfizer Europe Ma Eeig |
| Darolutamide | Nubeqa | AR | Castration-resistant prostate cancer | Bayer AG |
| Bempedoic Acid/Ezetimibe | Nustendi | ACLYNPC1L1 | Dyslipidemia Hypercholesterolemia | Daiichi Sankyo Europe Gmbh |
| Givosiran | Givlaari | ALAS1Small interfering RNA | Porphyria hepatic | Alnylam Netherlands Bv |
| Brolucizumab | Beovu | VEGFA | Wet macular degeneration | Novartis Europharm Ltd |
| Solriamfetol | Sunosi | DATNET | Narcolepsy Obstructive sleep apnoea syndrome | Jazz Pharmaceuticals Ireland Ltd |
| Polatuzumab vedotin | Polivy | CD79BTubulin | B-cell lymphoma | Roche Registration Gmbh |
| Siponimod | Mayzent | EDG1S1PR5 | Relapsing-remitting multiple sclerosis | Novartis Europharm Ltd |
| Fostamatinib disodium hexahydrate | Tavlesse | Syk | Platelets decreased | Rigel Pharmaceuticals Bv |
| Osilodrostat phosphate | Isturisa | CYP11B1 | Cushing's syndrome | Novartis Europharm Ltd |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Glucagon | Baqsimi | GCGR | Diabetes mellitus | Eli Lilly Nederland Bv |
| Upadacitinib | Rinvoq | JAK1 | Rheumatoid arthritis | Abbvie Deutschland Gmbh & Co Kg |
| Delafloxacin | Quofenix | Bacterial DNA gyraseTopoisomerase IV | Bacterial dermatosis | A. Menarini Industrie Farmaceutiche Riunite Srl |
| Romosozumab | Evenity | SO | Postmenopausal osteoporosis | Ucb Pharma Sa |
| Netarsudil Dimesylate | Rhokiinsa | CTGFNETRHOKTGFBR2 | Ocular hypertension Open angle glaucoma | Aerie Pharmaceuticals Ireland Ltd |
| Gilteritinib Fumarate | Xospata | AXLFLT3 | Acute myelocytic leukaemia | Astellas Pharma Europe Bv |
| Botulinum toxin A (Daewoong Pharmaceuticals) | Nuceiva | SNAP-25 | Nasolabial fold wrinkles | Evolus Pharma Ltd |
| Ibalizumab-uiyk | Trogarzo | CD4Viral fusion proteins | HIV infection | Theratechnologies Europe Ltd |
| Levodopa | Inbrija | DRDs | Parkinson’s disease | Acorda Therapeutics Ireland Ltd |
| Cannabidiol | Epidyolex | CB1 | Lennox-Gastaut syndrome Dravet syndrome | Gw Pharma (International) Bv |
| Larotrectinib sulfate | Vitrakvi | NTRKNTRK2NTRK3TRKA | Neoplasm | Bayer AG |
| Angiotensin II | Giapreza | AT2 | Hypotension Shock | Paion Deutschland Gmbh |
| Ravulizumab | Ultomiris | C5 | Paroxysmal nocturnal hemoglobinuria | Alexion Europe Sas |
| Cemiplimab | Libtayo | PD-1 | Squamous cell carcinoma | Regeneron Ireland Uc |
| Turoctocog alfa pegol | Esperoct | F10 | Hemophilia A | Novo Nordisk A/S |
| Talazoparib | Talzenna | PARP-2PARP1 | Breast cancer | Pfizer Europe Ma Eeig |
| Avatrombopag Maleate | Doptelet | TpoR | Platelets decreased | Swedish Orphan Biovitrum Ab (Publ) |
| Autologous CD34+ cells encoding βA-T87Q-globin gene | Zynteglo | HBB | β-Mediterranean anemia | Bluebird Bio (Netherlands) Bv |
| Lorlatinib | Lorviqua | ALKROS | Non-small cell lung cancer | Pfizer Europe Ma Eeig |
| Pegvaliase-pqpz | Palynziq | PAH | Hyperphenylalaninaemia | Biomarin International Ltd |
| Volanesorsen | Waylivra | APOC3 | Type I hyperlipoproteinemia | Akcea Therapeutics Ireland Ltd |
| Andexanet alfa | Ondexxya | PT | Drug-related side effects and adverse reactions | Alexion Europe Sas |
| Zanamivir | Dectova | NA | Influenza viral infections | Glaxosmithkline Trading Services Ltd |
| Risankizumab | Skyrizi | IL23 | Psoriasis | Abbvie Deutschland Gmbh & Co Kg |
| Sotagliflozin | Zynquista | SGLT1SGLT2 | Type 1 diabetes mellitus | Navigant Germany Gmbh |
| Dacomitinib | Vizimpro | EGFRHER2HER4 | Non-small cell lung cancer | Pfizer Europe Ma Eeig |
| Fremanezumab | Ajovy | CGRP | Migraine | Teva Gmbh |
| Emtricitabine/Tenofovir disoproxil phosphate | Emtricitabin/Tenofovirdisoproxil Hormosan 200 mg/245 mg Filmtabletten | HIV-1 RTRT | HIV infection | Hormosan Pharma Gmbh |
| Amlodipine Besylate/Irbesartan/Hydrochlorothiazide | Amlodipin/Irbersartan/Hydrochlorothiazide WIN MEDICA 5 mg/150 mg/12,5 mg, film-coated tablet | AT1Thiazide-sensitive sodium-chloride cotransporterVDCCs | Hypertension | Win Medica Sa |
| Tobramycin | Vantobra (previously Tobramycin PARI) | 30S subunit | Cystic fibrosisRespiratory tract infection | Pari Pharma Gmbh |
| Naldemedine Tosylate | Rizmoic | MOR1 | Constipation | Shionogi Bv |
| Lusutrombopag | Mulpleo (previously Lusutrombopag Shionogi) | TpoR | Platelets decreased | Shionogi Bv |
| Ropeginterferon alfa-2b | Besremi | IFNAR | Polycythemia vera | Aop Orphan Pharmaceuticals Ag |
| Apalutamide | Erleada | AR | Prostatic cancer |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Mexiletine Hydrochloride | Namuscla | SCNA | Myotonic disorders | Lupin Europe Gmbh |
| Sitagliptin Hydrochloride | Sitagliptin Alter 50 mg film-coated tablets | DPP4 | Type 2 diabetes mellitus | Laboratorios Alter Sa |
| Damoctocog alfa pegol | Jivi | F10 | Hemophilia A | Bayer AG |
| Voretigene neparvovec-rzyl | Luxturna | RPE65 | Retinal malnutrition atrophyVisual disturbances | Novartis Europharm Ltd |
| Brigatinib | Alunbrig | ALKEGFRFLT3IGF1RROS | Non-small cell lung cancer | Takeda Pharma A/S |
| Mogamulizumab | Poteligeo | CCR4 | Sezary syndrome Mycosis fungoides | Kyowa Kirin Holdings Bv |
| Lanadelumab | Takhzyro | KLKB1 | Hereditary angioedema | Shire Pharmaceuticals Ireland Ltd |
| Doravirine | Pifeltro | RT | HIV infection | Merck Sharp & Dohme Bv |
| Buprenorphine Hydrochloride | Buvidal | KOR1MOR1 | Dependence on opiates | Camurus Ab |
| Galcanezumab | Emgality | CGRP | Migraine | Eli Lilly Nederland Bv |
| Abemaciclib | Verzenios | CDK4CDK6 | Breast cancer | Eli Lilly Nederland Bv |
| Durvalumab | Imfinzi | PD-L1 | Non-small cell lung cancer | Astrazeneca Ab |
| Eravacycline Dihydrochloride | Xerava | 30S subunit | Abdominal infection Bacterial infection | Tetraphase Pharmaceuticals Ireland Ltd |
| Binimetinib | Mektovi | MEK1MEK2 | Melanoma | Pierre Fabre Médicament Production |
| Vigabatrin | Kigabeq | GABAAR | Partial seizures Infantile spasms | Orphelia Pharma |
| Encorafenib | Braftovi | B-raf | Melanoma | Pierre Fabre Médicament Production |
| Tildrakizumab-asmn | Ilumetri | IL23IL23R | Psoriasis | Almirall Sa |
| Neratinib Maleate | Nerlynx | EGFRHER2HER4 | Breast cancer | Pierre Fabre Médicament Production |
| Von Willebrand factor (Recombinant) | Veyvondi | F8 | Von Willebrand’s disease | Baxalta Innovations Gmbh |
| Caplacizumab | Cablivi | vWF | Thrombotic thrombocytopenic purpura | Ablynx Nv |
| Vestronidase alfa-vjbk | Mepsevii | GAG | Tape VII mucopolysaccharidosis | Ultragenyx Germany Gmbh |
| Tisagenlecleucel | Kymriah | CD19 | Diffuse large B-cell lymphoma Precursor B-cell lymphoblastic leukemia-lymphoma | Novartis Europharm Ltd |
| Metreleptin | Myalepta | LEPR | Familial localized lipodystrophy | Amryt Pharmaceuticals Dac |
| Erenumab-aooe | Aimovig | CALCRLCGRP | Migraine | Novartis Europharm Ltd |
| Brexpiprazole | Rxulti | 5-HT1A5-HT2ADRD2 | Schizophrenia | Otsuka Pharmaceutical Netherlands Bv |
| Inotersen sodium | Tegsedi | Small interfering RNATTR | Amyloidosis | Akcea Therapeutics Ireland Ltd |
| Glibenclamide | Amglidia | SUR1 | Diabetes mellitus | Ammtek |
| Rucaparib Camsylate | Rubraca | PARP-2PARP-3PARP1 | Ovarian cancer | Clovis Oncology Uk Ltd |
| Gemtuzumab ozogamicin | Mylotarg | CD33DNA | Acute myelocytic leukaemia | Pfizer Europe Ma Eeig |
| Peramivir Hydrate | Alpivab | NA | Influenza viral infections | Biocryst Pharmaceuticals Inc |
| Velmanase alfa | Lamzede | Mannose | α-mannosidosis | Chiesi Farmaceutici S.p.A. |
| Sodium zirconium cyclosilicate | Lokelma | Potassium | Hyperkalemia | Astrazeneca Ab |
| Ertugliflozin | Steglatro | SGLT2 | Type 2 diabetes mellitus | Merck Sharp & Dohme Bv |
| Emicizumab | Hemlibra | F10F9 | Hemophilia A | Roche Registration Limited |
| Burosumab | Crysvita | FGF23 | Hyperphosphaturia | Kyowa Kirin Holdings Bv |
| Semaglutide | Ozempic | GLP1R | Type 2 diabetes mellitus | Novo Nordisk A/S |
| Ocrelizumab | Ocrevus | CD20 | Multiple sclerosis | Roche Registration Gmbh |
| Benralizumab | Fasenra | IL5RA | Asthma | Astrazeneca Ab |
| Budesonide | Jorveza | GR | Esophageal disorder | Dr. Falk Pharma Gmbh |
| Letermovir | Prevymis | UL30UL54 | Cytomegalovirus infection | Merck Sharp & Dohme Bv |
| Rurioctocog alfa pegol | Adynovi | F10 | Hemophilia A | Baxalta Innovations Gmbh |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Noxiptiline hydrochloride | Nortriptyline 10mg Tablet | Unidentified | Depressive disorder | Ria Generics Ltd |
| Niraparib Tosylate | Zejula | PARP-2PARP1 | Ovarian cancer Peritoneal carcinoma Fallopian tube cancer | Glaxosmithkline (Ireland) Ltd |
| Padeliporfin di-potassium | Tookad | Unidentified | Prostatic cancer | Steba Biotech Sa |
| Guselkumab | Tremfya | IL-23p19 | Psoriasis | Janssen-Cilag International NV |
| Naloxone Hydrochloride | Nyxoid | Opioid receptorsmu/kappa/delta | Dependence on opiates | Mundipharma Corporation (Ireland) Ltd |
| Dupilumab | Dupixent | IL4RA | Dermatitis atopic | Sanofi-Aventis |
| Lutetium (177Lu) oxodotreotide | Lutathera | SSTR2 | Neuroendocrine tumor | Advanced Accelerator Applications |
| Atezolizumab | Tecentriq | PD-L1 | Non-small cell lung cancer Transitional cell carcinoma | Roche Registration Gmbh |
| Midostaurin | Rydapt | FLT3KITPDGFR-βPKC-αVEGFR2 | Mastocytosis Acute myelocytic leukaemia | Novartis Europharm Ltd |
| Avelumab | Bavencio | PD-L1 | Merkel cell carcinoma | Merck Europe Bv |
| Telotristat Etiprate | Xermelo | TPH1TPH2 | Neuroendocrine tumor Carcinoid tumor | Ipsen Pharma |
| Trientine Hydrochloride | Cuprior | Unidentified | Wilson-Brocq's disease | Gmp-Orphan Sa |
| Tivozanib | Fotivda | VEGFR1VEGFR2VEGFR3 | Renal cell carcinoma | Eusa Pharma (Netherlands) Bv |
| Ribociclib Succinate | Kisqali | CDK4CDK6 | Breast cancer | Novartis Europharm Ltd |
| Patiromer Sorbitex Calcium | Veltassa | Potassium | Hyperkalemia | Vifor Fresenius Medical Care Renal Pharma Ltd |
| Brodalumab | Kyntheum | IL17RA | Psoriasis | LEO Pharma A/S |
| Cariprazine Hydrochloride | Reagila | 5-HT1A5-HT2ADRD2 | Schizophrenia | Gedeon Richter |
| Cenegermin | Oxervate | NGFR | Keratitis | Dompé Pharmaceutici Spa |
| Desfesoterodine Succinate | Tovedeso 3,5 mg Retardtabletten | Adrenoceptors | Overactive bladder | Ratiopharm Gmbh |
| Inotuzumab Ozogamicin | Besponsa | CD22DNA | Acute lymphocytic leukemia | Pfizer Europe Ma Eeig |
| Sarilumab | Kevzara | IL6RAIL6RB | Rheumatoid arthritis | Sanofi-Aventis |
| Nonacog beta pegol | Refixia | F10 | Hemophilia B | Novo Nordisk A/S |
| Pentosan Polysulfate Sodium | Elmiron | FGF1FGF2 | Interstitial Cystitis | Bene-Arzneimittel Gmbh |
| Cerliponase alfa | Brineura | IGF2R | Neuronal ceroidlipofuscinosis | Biomarin International Ltd |
| Nusinersen sodium | Spinraza | SMNSmall interfering RNA | Spinal muscular atrophy | Biogen Netherlands Bv |
| Fluciclovine F 18 | Axumin | Unidentified | Prostatic cancer | Blue Earth Diagnostics Ireland Ltd |
| Dinutuximab beta | Qarziba (previously Dinutuximab beta EUSA and Dinutuximab beta Apeiron) | GD2 | Neuroblastoma | Eusa Pharma (Netherlands) Bv |
| Daratumumab | Darzalex | CD38 | Multiple myeloma | Janssen-Cilag International N.V. |
| Rolapitant Hydrochloride Hydrate | Varuby | NK1R | Nausea Vomiting | Tesaro Bio Netherlands Bv |
| Chenodeoxycholic acid | Chenodeoxycholic acid Leadiant (previously known as Chenodeoxycholic acid sigma-tau) | Unidentified | Cerebrotendinous xanthomatosisInherited metabolic deficiency | Leadiant Gmbh |
| Melphalan | DNA | Multiple myeloma | Tillomed Pharma Gmbh | |
| Methotrexate | Jylamvo | DHFR | Psoriatic arthritis Acute lymphocytic leukemia Rheumatoid arthritis | Therakind (Europe) Ltd |
| Tofacitinib Citrate | Xeljanz | JAK | Rheumatoid arthritis | Pfizer Europe Ma Eeig |
| Mechlorethamine Hydrochloride | Ledaga | DNA | Dermatitis fungoides | Helsinn Birex Pharmaceuticals Ltd |
| Alectinib Hydrochloride | Alecensa | ALKRET | Non-small cell lung cancer | Roche Registration Gmbh |
| Baricitinib | Olumiant | JAK1JAK2 | Rheumatoid arthritis | Eli Lilly Nederland Bv |
| Bezlotoxumab | Zinplava | BTXtoxB | Clostridium difficile infection | Merck Sharp & Dohme Bv |
| Cysteamine hydrochloride | Cystadrops | GSH-S | Cystinosis | Recordati Rare Diseases Inc |
| Insulin glargine/Lixisenatide | Suliqua | GLP1RINSR | Type 2 diabetes mellitus | Sanofi-Aventis |
| Tenofovir Alafenamide Fumarate | Vemlidy | RT | Chronic hepatitis B | Gilead Sciences Ireland Uc |
| Lonoctocog alfa | Afstyla | F10 | Hemophilia A | Csl Behring Gmbh |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Adagrasib | KRAZATI | KRAS G12C | Carcinoma, Non-Small-Cell Lung | Mirati Therapeutics Inc |
| Olutasidenib | IDH1 | Leukemia, Myeloid, Acute | Rigel Pharmaceuticals Inc | |
| Futibatinib | LYTGOBI | FGFR4 FGFR1 FGFR3 FGFR2 | Cholangiocarcinoma | Taiho Oncology Inc |
| Gadopiclenol | Elucirem | Unidentified | Contrast agents | Guerbet/Liebel-Flarsheim |
| Deucravacitinib | Sotyktu | TYK2 | Psoriasis | Bristol-Myers Squibb Kk |
| Bupropion Hydrochloride/Dextromethorphan Hydrobromide | Auvelity | NMDAR DAT Adrenoceptors | Depressive Disorder | Axsome Therapeutics Inc |
| Venlafaxine Besylate | NET SERT | Anxiety Disorders | Almatica Pharma LLC | |
| Vutrisiran | AMVUTTRA | TTR | Transthyretin amyloidosis | Alnylam Japan Kk |
| Sodium Phenylbutyrate/Tauroursodeoxycholic acid | Albrioza | HDAC GPBAR1 | Amyotrophic Lateral Sclerosis | Amylyx Pharmaceuticals Inc |
| Testosterone Cypionate | Depo-testosterone | AR | Hypogonadism | |
| Tirzepatide | Mounjaro | GLP1R GIPR | Diabetes Mellitus, Type 2 | Eli Lilly Japan Kk |
| Amoxicillin/Vonoprazan Fumarate | VOQUEZNA DUAL PAK | PBPs H+/K+ ATPase | Helicobacter pylori infection | Phathom Pharmaceuticals Inc |
| Mavacamten | Camzyos | Cardiac myosin | Cardiomyopathy, Hypertrophic | Bristol-MyersSquibb |
| Oteseconazole | Vivjoa | CYP51 | Candidiasis, Vulvovaginal | Mycovia Pharmaceuticals Inc |
| Lutetium | PLUVICTO | PSMA | Prostatic Neoplasms, Castration-Resistant | Advanced Accelerator Applications Usa Inc |
| Ganaxolone | ZTALMY | GABAAR | Seizures | Marinus Pharmaceuticals Inc |
| Pacritinib | VONJO | JAK2 CSF1R FLT3 IRAK1 CDK2 | Primary Myelofibrosis | Cti Biopharma Corp |
| Mitapivat | Pyrukynd | Pyruvate kinase | Pyruvate kinase deficiency | Agios Netherlands Bv |
| Daridorexant | Quviviq | OX1R OX2R | Sleep Initiation and Maintenance Disorders | Idorsia Ltd |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Dabigatran etexilate | Pradaxa | PT | Pellets | Boehringer Ingelheim Pharmaceuticals Inc |
| Ephedrine Hydrochloride | Rezipres | Adrenoceptors | Injectable | Eton Pharmaceuticals Inc |
| Aducanumab | Aduhelm | APP | Injectable | Biogen Inc |
| Infigratinib | Truseltiq | FGFR1FGFR2FGFR3 | Capsule | Qed Therapeutics Inc |
| Sotorasib | Lumakras | KRAS | Tablet | Amgen Inc |
| Piflufolastat F 18 | Pylarify | GCPII | Injectable | Progenics Pharmaceuticals Inc |
| Relugolix/Estradiol/Norethindrone Acetate | Myfembree | ERsGnRHRPRSIRPA | Tablet | Myovant Sciences |
| Amivantamab | Rybrevant | EGFRc-Met/HGFR | Injectable | Janssen Biotech Inc |
| Pegcetacoplan | Empaveli | C3 | InjectableSolution | Apellis Pharmaceuticals Inc |
| Loncastuximab tesirine | Zynlonta | CD19DNA | Injectable | Adc Therapeutics Sa |
| Dostarlimab | Jemperli | PD-1 | Injectable | Glaxosmithkline |
| Drospirenone/Estetrol | Nextstellis | ARERsMRPR | TabletTablet, Chewable, Tablet, Capsule | Mayne Pharma |
| Viloxazine Hydrochloride | Qelbree | CYPIA2NET | Capsule, Extended Release | Supernus Pharmaceuticals Inc |
| Idecabtagene vicleucel | Abecma | BCMA | Solution | Celgene Corp |
| Dasiglucagon | Zegalogue | GCGR | Injectable | Zealand PharmaZealand Pharma A/S |
| Ponesimod | Ponvory | EDG1 | Tablet | Janssen Pharmaceuticals Inc |
| Tivozanib | Fotivda | VEGFR1VEGFR2VEGFR3 | Capsule | Aveo Pharmaceuticals Inc |
| Serdexmethylphenidate/Dexmethylphenidate | Azstarys | DATNETα-adrenoceptors | Capsule | Commcave Therapeutics SA |
| Fosdenopterin | Nulibry | Molybdenum cofactor | Injectable | Origin BiosciencesOrigin Biosciences Inc |
| Melphalan Flufenamide | Pepaxto | AminopeptidaseDNA | Injectable | Oncopeptides Ab |
| Casimersen | Amondys 45 | Dystroglycan | Solution | Sarepta Therapeutics Inc |
| Bamlanivimab | Unidentified | Eli Lilly and Co | ||
| Trilaciclib Dihydrochloride | Cosela | CDK4CDK6 | InjectablePowder | G1 Therapeutics Inc |
| Evinacumab | Evkeeza | ANGPTL3 | Solution | Regeneron Pharmaceuticals |
| Lisocabtagene maraleucel (Celgene/Juno Therapeutics) | Breyanzi | CD19 | Injectable, Suspension | Bristol-Myers Squibb |
| Umbralisib | Ukoniq | PI3Kδ | Tablet | Tg Therapeutics Inc |
| Tepotinib hydrochloride hydrate | Tepmetko | c-Met/HGFR | Tablet | Emd Serono Inc |
| Voclosporin | Lupkynis | Calcineurin | Capsule | Aurinia Pharmaceuticals Inc |
| Cabotegravir/Rilpivirine | CabenuvaVocabria | HIV integraseRT | Suspension, Extended ReleaseTablet, Film Coated | Viiv Healthcare |
| Cabotegravir | Vocabria | HIV integrase | Tablet, Film Coated | Viiv Healthcare |
| Vericiguat | Verquvo | sGC | Tablet | Merck Sharp Dohme |
| Dabigatran etexilate | Pradaxa | PT | Pellets | Boehringer Ingelheim Pharmaceuticals Inc |
| Ephedrine Hydrochloride | Rezipres | Adrenoceptors | Injectable | Eton Pharmaceuticals Inc |
| Aducanumab | Aduhelm | APP | Injectable | Biogen Inc |
| Infigratinib | Truseltiq | FGFR1 FGFR2 FGFR3 | Capsule | Qed Therapeutics Inc |
| Sotorasib | Lumakras | KRAS | Tablet | Amgen Inc |
| Piflufolastat F 18 | Pylarify | GCPII | Injectable | Progenics Pharmaceuticals Inc |
| Relugolix/Estradiol/Norethindrone Acetate | Myfembree | ERs GnRHR PR SIRPA | Tablet | Myovant Sciences |
| Amivantamab | Rybrevant | EGFR c-Met/HGFR | Injectable | Janssen Biotech Inc |
| Pegcetacoplan | Empaveli | C3 | Injectable Solution | Apellis Pharmaceuticals Inc |
| Loncastuximab tesirine | Zynlonta | CD19 DNA | Injectable | Adc Therapeutics Sa |
| Dostarlimab | Jemperli | PD-1 | Injectable | Glaxosmithkline |
| Drospirenone/Estetrol | Nextstellis | AR ERs MR PR | Tablet Tablet, Chewable, Tablet, Capsule | Mayne Pharma |
| Viloxazine Hydrochloride | Qelbree | CYPIA2 NET | Capsule, Extended Release | Supernus Pharmaceuticals Inc |
| Idecabtagene vicleucel | Abecma | BCMA | Solution | Celgene Corp |
| Dasiglucagon | Zegalogue | GCGR | Injectable | Zealand Pharma Zealand Pharma A/S |
| Ponesimod | Ponvory | EDG1 | Tablet | Janssen Pharmaceuticals Inc |
| Tivozanib | Fotivda | VEGFR1 VEGFR2 VEGFR3 | Capsule | Aveo Pharmaceuticals Inc |
| Serdexmethylphenidate/Dexmethylphenidate | Azstarys | DAT NET α-adrenoceptors | Capsule | Commcave Therapeutics SA |
| Fosdenopterin | Nulibry | Molybdenum cofactor | Injectable | Origin Biosciences Origin Biosciences Inc |
| Melphalan Flufenamide | Pepaxto | Aminopeptidase DNA | Injectable | Oncopeptides Ab |
| Casimersen | Amondys 45 | Dystroglycan | Solution | Sarepta Therapeutics Inc |
| Bamlanivimab | Unidentified | Eli Lilly and Co | ||
| Trilaciclib Dihydrochloride | Cosela | CDK4 CDK6 | Injectable Powder | G1 Therapeutics Inc |
| Evinacumab | Evkeeza | ANGPTL3 | Solution | Regeneron Pharmaceuticals |
| Lisocabtagene maraleucel (Celgene/Juno Therapeutics) | Breyanzi | CD19 | Injectable, Suspension | Bristol-Myers Squibb |
| Umbralisib | Ukoniq | PI3Kδ | Tablet | Tg Therapeutics Inc |
| Tepotinib hydrochloride hydrate | Tepmetko | c-Met/HGFR | Tablet | Emd Serono Inc |
| Voclosporin | Lupkynis | Calcineurin | Capsule | Aurinia Pharmaceuticals Inc |
| Cabotegravir/Rilpivirine | Cabenuva Vocabria | HIV integrase RT | Suspension, Extended Release Tablet, Film Coated | Viiv Healthcare |
| Cabotegravir | Vocabria | HIV integrase | Tablet, Film Coated | Viiv Healthcare |
| Vericiguat | Verquvo | sGC | Tablet | Merck Sharp Dohme |
| Levoketoconazole | Recorlev | CYP11B1 CYP11A1 CYP17A1 | Pituitary ACTH Hypersecretion | Strongbridge Dublin Ltd |
| Nirmatrelvir/Ritonavir | Paxlovid | 3CLp HIV-1 protease | Coronavirus Disease 2019 | Pfizer Inc. |
| Tadalafil/Finasteride | TADFIN | PDE5A SRD5A | Prostatic Hyperplasia | Veru Inc |
| Pafolacianine Sodium | Cytalux | FOLR1 | Ovarian Neoplasms | On Target Laboratories Inc |
| Maribavir | Livtencity | UL97 | Cytomegalovirus Infections | Takeda Pharmaceutical Co Ltd |
| Nab-Rapamycin | Fyarro | mTOR | Perivascular Epithelioid Cell Neoplasms | Aadi Bioscience Inc |
| Asciminib | Scemblix | Bcr-Abl | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Novartis Europharm Ltd |
| Fingolimod lauryl sulfate | Tascenso ODT | S1PRs | Multiple Sclerosis | Handa Neuroscience LLC |
| Celecoxib/Tramadol Hydrochloride | COX-2 MOR1 | Acute Pain | Kowa Pharmaceuticals America Inc | |
| Maralixibat | LIVMARLI | IBAT | Alagille Syndrome | Mirum Pharmaceuticals |
| Atogepant | Qulipta | CALCRL | Migraine Disorders | AbbVie |
| Avacopan | Tavneos | C5AR | Granulomatosis with Polyangiitis | Vifor Fresenius Medical Care Renal Pharma France Vifor Sa |
| Mobocertinib | EXKIVITY | EGFR exon 20 insertion mutations | Carcinoma, Non-Small-Cell Lung | Takeda Pharmaceuticals U.S.A. Inc |
| Abrocitinib | Cibinqo | JAK1 | Dermatitis, Atopic | Pfizer Inc. |
| Difelikefalin | KORSUVA | KOR1 | Pruritus | Vifor Fresenius Medical Care Renal Pharma France |
| Belzutifan | WELIREG | EPAS1 | Pancreatic neuroendocrine tumors | Merck & Co Inc |
| Benzoyl Peroxide/Tretinoin | TWIN | RAR-β RAR-γ RAR-α | Acne Vulgaris | Galderma Laboratories Lp |
| Odevixibat | Bylvay | IBAT | Progressive familial intrahepatic cholestasis | Albireo Ab |
| Belumosudil mesylate | Rezurock | ROCK2 | Graft vs Host Disease | Kadmon Corporation Llc |
| Finerenone | Kerendia | MR | Renal Insufficiency, Chronic | Bayer Healthcare Company Ltd. |
| Brincidofovir | TEMBEXA | Virus DNA polymerase | Smallpox | Chimerix Inc |
| Ibrexafungerp | BREXAFEMME | 1,3-beta-glucan synthase | Candidiasis, Vulvovaginal | Scynexis Inc |
| Samidorphan/Olanzapine | Lybalvi | DRD1 DRD2 5-HT2 MOR1 | Bipolar Disorder | Alkermes Inc |
| Leuprolide mesylate | CAMCEVI | GnRH | Prostatic Neoplasms | Accord Healthcare Slu |
| Viloxazine Hydrochloride | Vivalan | NET | Attention Deficit Disorder with Hyperactivity | Supernus Pharmaceuticals Inc |
| Voclosporin | Lupkynis | Calcineurin | Lupus Nephritis | Aurinia Pharmaceuticals Inc |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Vibegron | Gemtesa | ADRB3 | Overactive bladder | Urovant Sciences Gmbh |
| Ansuvimab-zykl | Ebanga | EBOV | Ebola | Ridgeback Biotherapeutics |
| Relugolix | Orgovyx | GnRHR | Prostate cancer | Myovant Sciences Gmbh |
| Margetuximab | Margenza | HER2 | Breast cancer | Macrogenics Inc |
| Tirbanibulin | Klisyri | Tubulin | Actinic keratosis | Athenex Inc |
| Berotralstat | Orladeyo | KLKB1 | Hereditary angioedema | Biocryst Pharmaceuticals Inc |
| Gallium GA-68 PSMA-11 | Gallium Ga 68 Psma-11 | GCPII | Prostate cancer | University Of California, San Francisco Foundation |
| Setmelanotide Acetate | Imcivree | MC4R | Obesity | Rhythm Pharmaceuticals Inc |
| Naxitamab | Danyelza | GD2 | Neuroblastoma | Y-Mabs Therapeutics Inc |
| Lumasiran sodium | Oxlumo | HAO1Small interfering RNA | Hyperoxaluria type 1 | Alnylam Pharmaceuticals Inc |
| Casirivimab/imdevimab | Regen-Cov | Unidentified | Novel coronavirus pneumonia | Regeneron Pharmaceuticals |
| Lonafarnib | Zokinvy | Ftase | Premature aging | Eiger Biopharmaceuticals |
| Mannitol | Bronchitol | Unidentified | Cystic fibrosis | Chiesi Usa Inc |
| Remdesivir | Veklury | RNA-directed RNA polymeraseViral proteins | COVID-19 | Gilead Sciences Inc |
| Atoltivimab/maftivimab/odesivimab-Regeneron Pharmaceuticals | Inmazeb | Not available | Ebola | Regeneron Pharmaceuticals |
| Pralsetinib | Gavreto | RET | Non-small lung cancer | Blueprint Medicines |
| Somapacitan | Sogroya | GHR | Growth hormone | Novo Nordisk Inc |
| Clascoterone | Winlevi | AR | Acne | Cassiopea Spa |
| Satralizumab | Enspryng | IL6RAIL6RB | neuromyelitis optica spectrum disorder | Genentech Inc |
| Viltolarsen | Viltepso | DystroglycanDystrophin pre-mRNA | Duchenne muscular dystrophy | Nippon Shinyaku Co Ltd |
| Oliceridine fumarate | Olinvyk | MOR1 | Acute pain | Trevena Inc |
| Risdiplam | Evrysdi | SMN | Spinal muscular atrophy | Genentech Inc |
| Nifurtimox | Lampit | Unidentified | Chagas disease | Bayer Healthcare PharmaceuticalsBayer Healthcare Pharmaceuticals Inc |
| Belantamab mafodotin | Blenrep | BCMATubulin | Multiple myeloma | GlaxoSmithKline LLC |
| Tafasitamab | Monjuvi (Tafasitamab-Cxix) For Injection | CD19 | Diffuse large B-cell lymphoma | Morphosys Us Inc |
| Abametapir | Xeglyze | Metalloproteases | Head lice | Dr. Reddy’S Laboratories SaHatchtech |
| Cedazuridine/Decitabine | Inqovi | CDADNMT1 | Myelodysplastic syndromes | Otsuka Pharmaceutical Co Ltd |
| Fostemsavir Tromethamine | Rukobia | HIV envelope protein gp120 | HIV | Viiv Healthcare Co |
| Remimazolam Besilate | Byfavo | GABAAR | Sedation | Acacia Pharma Ltd |
| Triheptanoin | Dojolvi | Unidentified | Long-chain fatty acid oxidation disorders | Ultragenyx Pharmaceutical Inc |
| Trastuzumab/Pertuzumab | Phesgo | HER2 | Breast cancer | Genentech Inc |
| Lurbinectedin | Zepzelca | POLR2 | Metastatic small cell lung cancer | Jazz Pharmaceuticals Ireland Ltd |
| Inebilizumab | Uplizna | CD19 | Neuromyelitis optica spectrum disorder | Viela Bio |
| Flortaucipir F 18 | Tauvid | TAU | Alzheimer's disease | Avid Radiopharmaceuticals Inc |
| Artesunate | Artesunate | ATP2A1ATP2A2 | Severe malaria | Amivas (US) LLC |
| Fluoroestradiol F 18 | Cerianna | ERs | Diagnostic imaging agent for certain patients with breast cancer | Zionexa |
| Ripretinib | Qinlock | KITPDGFR-α | Gastrointestinal-stromal tumors | Deciphera Pharmaceuticals Llc |
| Selpercatinib | Retevmo | RET | Lung and thyroid cancers | Loxo Oncology Inc |
| Capmatinib Hydrochloride | Tabrecta | c-Met/HGFR | Non small cell lung cancer | Novartis Pharmaceuticals Corp |
| Daratumumab/Hyaluronidase-fihj | Darzalex Faspro | CD38Hyaluronic acid | Multiple myeloma | Janssen Biotech Inc |
| Opicapone | Ongentys | COMT | Parkinson’s disease | Neurocrine Biosciences Inc |
| Sacituzumab govitecan | Trodelvy | TOP1Trop-2 | Metastatic triple-negative breast cancer | Immunomedics Inc |
| Tucatinib | Tukysa | HER2 | Breast cancer | Seagen Inc |
| Pemigatinib | Pemazyre | FGFR1FGFR2FGFRs | Cholangiocarcinoma | Incyte Corp |
| Selumetinib sulfate | Koselugo | MEK1MEK2 | Neurofibromatosis type 1, | Astrazeneca Pharmaceuticals LP |
| Coagulation factor VIIa (recombinant)-jncw | Sevenfact | F10F9 | Hemophilia A Hemophilia B | Lfb Biotechnologies Sas |
| Ozanimod hydrochloride | Zeposia | S1PRs | Multiple sclerosis | Celgene International Ii Sarl |
| Osilodrostat phosphate | Isturisa | CYP11B1 | Cushing’s disease | Recordati Rare Diseases Inc |
| Isatuximab | Sarclisa | CD38 | Multiple myloma | Sanofi-Aventis U.S. Llc |
| Rimegepant sulfate | Nurtec Odt | CALCRL | Migraine | Biohaven Pharmaceutical Holding Co Ltd |
| Amisulpride | Barhemsys | DRD2DRD3 | Nausea and vomiting after surgery | Acacia |
| Bempedoic Acid/Ezetimibe | Nexlizet | ACLYNPC1L1 | Refractory hypercholesterolemia | Esperion Therapeutics Inc |
| Bempedoic Acid | Nexletol | ACLY | Refractory hypercholesterolemia | Esperion Therapeutics Inc |
| Eptinezumab | Vyepti | CGRP | Migraine | Lundbeck Seattle Biopharmaceuticals Inc |
| Lactitol | Pizensy | Unidentified | Chronic idiopathic constipation | Braintree Laboratories Inc |
| Peanut (Arachis hypogaea) Allergen Powder-dnfp | Palforzia | Not available | Peanut allergenic | Aimmune Therapeutics Inc |
| Tazemetostat Hydrobromide | Tazverik | EZH2 | Epithelioid sarcoma | Epizyme Inc |
| Teprotumumab | Tepezza | IGF1R | Thyroid eye disease | Horizon Therapeutics Ireland |
| Avapritinib | Ayvakit | KITPDGFR-α | Gastrointestinal stromal tumor | Blueprint Medicines |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Ubrogepant | Ubrelvy | CALCRL | Migraine | Allergan Sales Inc |
| Brilliant Blue G | Tissueblue | Unidentified | Ophthalmic surgery | D.O.R.C. Dutch Ophthalmic Research Center (International) Bv |
| Fam-trastuzumab deruxtecan | Enhertu | HER2TOP1 | Breast cancer | Daiichi Sankyo Inc |
| Lumateperone | Caplyta | 5-HT2ADRD2 | Schizophrenia | Intra-Cellular |
| Lemborexant | Dayvigo | OX1ROX2R | Disturbances in initiating and maintaining sleep | Eisai Inc |
| Enfortumab vedotin | Padcev | NECTIN4Tubulin | Bladder cancer Urinary neoplasm | Astellas Pharma Inc |
| Golodirsen | Vyondys 53 | Dystrophin pre-mRNA | Duchenne muscular dystrophy | Sarepta Therapeutics Inc |
| Voxelotor | Oxbryta | Sickle haemoglobin | Sickle cell anemia | Global Blood Therapeutics |
| Cenobamate | Xcopri | GABAARSCNA | Epileptic seizure | Sk Life Science |
| Givosiran | Givlaari | ALAS1Small interfering RNA | Acute intermittent porphyria | Alnylam Pharmaceuticals Inc |
| Crizanlizumab-tmca | Adakveo | SELP | Sickle cell anemia | Novartis Pharmaceuticals Corp |
| Cefiderocol Sulfate Tosylate | Fetroja | PBPs | Urinary system infection | Shionogi Inc |
| Zanubrutinib | Brukinsa | BTK | Mantle cell lymphoma | BeiGene USA, Inc. |
| Luspatercept | Reblozyl | TGF-β | Anemia Β-Mediterranean anemia | Celgene Corp |
| Air polymer-type A | Exem Foam Kit | Unidentified | Infertility | Giskit |
| Diroximel fumarate | Vumerity | Nrf2 | Multiple sclerosis | Biogen Inc |
| Elexacaftor/ivacaftor/tezacaftor | Trikafta (Copackaged) | CFTRPGY1 | Cystic fibrosis | Vertex Pharmaceuticals Incorporated |
| Lasmiditan hemisuccinate | Reyvow | 5-HT1F | Migraine | Eli Lilly and Co |
| Afamelanotide | Scenesse | MCRs | Erythrohepatic protoporphyria | Clinuvel Inc |
| Brolucizumab | Beovu | VEGFA | Age-related macular degeneration | Novartis Pharmaceuticals Corp |
| Trifarotene | Aklief | RAR-γ | Acne vulgaris | Galderma R&D |
| Semaglutide oral (Novo Nordisk) | Rybelsus | GLP1R | Type 2 diabetes mellitus | Novo Nordisk Inc |
| Tenapanor hydrochloride | Ibsrela | NHE3 | Constipation | Ardelyx Inc |
| Istradefylline | Nourianz | ADORA2A | Parkinson’s disease | Kyowa Kirin |
| Edotreotide | Gallium Dotatoc Ga 68 | SSTR2 | Neuroendocrine tumor | Uihc Pet Imaging |
| Lefamulin | Xenleta | 50S ribosomal subunit | PulmonitisCommunity acquired pneumonia | Nabriva Therapeutics |
| Fedratinib | Inrebic | FLT3JAK2 | Myelofibrosis | Impact Pharmaceutical Services Inc |
| Upadacitinib | Rinvoq | JAK1 | Rheumatoid arthritis | Abbvie Inc |
| Entrectinib | Rozlytrek | ALKNTRK2NTRK3ROSTRKA | Non-small cell lung cancerSolid tumor | Genentech Inc |
| Pretomanid | Pretomanid | DNA | Mycobacterium tuberculosis infection | Mylan Ireland Ltd |
| Pitolisant Hydrochloride | Wakix | HRH3 | Narcolepsy | Harmony Biosciences Llc |
| Pexidartinib | Turalio | CSF1RFLT3KIT | Giant cell tumor of tendon sheath | Daiichi Sankyo Inc |
| Darolutamide | Nubeqa | AR | Prostatic cancer | Bayer Healthcare |
| Ferric maltol | Accrufer | Unidentified | Ferropenic anaemia | Shield Tx (Uk) Ltd |
| Amlodipine Benzoate | Katerzia | VDCCs | Hypertension Coronary artery disorder | Silvergate Pharmaceuticals Inc |
| Selinexor | Xpovio | XPO1 | Multiple myeloma | Karyopharm Therapeutics |
| Bremelanotide | Vyleesi (Autoinjector) | MC4R | Psychological sexual dysfunction | Palatin Technologies |
| Insulin human | Myxredlin | INSR | Diabetes mellitus | Baxter Healthcare Corp |
| Polatuzumab vedotin | Polivy | CD79BTubulin | Diffuse large B-cell lymphoma | Genentech Inc |
| Onasemnogene abeparvovec | Zolgensma | SMN | Spinal muscular atrophy | Avexis Inc |
| Alpelisib | Piqray | PI3Kα | Breast cancer | Novartis |
| Amifampridine | Ruzurgi | Potassium channelVGKCs | Lambert-Eaton myasthenic syndrome | Jacobus Pharm Co Inc |
| Tafamidis Meglumine | Vyndaqel | TTR | Heart disorder | Foldrx Pharmaceuticals Inc |
| Risankizumab | Skyrizi | IL23 | Plaque psoriasis | Abbvie Inc |
| Erdafitinib | Balversa | FGFR1FGFR2FGFR3FGFR4 | Transitional cell carcinoma | Janssen Biotech Inc |
| Romosozumab | Evenity | SO | Postmenopausal osteoporosis | Amgen Inc |
| Siponimod | Mayzent | EDG1S1PR5 | Multiple sclerosis | Novartis |
| Solriamfetol | Sunosi | DATNET | Excessive somnolence | Jazz Pharmaceuticals Plc |
| Brexanolone | Zulresso | GABAAR | Depression puerperal | Sage Therapy Group |
| Trastuzumab/Hyaluronidase-oysk | Herceptin Hylecta | HER2Hyaluronic acid | Breast cancer | Genentech Inc |
| Turoctocog alfa pegol | F10 | Hemophilia A | Novo Nordisk Inc | |
| Triclabendazole | Egaten | DNMT1 | Fasciola hepatica infection | Novartis |
| Caplacizumab | Cablivi | vWF | Thrombotic thrombocytopenic purpura | Ablynx Nv |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Tagraxofusp-erzs | Elzonris | IL3RA | Blastic plasmacytoid dendritic cell neoplasm | Stemline Therapeutics Inc |
| Ravulizumab | Ultomiris | C5 | Paroxysmal nocturnal hemoglobinuria | Alexion Pharmaceuticals Inc |
| Calaspargase pegol (Shire) | Asparlas | ASNAmidohydrolasesAspartate-ammonia ligase | Acute lymphoblastic leukemia | Servier Pharmaceuticals Llc |
| Prucalopride Succinate | Motegrity | 5-HT4 | Chronic idiopathic constipation | Takeda Pharmaceuticals U.S.A. Inc |
| Amifampridine Phosphate | Firdapse | Potassium channelVGKCs | Lambert-Eaton myasthenic syndrome | Catalyst Pharmaceuticals Inc |
| Gilteritinib Fumarate | Xospata | AXLFLT3 | Acute myeloid leukemia | Astellas Pharma Inc |
| Larotrectinib sulfate | Vitrakvi | NTRKNTRK2NTRK3TRKA | Solid tumors | Bayer Healthcare |
| Glasdegib | Daurismo | SMO | Acute myeloid leukemia | Pfizer Inc |
| Emapalumab | Gamifant | IFN-γ | Hemophagocytic lymphohistiocytosis | Novimmune Sa |
| Revefenacin | Yupelri | mAChRs | Chronic obstructive pulmonary disease | Mylan Ireland Ltd |
| Lorlatinib | Lorbrena | ALKROS | Non-small cell lung cancer | Pfizer Inc |
| Baloxavir Marboxil | Xofluza | PA | Influenza | Genentech Inc |
| Talazoparib | Talzenna | PARP-2PARP1 | Metastatic breast cancer | Pfizer Inc |
| Elapegademase-lvlr | Revcovi | Adenosine | Adenosine Deaminase-Severe Combined Immunodeficiency | Leadiant Biosciences Inc |
| Inotersen sodium | Tegsedi | Small interfering RNATTR | Polyneuropathy of hereditary transthyretin-mediated amyloidosis | Akcea Therapeutics Inc |
| Omadacycline | Nuzyra | 30S subunit | community-acquired bacterial pneumonia,acute bacterial skin,skin structure infections | Paratek Pharmaceuticals Inc |
| Sarecycline Hydrochloride | Seysara | 30S subunit | Acne vulgaris | Almirall Sa |
| Cemiplimab | Libtayo | PD-1 | Cutaneous squamous cell carcinoma | Regeneron Pharmaceuticals Inc |
| Galcanezumab | Emgality | CGRP | Migraine | Eli Lilly and Co |
| Dacomitinib | Vizimpro | EGFRHER2HER4 | Metastatic non-small-cell lung cancer | Pfizer Inc |
| Duvelisib | Copiktra | PI3KγPI3Kδ | Chronic lymphocytic leukemia, small lymphocytic lymphoma，follicular lymphoma | Secura Bio |
| Fremanezumab | Ajovy | CGRP | Migraine | Teva Pharmaceuticals Usa Inc |
| Moxetumomab pasudotox | Lumoxiti | CD22 | Hairy cell leukemia | Innate Pharma |
| Doravirine | Pifeltro | RT | HIV | Merck & Co Inc |
| Damoctocog alfa pegol | Jivi | F10 | Hemophilia A | Bayer Healthcare |
| Eravacycline Dihydrochloride | Xerava | 30S subunit | Intra-abdominal infections | Tetraphase Pharmaceuticals |
| Lanadelumab | Takhzyro | KLKB1 | Hereditary angioedem | Dyax Corp |
| Cenegermin | Oxervate | NGFR | Neurotrophic keratitis | Dompe Farmaceutici Spa |
| Stiripentol | Diacomit | GABAARL-lactate dehydrogenase A chainL-lactate dehydrogenase B chain | Dravet syndrome | Biocodex Sa |
| Migalastat Hydrochloride | Galafold | α-Gal A | Fabry disease | Amicus Therapeutics Inc |
| Mogamulizumab | Poteligeo | CCR4 | Non-Hodgkin lymphoma | Kyowa Kirin |
| Lusutrombopag | Mulpleta | TpoR | Thrombocytopenia | Shionogi Inc |
| Fish oil triglycerides | Omegaven | Unidentified | As a source of calories and fatty acids in pediatric patients with parenteral nutrition-associated cholestasis | Fresenius Kabi Manufacturing Sa |
| Elagolix Sodium | Orilissa | GnRHR | Endometriosis | Abbvie Inc |
| Tafenoquine Succinate | Krintafel | Unidentified | Plasmodium vivax malaria | GlaxoSmithiline IntellectualProperty DevelopentLtd England |
| Ivosidenib | Tibsovo | IDH1 | Acute myeloid leukemia | Agios Pharmaceuticals Inc |
| Tecovirimat | Tpoxx | env | Smallpox | Siga Technologies Inc |
| Glycopyrrolate Tosylate | Qbrexza | mAChRs | Hyperhidrosis of axilla | Dermira Inc |
| Binimetinib | Mektovi | MEK1MEK2 | Melanoma | Array Biopharma Inc |
| Encorafenib | Braftovi | B-raf | Melanoma | Array Biopharma Inc |
| Cannabidiol | Epidiolex | CB1 | Epilepsy | Gw Research Ltd |
| Plazomicin sulfate | Zemdri | 30S subunit | Urinary tract infections | Cipla Usa Inc |
| Moxidectin | Moxidectin | Glutamate-gated chloride channel | Onchocerciasis | Medicines Development For Global Health Ltd |
| Baricitinib | Olumiant | JAK1JAK2 | Rheumatoid arthritis | Eli Lilly and Co |
| Pegvaliase-pqpz | Palynziq | PAH | Phenylketonuria | Biomarin Pharmaceutical Inc |
| Avatrombopag Maleate | Doptelet | TpoR | Thrombocytopenia | Akarx Inc |
| Sodium zirconium cyclosilicate | Lokelma | Potassium | Hyperkalemia | Astrazeneca Pharmaceuticals LP |
| Erenumab-aooe | Aimovig | CALCRLCGRP | Migraine | Amgen Inc |
| Lofexidine Hydrochloride | Lucemyra | ADRA2 | Opioid withdrawal symptoms | Us Worldmeds Holdings Llc |
| Andexanet alfa | Andexxa | PT | Anticoagulation | Portola |
| Burosumab | Crysvita | FGF23 | x-linked hypophosphatemia | Ultragenyx Pharmaceutical Inc |
| Fostamatinib disodium hexahydrate | Tavalisse | Syk | Immune thrombocytopenia | Rigel Pharmaceuticals Inc |
| Tildrakizumab-asmn | Ilumya | IL23IL23R | Psoriasis | Sun Pharma Global Fze |
| Ibalizumab-uiyk | Trogarzo | CD4Viral fusion proteins | HIV | Taimed Biologics Usa Corp |
| Durvalumab | Imfinzi | PD-L1 | Non-small cell lung cancer | Astrazeneca Uk Ltd |
| Apalutamide | Erleada | AR | Prostate cancer | Janssen Biotech Inc |
| Lutetium (177Lu) oxodotreotide | Lutathera | SSTR2 | Gastroenteropancreatic neuroendocrine tumors | Aaa Usa Inc |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Angiotensin II | Giapreza | AT2 | Low Blood Pressure | La Jolla Pharma Llc |
| Macimorelin Acetate | Macrilen | GHSR | Growth hormone deficiency | Novo Nordisk Inc |
| Voretigene neparvovec-rzyl | Luxturna | RPE65 | Biallelic RPE65 mutation associated retinal dystrophy | Spark Therapeutics Inc |
| Ertugliflozin | Steglatro | SGLT2 | Type 2 diabetes | Merck & Co Inc |
| Netarsudil Dimesylate | Rhopressa | CTGFNETRHOKTGFBR2 | Glaucoma or ocular hypertension | Aerie Pharmaceuticals Inc |
| Cocaine Hydrochloride | Goprelto | AdrenoceptorsSCNA | Anesthesia | Genus Lifesciences Inc |
| Ozenoxacin | Xepi | Bacterial DNA gyraseTopoisomerase IV | Impetigo | Grupo Ferrer Internacional Sa |
| Semaglutide | Ozempic | GLP1R | Type 2 diabetes | Novo Nordisk Inc |
| Emicizumab | Hemlibra | F10F9 | Hemophilia A | Genentech Inc |
| Vestronidase alfa-vjbk | Mepsevii | GAG | Mucopolysaccharidosis type VII | Ultragenyx Pharmaceutical Inc |
| Benralizumab | Fasenra | IL5RA | Asthma | Astrazeneca Ab |
| Letermovir | Prevymis | UL30UL54 | Cytomegalovirus | Merck & Co Inc |
| Latanoprostene Bunod | Vyzulta | PTGFR | Ocular hypertension，Open-angle glaucoma | Bausch And Lomb Inc |
| Acalabrutinib | Calquence | BTK | Mantle cell lymphoma | Astrazeneca UK Ltd |
| Ascorbic Acid | Ascor | Unidentified | Scurvy | Mcguff Pharmaceuticals Inc |
| Abemaciclib | Verzenio | CDK4CDK6 | Breast cancers | Eli Lilly and Co |
| Secnidazole | Solosec | DNA | Bacterial vaginosis | Lupin Inc |
| Copanlisib Hydrochloride | Aliqopa | PI3KαPI3Kδ | Follicular lymphoma | Bayer Healthcare |
| Tisagenlecleucel | Kymriah | CD19 | B-cell acute lymphoblastic leukemia | Novartis Pharmaceuticals Corp |
| Amantadine Hydrochloride | Gocovri | DRDsNMDAR | Dyskinesia | Adamas Pharma Llc |
| Inotuzumab Ozogamicin | Besponsa | CD22DNA | B-cell acute lymphoblastic leukemia | Wyeth-Ayerst Pharmaceuticals Inc |
| Enasidenib Mesylate | Idhifa | IDH2 | B-cell acute lymphoblastic leukemia | Celgene Corp |
| Neratinib Maleate | Nerlynx | EGFRHER2HER4 | Breast cancers | Puma Biotechnology Inc |
| Pitavastatin Magnesium | Zypitamag | HMGCR | Myocardial infarction and stroke | Medicure International Inc |
| Guselkumab | Tremfya | IL-23p19 | Plaque psoriasis | Janssen Biotech Inc |
| Betrixaban | Bevyxxa | F10 | Venous thromboembolism | Portola Pharmaceuticals Inc |
| Hyaluronidase/Rituximab | Rituxan Hycela | CD20Hyaluronic acid | Follicular lymphoma, Diffuse Large B-cell Lymphoma, Chronic Lymphocytic Leukemia | Genentech Inc |
| Delafloxacin | Baxdela | Bacterial DNA gyraseTopoisomerase IV | Acute bacterial skin infections | Melinta Therapeutics Inc |
| Calcium Gluconate | Calcium Gluconate | Unidentified | Hypocalcaemia | Fresenius Kabi Manufacturing Sa |
| Nonacog beta pegol | Rebinyn | F10 | Hemophilia B | Novo Nordisk Inc |
| Sarilumab | Kevzara | IL6RAIL6RB | Rheumatoid arthritis | Sanofi-Synthelabo |
| Edaravone | Radicava | Unidentified | Amyotrophic lateral sclerosis | Mitsubishi Tanabe Pharma Corp |
| Brigatinib | Alunbrig | ALKEGFRFLT3IGF1RROS | Non-small cell lung cancer | Ariad Pharmaceuticals Inc |
| Abaloparatide | Tymlos | PTHR | Osteoporosis in postmenopausal | Radius Health Inc |
| Midostaurin | Rydapt | FLT3KITPDGFR-βPKC-αVEGFR2 | Myeloid leukemia, Systemic mastocytosis | Novartis Pharmaceuticals Corp |
| Cerliponase alfa | Brineura | IGF2R | Batten disease | Biomarin Pharmaceutical Inc |
| Valbenazine Tosylate | Ingrezza | VMAT2 | Tardive dyskinesia | Neurocrine Biosciences Inc |
| Deutetrabenazine | Austedo | VMAT2 | Huntington’s disease | Teva Branded Pharmaceutical Products R&D Inc |
| Ocrelizumab | Ocrevus | CD20 | Multiple sclerosis | Genentech Inc |
| Dupilumab | Dupixent | IL4RA | Moderate-to-severe eczema | Regeneron Pharmaceuticals Inc |
| Niraparib Tosylate | Zejula | PARP-2PARP1 | Recurrent epithelial ovarian, Fallopian tube, Peritoneal cancers | GlaxoSmithKline LLC |
| Naldemedine Tosylate | Symproic | MOR1 | Opioid-induced constipation | Biodelivery Sciences International Inc |
| Avelumab | Bavencio | PD-L1 | Merkel cell carcinoma | Emd Serono Inc |
| Safinamide Methanesulfonate | Xadago | DRDsMAOB | Parkinson’s disease | Us Worldmeds Holdings Llc |
| Ribociclib Succinate | Kisqali | CDK4CDK6 | Breast cancer | Novartis Pharmaceuticals Corp |
| Telotristat Etiprate | Xermelo | TPH1TPH2 | Rarcinoid syndrome diarrhea | Tersera Therapeutics |
| Brodalumab | Siliq | IL17RA | Plaque psoriasis | Valeant Pharmaceuticals Luxembourg Sarl |
| Deflazacort | Emflaza | GR | Duchenne muscular dystrophy | Ptc Therapeutics Inc |
| Etelcalcetide Hydrochloride | Parsabiv | CaSR | Hyperparathyroidism | Kai Pharmaceuticals |
| Plecanatide | Trulance | STAR | Chronic idiopathic constipation | Salix Pharmaceuticals |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Para-Toluenesulfonamide | CA3 CA2 | Carcinoma, Non-Small-Cell Lung | Tianjin Chase Sun Jiankangda | |
| Linperlisib | 因他瑞 | PI3Kδ | Lymphoma, Follicular | Shanghai YL-PHARMA |
| Ansofaxine Hydrochloride | NET DAT SERT | Depressive Disorder | Shandong Luye Pharma | |
| Dorzagliatin | 华堂宁 | GK | Diabetes Mellitus, Type 2 | Hua Medicine |
| Alanylglutamine/Amino acid | Unidentified | Dietary Supplement | Beijing Sciecure Pharmaceutical Co., Ltd. | |
| Rezvilutamide | 艾瑞恩 | AR | Prostatic Neoplasms | Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
| Mitoxantrone liposomal | TOP2 Pim-1 NS3/NS4A | Lymphoma, T-Cell, Peripheral | CSPC Zhongqi Pharmaceutical Co., Ltd. |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Vigabatrin | GABAAR | Epilepsy | Aucta Pharmaceuticals, Inc. | |
| Hyzetimibe | 赛斯美 | NPC1L1 | Hypercholesterolemia | Zhejiang Hisun Pharmaceutical Co., Ltd |
| Ainuovirine | 艾邦德 | HIV-1 RT | HIV infection | Jiangsu Aidea Pharmaceutical Co.,Ltd |
| Tenofovir Amibufenamide | 恒沐 | RT | Chronic hepatitis B | Jiangsu Hansoh Pharmaceutical Group Co., Ltd |
| Savolitinib | 沃瑞沙/ORPATHYS | c-Met/HGFR | Non-small cell lung cancer | Hutchison Medipharma Ltd |
| Risdiplam | 艾满欣 | SMN | Spinal muscular atrophy | Roche |
| Nitisinone | 4HPPD | Tyrosinemia | Chinese Medicines（Guangzhou）Ltd | |
| Herombopag Olamine | 恒曲 | TpoR | Platelets decreased Anemia aplastic aregenerative | Jiangsu Hengrui Pharmaceuticals Co.,Ltd |
| Tetrabenazine | VMAT2 | Huntington’s disease | ||
| Disitamab Vedotin | 爱地希 | HER2Tubulin | Gastric Cancer | RemeGen Co., Ltd. |
| Ipilimumab | 逸沃 | CTLA4 | Melanoma Non-small cell lung cancer | Bristol-Myers Squibb |
| Donafenib Tosylate | 泽普生/ZEPSUN | RAFReceptor protein-tyrosine kinase | Hepatocellular carcinoma | Suzhou Zelgen Biopharmaceuticals Co., Ltd. |
| Contezolid | 优喜泰 | 50S ribosomal subunit | Complex skin and skin structure infections | MicuRx |
| Obinutuzumab | 佳罗华 | CD20 | Follicular center cell lymphoma | Roche |
| (S)-Ornidazole Disodium Phosphate | 新锐 | DNA | Abdominal infection Gingivitis Sepsis | |
| Fospropofol Disodium | GABAAR | Anesthesia | Yichang Humanwell Pharmaceutical Co., Ltd | |
| Pamiparib | 百汇泽 | PARP-2PARP1 | Ovarian cancer Fallopian tube cancer Peritoneal cancer | BeiGene |
| Satralizumab | 安适平 | IL6RAIL6RB | Neuromyelitis optica | Roche |
| Baloxavir Marboxil | 速福达 | PA | Influenza viral infections | Roche |
| Velaglucerase alfa | 维葡瑞 | GlcCer | Gaucher disease | Shire BioScience |
| Semaglutide | 诺和泰 | GLP1R | Type 2 diabetes mellitus | Novo Nordisk |
| Eftrenonacog Alfa | 赛玖凝 | F10 | Hemophilia B | Bioverativ Therapeutics Inc |
| Dimethyl Fumarate | Tecfidera | KEAP1 | Multiple sclerosis | IQVIA |
| Icatibant Acetate | BKR2 | Precursor B-cell lymphoblastic leukemia-lymphoma | Shire Pharmaceuticals | |
| Ripretinib | 擎乐 | KITPDGFR-α | Gastrointestinal stromal tumor | Zai Lab |
| Avapritinib | 泰吉华 | KITPDGFR-α | Gastrointestinal stromal tumor | CStone Pharmaceuticals |
| Pralsetinib | 普吉华 | RET | Non-small cell lung cancer | CStone Pharmaceuticals |
| Utidelone | 优替帝 | Tubulin | Breast cancer | CN-Biostar |
| Telitacicept | 泰爱 | APRILBAFF/BLyS | Systemic lupus erythematosus | RemeGen Co., Ltd. |
| Alflutinib Mesylate | 艾弗沙 | EGFR | Non-small cell lung cancer | Shanghai Allist Pharmaceuticals Co., Ltd |
| Darolutamide | 诺倍戈 | AR | Prostatic cancer | Orion Corp Orion Pharma Espoo |
| Gilteritinib Fumarate | 适加坦 | AXLFLT3 | Acute myelocytic leukaemia | Astellas |
| Azilsartan Medoxomil Potassium | 易达比 | AT1 | Essential hypertension | Takeda Pharmaceuticals |
| Burosumab | 麟平 | FGF23 | X linked inherited disease | Kyowa Kirin |
| Vigabatrin | GABAAR | Epilepsy | Aucta Pharmaceuticals, Inc. | |
| Hyzetimibe | 赛斯美 | NPC1L1 | Hypercholesterolemia | Zhejiang Hisun Pharmaceutical Co., Ltd |
| Ainuovirine | 艾邦德 | HIV-1 RT | HIV infection | Jiangsu Aidea Pharmaceutical Co.,Ltd |
| Tenofovir Amibufenamide | 恒沐 | RT | Chronic hepatitis B | Jiangsu Hansoh Pharmaceutical Group Co., Ltd |
| Savolitinib | 沃瑞沙/ORPATHYS | c-Met/HGFR | Non-small cell lung cancer | Hutchison Medipharma Ltd |
| Risdiplam | 艾满欣 | SMN | Spinal muscular atrophy | Roche |
| Nitisinone | 4HPPD | Tyrosinemia | Chinese Medicines（Guangzhou）Ltd | |
| Herombopag Olamine | 恒曲 | TpoR | Platelets decreased Anemia aplastic aregenerative | Jiangsu Hengrui Pharmaceuticals Co.,Ltd |
| Tetrabenazine | VMAT2 | Huntington’s disease | ||
| Disitamab Vedotin | 爱地希 | HER2 Tubulin | Gastric Cancer | RemeGen Co., Ltd. |
| Ipilimumab | 逸沃 | CTLA4 | Melanoma Non-small cell lung cancer | Bristol-Myers Squibb |
| Donafenib Tosylate | 泽普生/ZEPSUN | RAF Receptor protein-tyrosine kinase | Hepatocellular carcinoma | Suzhou Zelgen Biopharmaceuticals Co., Ltd. |
| Contezolid | 优喜泰 | 50S ribosomal subunit | Complex skin and skin structure infections | MicuRx |
| Obinutuzumab | 佳罗华 | CD20 | Follicular center cell lymphoma | Roche |
| (S)-Ornidazole Disodium Phosphate | 新锐 | DNA | Abdominal infection Gingivitis Sepsis | |
| Fospropofol Disodium | GABAAR | Anesthesia | Yichang Humanwell Pharmaceutical Co., Ltd | |
| Pamiparib | 百汇泽 | PARP-2 PARP1 | Ovarian cancer Fallopian tube cancer Peritoneal cancer | BeiGene |
| Satralizumab | 安适平 | IL6RA IL6RB | Neuromyelitis optica | Roche |
| Baloxavir Marboxil | 速福达 | PA | Influenza viral infections | Roche |
| Velaglucerase alfa | 维葡瑞 | GlcCer | Gaucher disease | Shire BioScience |
| Semaglutide | 诺和泰 | GLP1R | Type 2 diabetes mellitus | Novo Nordisk |
| Eftrenonacog Alfa | 赛玖凝 | F10 | Hemophilia B | Bioverativ Therapeutics Inc |
| Dimethyl Fumarate | Tecfidera | KEAP1 | Multiple sclerosis | IQVIA |
| Icatibant Acetate | BKR2 | Precursor B-cell lymphoblastic leukemia-lymphoma | Shire Pharmaceuticals | |
| Ripretinib | 擎乐 | KIT PDGFR-α | Gastrointestinal stromal tumor | Zai Lab |
| Avapritinib | 泰吉华 | KIT PDGFR-α | Gastrointestinal stromal tumor | CStone Pharmaceuticals |
| Pralsetinib | 普吉华 | RET | Non-small cell lung cancer | CStone Pharmaceuticals |
| Utidelone | 优替帝 | Tubulin | Breast cancer | CN-Biostar |
| Telitacicept | 泰爱 | APRIL BAFF/BLyS | Systemic lupus erythematosus | RemeGen Co., Ltd. |
| Alflutinib Mesylate | 艾弗沙 | EGFR | Non-small cell lung cancer | Shanghai Allist Pharmaceuticals Co., Ltd |
| Darolutamide | 诺倍戈 | AR | Prostatic cancer | Orion Corp Orion Pharma Espoo |
| Gilteritinib Fumarate | 适加坦 | AXL FLT3 | Acute myelocytic leukaemia | Astellas |
| Azilsartan Medoxomil Potassium | 易达比 | AT1 | Essential hypertension | Takeda Pharmaceuticals |
| Burosumab | 麟平 | FGF23 | X linked inherited disease | Kyowa Kirin |
| Dalpiciclib Isethionate | 艾瑞康 | CDK6 CDK4 | Breast Neoplasms | Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
| Henagliflozin Proline | 瑞沁️ | SGLT2 | Diabetes Mellitus, Type 2 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
| Aildenafil Citrate | 爱力士 | PDE5A | Erectile Dysfunction | Youcare Pharmaceutical Group |
| Nirmatrelvir/Ritonavir | Paxlovid | 3CLp HIV-1 protease | Coronavirus Disease 2019 | Pfizer Inc. |
| Olverembatinib | 耐立克 | Bcr-Abl KIT | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Ascentage International Limited |
| Cefotaxime Sodium/Tazobactam Sodium | PBPs Beta Lactamase | Urinary Tract Infections | Nanjing Yoko Bio-Pharma Co., Ltd. | |
| Chiglitazar Sodium | 双洛平 | PPARα PPARγ PPARδ | Diabetes Mellitus, Type 2 | Chengdu Chipscreen Pharmaceutical Co., Ltd |
| Abrocitinib | 希必可 | JAK1 | Dermatitis, Atopic | Pfizer Inc. |
| Azvudine | HIV-1 RT VIF RdRp | Coronavirus Disease 2019 | Henan Zhenzhen Biotechnology Co., Ltd. | |
| Finerenone | 可申达 | MR | Renal Insufficiency, Chronic | Bayer Healthcare Company Ltd. |
| Hyzetimibe | 赛斯美 | NPC1L1 | Hypercholesterolemia | Zhejiang Hisun Pharmaceuticals Co., Ltd. |
| Ainuovirine | 艾邦德 | HIV-1 RT RT | HIV Infections | Jiangsu Aidea Pharmaceutical Co.,Ltd. |
| Tenofovir Amibufenamide | 恒沐 | RT | Hepatitis B, Chronic | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. |
| Savolitinib | 沃瑞沙 | c-Met | Carcinoma, Non-Small-Cell Lung | Hutchmed Limited |
| Herombopag Olamine | 恒曲 | TpoR | Thrombocytopenia | Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
| Donafenib Tosylate | 泽普生 | RPTKs RAF VEGFR PDGFR | Thyroid Neoplasms | Suzhou Zelgen Biopharmaceuticals Co., Ltd. |
| Contezolid | 优喜泰 | 50S ribosomal subunit | Complicated Skin and Soft Tissue Infections | Shanghai MicuRx Pharmaceutical Co., Ltd. |
| 新锐 | Not applicable | Susceptible anaerobic bacteria infection | Zilong Yangzijiang | |
| Pamiparib | 百汇泽 | PARP-2 PARP1 | Ovarian Neoplasms | BeiGene (Beijing) Co., Ltd. |
| Utidelone | 优替帝 | Tubulin | Breast Neoplasms | Chengdu Biostar Technologies, Ltd |
| Alflutinib Mesylate | 艾弗沙 | EGFR T790M | Carcinoma, Non-Small-Cell Lung | Shanghai Allist Pharmaceuticals Co. Ltd. |
| Trilaciclib Dihydrochloride | 科赛拉 | CDK6 CDK4 | Chemotherapy-induced myelosuppression | Simcere Pharmaceutical Group Limited |
| Vericiguat | 唯可同 | sGC | Heart Failure | Bayer Healthcare Company Ltd. |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Abemaciclib | 唯择 | CDK4CDK6 | Breast cancer | Eli Lilly |
| Surufatinib | 苏泰达/SULANDA | CSF1RFGFR1VEGFR2 | Neuroendocrine tumor | HUTCHMED |
| Orelabrutinib | 宜诺凯 | BTK | Chronic lymphocytic leukemia Mantle cell lymphoma | InnoCare |
| Emitasvir Phosphate | 东卫恩 | NS5A | Hepatitis C | Yichang HEC Changjiang Pharmaceutical CO., Ltd |
| Eldecalcitol | VDR | Osteoporosis | Chugai Pharmaceutical | |
| Ciprofol | 思舒宁 | GABAAR | Sedation Anesthesia | Haisco Pharmaceutical |
| Fluzoparib | 艾瑞颐 | PARP | Ovarian cancer Peritoneal carcinoma Fallopian tube cancer | Jiangsu Hengrui Pharmaceuticals Co.,Ltd |
| Lanadelumab | 达泽优 | KLKB1 | Precursor B-cell lymphoblastic leukemia-lymphoma | Catalent Inc |
| Venetoclax | 唯可来 | BCL2 | Acute myelocytic leukaemia | Abbvie |
| Doravirine | 沛卓 | RT | HIV infection | Merck Sharp & Dohme Bv |
| Ensartinib Hydrochloride | 贝美纳 | ALK | Non-small cell lung cancer | Betta Pharmaceuticals Co., Ltd |
| Pomalidomide | COX-2CRBNIL6TNFα | Multiple myeloma | Chia Tai Tianqing Pharmaceutical Group Co., Ltd | |
| Ceftobiprole Medocaril Sodium | PBPs | Hospital acquired pneumonia Community acquired pneumonia | Patheon UK Limited | |
| Botulinum toxin A (Hugel) | SNAP-25 | Nasolabial fold wrinkles | Beijing Four Rings Biopharmaceutical.Co., Ltd. | |
| Idursulfase beta | 海芮思 | GAG | Type II mucopolysaccharidosis | CANbridge Life Sciences Ltd. |
| Radium Ra223 dichloride | DNA | Prostatic cancer | Institute For Energy Technology | |
| Pralatrexate | DHFR | Peripheral T-cell lymphoma | ||
| Agalsidase alfa | 瑞普佳 | α-Gal A | Fabry disease | Vetter Pharma-Fertigung Gmbh & Co Kg |
| Ertugliflozin | 捷诺妥 | SGLT2 | Type 2 diabetes mellitus | Pfizer Manufacturing Deutschland Gmbh |
| Crisaborole | 舒坦明 | PDE4 | Dermatitis atopic | Anacor Pharmaceuticals Inc |
| Edaravone/(+)-2-Decanol | Unidentified | Apoplexy | Simcere Pharmaceutical Group Limited | |
| Ravidasvir Hydrochloride | 新力莱 | NS5A | Hepatitis C | Ascletis Pharma Inc. |
| Remimazolam Besilate | 锐马 | GABAAR | Sedation | Yichang Humanwell Pharmaceutical Co., Ltd |
| Botulinum toxin A (Ipsen) | 吉适 | SNAP-25 | Facial dermatosis | Ipsen Ltd |
| Brodalumab | 立美芙 | IL17RA | Plaque psoriasis | Kyowa Kirin |
| Dupilumab | 达必妥 | IL4RA | Dermatitis atopic | Sanofi-Aventis Group |
| Darbepoetin alfa (Amgen) | 耐斯宝 | EpoR | Anemia | Kyowa Kirin |
| Prulifloxacin | Bacterial DNA gyraseTopoisomerase IV | Urinary system infection | Az. Chim. Riun. Angelini Francesco A.C.R.A.F. Spa | |
| Laronidase | 艾而赞 | DSHS | Type I mucopolysaccharidosis | Genzyme Europe Bv |
| Zanubrutinib | 百悦泽/BRUKINSA | BTK | Chronic lymphocytic leukemia Mantle cell lymphoma | BeiGene |
| Deutetrabenazine | VMAT2 | Huntington’s diseaseTardive dyskinesia | Anesta Llc | |
| Brentuximab vedotin | 安适利 | CD30Tubulin | Anaplastic large cell lymphoma Hodgkin's disease | Bsp Pharmaceuticals Spa |
| Siponimod | 万立能 | EDG1S1PR5 | Multiple sclerosis | Novartis Pharma Stein Ag |
| Neratinib Maleate | 贺俪安 | EGFRHER2HER4 | Breast cancer | |
| Avatrombopag Maleate | 苏可欣 | TpoR | Liver disorder Platelets decreased | Eisai |
| Recombinant Mycobacterium Tuberculosis Fusion Protein(EC) | 宜卡 | Not available | Diagnostic agent Mycobacterium tuberculosis infection | Anhui Zhifei Longcom Biopharmaceutical Co.,Ltd |
| Bencycloquidium Bromide | 必立汀 | CHRM1CHRM3 | Allergic rhinitis | Yingu Pharmaceutical Co., Ltd |
| Almonertinib Mesilate | 阿美乐 | EGFR | Non-small cell lung cancer | Jiangsu Hansoh Pharmaceutical Group Co., Ltd |
| Vedolizumab | 安吉优 | ITGA4&ITGB7 | Crohn's disease Ulcerative colitis | Takeda Pharma A/S |
| Sivelestat Sodium Hydrate | ELANE | Acute lung injury | Huilun | |
| Ustekinumab | 喜达诺 | IL12IL23 | Plaque psoriasis | Jassen-Cilag International Nv |
| Favipiravir | RNA-directed RNA polymerase | Influenza viral infections | Zhejiang Hisun Pharmaceutical Co., Ltd | |
| Coblopasvir hydrochloride | 凯力唯 | NS5A | Hepatitis C | Beijing Kawin Technology Share-Holding Co., Ltd |
| Atezolizumab | 泰圣奇 | PD-L1 | Small cell lung cancer | Roche Registration Gmbh |
| Tafamidis Meglumine | 维达全 | TTR | Amyloid polyneuropathy Transthyretin amyloidosis | Pfizer Europe Ma Eeig |
| Ado-trastuzumab emtansine | 赫赛莱 | HER2Tubulin | Breast cancer | Roche Pharma (Schweiz) Ag |
| SCH 731 BR | Unidentified | |||
| Abatacept | 恩瑞舒 | CD80CD86 | Rheumatoid arthritis | Bristol-Myers Squibb |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Sodium zirconium cyclosilicate | 利倍卓 | Potassium | Hyperkalemia | Astrazeneca Ab |
| Umeclidinium Bromide | CHRM1CHRM2CHRM3CHRM4CHRM5 | Chronic obstructive pulmonary disease | Glaxo Group Ltd | |
| Alirocumab | 波立达 | PCSK9 | Hypercholesterolemia Atherosclerosis Dyslipidemia | Sanofi-Aventis Groupe |
| Remimazolam Tosylate | 瑞倍宁 | GABAAR | Hyperemesis gravidarum | Jiangsu Hengrui Pharmaceuticals Co.,Ltd |
| Guselkumab | 特诺雅 | IL-23p19 | Psoriasis | Jassen-Cilag International Nv |
| Tislelizumab | 百泽安 | PD-1 | Hodgkin’s disease | BeiGene |
| Niraparib Tosylate | 则乐 | PARP-2PARP1 | Ovarian cancer | Zai Lab |
| Agalsidase beta | 法布赞 | Glycosphingolipid | Fabry disease | Genzyme Europe Bv |
| Trametinib Dimethyl Sulfoxide | 迈吉宁 | MEK1MEK2 | Neoplasm | Novartis Europharm Ltd |
| Dabrafenib Mesylate | 泰菲乐 | B-rafC-Raf | Melanoma | Novartis Europharm Ltd |
| Vonoprazan Fumarate | 沃克 | H+/K+ ATPaseProton pump | Peptic oesophagitis | Takeda Pharmaceutical Co Ltd |
| Durvalumab | 英飞凡 | PD-L1 | Non-small cell lung cancer | Astrazeneca Uk Ltd |
| Flumatinib Mesylate | 豪森昕福 | Bcr-Abl | Chronic myelocytic leukaemia | Jiangsu Hansoh Pharmaceutical Group Co., Ltd |
| Enzalutamide | 安可坦 | AR | Prostatic cancer | Astellas Pharma Europe Ltd |
| Sodium Oligomannurarate | 九期一 | APP | Alzheimer’s disease | Green Valley |
| Fosaprepitant Dimeglumine | NK1R | Nausea Vomiting | Jiangsu Hansoh Pharmaceutical Group Co., Ltd | |
| Perampanel Hydrate | 卫克泰 | AMPAR | Epilepsy | Eisai Europe Ltd |
| Isophane Protamine Recombinant Human Insulin (Hefei Tianmai Biotechnology) | INSR | Diabetes mellitus | Hefei Tianmai Biotechnology Development Co., Ltd. | |
| Apalutamide | 安森珂 | AR | Castration-resistant prostate cancer | Jassen-Cilag International Nv |
| Ixekizumab | 拓咨 | IL17A | Psoriasis | Eli Lilly |
| Garenoxacin Mesylate Hydrate | Bacterial DNA gyraseTopoisomerase IV | Bacterial infection Respiratory tract infection | FUJIFLM Toyama Chemical Co., Ltd | |
| Belimumab | 倍力腾 | BAFF/BLyS | Systemic lupus erythematosus | Glaxosmithkline (Ireland) Ltd |
| Fingolimod Hydrochloride | 捷灵亚®捷灵亚 | EDG1EDG3EDG5EDG6 | Multiple sclerosis | Novartis Pharma Schweiz Ag |
| Eribulin Mesylate | Tubulin | Breast cancer | Eisai Europe Ltd | |
| Daratumumab | 兆珂 | CD38 | Multiple myeloma | Jassen-Cilag International Nv |
| Certolizumab pegol | 希敏佳 | TNFα | Rheumatoid arthritis | Ucb Pharma Sa |
| Baricitinib | 艾乐明 | JAK1JAK2 | Rheumatoid arthritis | Eli Lilly Nederland Bv |
| Carrimycin | 必特 | 50S ribosomal subunit | Bacterial infection | Shanghai Tonglian Pharmaceuticals Co., Ltd. |
| Benvitimod | 欣比克 | AHRCytokine receptors | Psoriasis | Guangdong Zhonghao Pharmaceutical Co., Ltd |
| Camrelizumab | 艾瑞卡 | PD-1 | Hodgkin’s disease | Suzhou Suncadia Biopharmaceuticals Co., Ltd |
| Elosulfase alfa | 唯铭赞 | CSPGsKeratan sulfate | Type IV mucopolysaccharidosis | Biomarin International Ltd |
| Insulin degludec/Insulin aspart | 诺和佳 | INSR | Diabetes mellitus | Novo Nordisk |
| Denosumab | 安加维 | RANKL | Postmenopausal osteoporosis | Amgen |
| Dacomitinib | 多泽润 | EGFRHER2HER4 | Non-small cell lung cancer | Pfizer Europe Ma Eeig |
| Tenofovir Alafenamide Fumarate | RT | Hepatitis B | Patheon | |
| PEG-Loxenatide | 孚来美 | GLP1R | Type 2 diabetes mellitus | Jiangsu Hansoh Pharmaceutical Group Co., Ltd |
| Perfluoropropane-albumin microsphere injection (Nanfang Hospital) | Unidentified | Contrast agent | LZ Pharma | |
| Secukinumab | 可善挺 | IL17A | Plaque psoriasis | Novartis Pharma Schweiz Ag |
| Dulaglutide | 度易达 | GLP1R | Type 2 diabetes mellitus | Eli Lilly Nederland Bv |
| Nusinersen sodium | SMNSmall interfering RNA | Neuromuscular disorder | Biogen Idec Ltd | |
| Tedizolid Phosphate | 赛威乐 | 50S ribosomal subunit | Skin and skin structure infections | Merck Sharp & Dohme Bv |
| Sitafloxacin Hydrate | Bacterial DNA gyraseTopoisomerase IV | Infectious diseases | Daiichi Sankyo | |
| Lurasidone Hydrochloride | 罗舒达 | 5-HT1A5-HT2A5-HT7DRD2 | Schizophrenia | Sunovion Pharmaceuticals Inc |
| Linaclotide | 令泽舒 | NPR3 | Constipation Irritable bowel syndrome | Almac Pharma Services |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Edoxaban Tosilate Hydrate | 里先安 | F10 | Venous thromboembolism Pulmonary embolism | Daiichi Sankyo Europe Gmbh |
| Sintilimab | 达伯舒 | PD-1 | Hodgkin’s disease | Innovent Biologics Inc. |
| Roxadustat | 爱瑞卓 | HIF-PHs | Anemia | FibroGen |
| Pertuzumab | 帕捷特 | HER2 | Breast cancer | Roche Pharma (Schweiz) Ag |
| Toripalimab | 拓益 | PD-1 | Melanoma | Shanghai Junshi Biosciences Co., Ltd. |
| Bendamustine Hydrochloride | 存达 | DNA | B-cell lymphoma | Cephalon Inc |
| Selexipag | 优拓比 | PTGIR | Pulmonary arterial hypertension | Actelion Pharmaceuticals Ltd |
| Emicizumab | 舒友立乐 | F10F9 | Hemophilia A | Roche |
| Plerixafor | 释倍灵 | CXCR4 | Multiple myeloma Non-Hodgkin’s lymphoma | Genzyme Europe Bv |
| Lacosamide | 维派特 | NMDARSCNA | Epilepsy | Ucb Pharma Sa |
| Olodaterol Hydrochloride | ADRB2 | Chronic obstructive pulmonary disease | Boehringer Ingelheim International Gmbh | |
| Degarelix Acetate | GnRHR | Prostatic cancer | Ferring Pharmaceuticals A/S | |
| Fruquintinib | 爱优特 英文：Elunate爱优特/Elunate | VEGFR1VEGFR2VEGFR3 | Colorectal carcinoma | HUTCHMED |
| Flutrimazole | CYP51A1 | Fungal infection | Jiangsu Farever Pharma Co., Ltd | |
| Febuxostat | XO | Gout Hyperuricemia | Teijin Pharma | |
| Eculizumab | 舒立瑞 | C5 | Paroxysmal nocturnal hemoglobinuria Atypical hemolytic uremic syndrome | Alexion Europe Sas |
| Lenvatinib Mesylate | 乐卫玛 | FGFR1FGFR2FGFR3FGFR4KITPDGFR-αRETVEGFR1VEGFR2VEGFR3 | Hepatocellular carcinoma | Eisai Europe Ltd |
| Olaparib | 利普卓 | PARP-2PARP-3PARP1 | Ovarian cancer | Astrazeneca Ab |
| Pyrotinib Maleate | 艾瑞妮 | EGFRHER2HER4 | Breast cancer | Jiangsu Hengrui Pharmaceuticals Co.,Ltd |
| Alectinib Hydrochloride | 安圣莎 | ALKRET | Lung cancer | Roche Registration Gmbh |
| Perflubutane | 示卓安 | Unidentified | Contrast agent | Ge Healthcare As |
| Evolocumab | 瑞百安 | PCSK9 | Atherosclerosis Homozygous familial hypercholesterolemia | Amgen |
| Palbociclib | 爱博新 | CDK4CDK6 | Breast cancer | Pfizer Europe Ma Eeig |
| Pembrolizumab | 可瑞达 | PD-1 | Melanoma | Merck |
| Teriflunomide | 奥巴捷 | DHODH | Multiple sclerosis | Sanofi Us Services Inc |
| Peginterferon SA (Beijing Kawin Technology) | 派益生 | IFNAR | Hepatitis C | Beijing Kawin Technology Share-Holding Co., Ltd. |
| Nivolumab | 欧狄沃 | PD-1 | Non-small cell lung cancer | Bristol-Myers Squibb Pharma Eeig |
| Danoprevir Sodium | 戈诺卫 | NS3/NS4A | Hepatitis C | Ascletis Pharma Inc. |
| Idarucizumab | 泰毕安 | PT | Hemorrhage | Boehringer Ingelheim International Gmbh |
| Rotigotine | 优普洛 | DRD2DRD3 | Parkinson's disease Restless legs syndrome | Ucb Pharma Sa |
| Ceritinib | 赞可达 | ALKIGF1RINSRROS | Non-small cell lung cancer | Novartis Europharm Ltd |
| Albuvirtide | 艾可宁 | gp41 | HIV infection | Frontier Biotechnologies Inc. |
| Anlotinib Dihydrochloride | 福可维 | FGFR1FGFR2FGFR3KITPDGFR-βVEGFR1VEGFR2VEGFR3 | Non-small cell lung cancer | Chia Tai Tianqing Pharmaceutical Group Co., Ltd |
| Recombinant human insulin (Hefei Tianmai Biotechnology) | INSR | Diabetes mellitus | Hefei Tianmai Biotechnology Development Co., Ltd. | |
| Methoxy polyethylene glycol-epoetin beta | 美信罗 | EpoR | Anemia | Roche Pharma (Schweiz) Ag |
| Ixazomib Citrate | 恩莱瑞 | Proteasome | Multiple myeloma | Takeda Pharma A/S |
| Recombinant cytokine gene derived protein (Genova Biotech) | 乐复能；Novaferon | IFNAR | Hepatitis B | Beijing Genova Biotech Co.,Ltd. |
| Delamanid | 德尔巴 | DNA | Multidrug-resistant pulmonary tuberculosis | Otsuka Pharmaceutical Co Ltd |
| Aflibercept | 艾力雅 | PGFVEGFA | Macular oedema Age-related macular degeneration | Bayer Australia Ltd |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Sodium ilaprazole | 壹丽安 | Proton pump | Peptic ulcer | Livzon Pharmaceutical Group Inc. |
| Golimumab | 欣普尼 | TNFα | Ankylosing spondylitis Rheumatoid arthritis | Janssen Biologics Bv |
| Eltrombopag Diolamine | 瑞弗兰 | TpoR | Idiopathic thrombocytopenic purpura | Novartis Pharma Schweiz Ag |
| Modafinil | 伟大 | DAT | Somnolence Hypersomnolence | Welman Phamaceutical |
| Vortioxetine Hydrobromide | 心达悦 | 5-HT1A5-HT1B5-HT1D5-HT35-HT7SERT | Major depressive disorder | Lundbeck Pharmaceutical |
| Diquafosol Tetrasodium | 丽爱思 | P2RY2 | Xerophthalmia | Santen Pharmaceutical Co Ltd |
| Lixisenatide | 利时敏 | GLP1R | Type 2 diabetes mellitus | Sanofi-Aventis Groupe |
| Mirabegron | 贝坦利 | ADRB3 | Overactive bladder | Astellas Pharma Europe Bv |
| Canagliflozin Hemihydrate | 怡可安 | SGLT2 | Type 2 diabetes mellitus | Jassen-Cilag International Nv |
| Macitentan | 傲朴舒 | ETARETBR | Pulmonary arterial hypertension | Actelion Pharmaceuticals Ltd |
| Dasabuvir Sodium Hydrate | 易奇瑞 | NS5B | Chronic hepatitis C | Abbvie Ag |
| Sofosbuvir | 索华迪 | NS5B | Chronic hepatitis C | Gilead Sciences Inc |
| Riociguat | 安吉奥 | sGC | Pulmonary arterial hypertension | Bayer Healthcare Pharmaceuticals |
| Empagliflozin | 欧唐静 | SGLT2 | Type 2 diabetes mellitus | Boehringer Ingelheim International Gmbh |
| Insulin degludec | 诺和达 | INSR | Type 2 diabetes mellitus | Novo Nordisk |
| Nintedanib Esylate | 维加特 | FGFR1FGFR2FGFR3FLT3PDGFR-αPDGFR-βVEGFR1VEGFR2VEGFR3 | Idiopathic pulmonary fibrosis | Boehringer Ingelheim International Gmbh |
| Amisulpride | 索里昂 | DRD2DRD3 | Schizophrenia | Sanofi-Aventis France Sa |
| Omalizumab | 茁乐 | IgE | Asthma | Novartis Europharm Ltd |
| Simeprevir Sodium | 奥莱森 | NS3/NS4A | Hepatitis C | Jassen-Cilag International Nv |
| Ibrutinib | 亿珂 | BTK | Chronic lymphocytic leukemia Mantle cell lymphoma | Pharmacyclics Llc |
| Rasagiline Mesylate | 安齐来 | MAOB | Parkinson’s disease | Teva Pharmaceutical |
| Asunaprevir | 速维普 | NS3/NS4A | Hepatitis C | Bristol-Myers Squibb (Singapore) Pte Ltd |
| Daclatasvir Dihydrochloride | 百立泽 | NS5A | Hepatitis C | Bristol-Myers Squibb (Singapore) Pte Ltd |
| Sugammadex Sodium | 布瑞亭 | Unidentified | Neuromuscular blockade reversal | Merck Sharp & Dohme Ltd |
| Azacitidine | 维达莎 | DNMT1 | Chronic myelocytic leukaemiaMyelodysplastic syndrome Acute myelocytic leukemia | Celgene Europe Bv |
| Recombinant Teriparatide（Shanghai United Cell ） | 珍固 | PTHR | Osteoporosis | Shanghai United Cell Biotechnology Co., Ltd. |
| Osimertinib Mesylate | 泰瑞沙 | EGFR | Non-small cell lung cancer | Astrazeneca Ab |
| Regorafenib Monohydrate | 拜万戈 | ABL1B-rafC-RafCSF1RDDR2EphA2FGFR1FGFR2KITPDGFR-αPDGFR-βRETTIE2TRKAVEGFR1VEGFR2VEGFR3 | Hepatocellular carcinoma Colorectal carcinoma | Bayer Pharma Ag |
| Vemurafenib | 佐博伏 | B-raf | Melanoma | Roche Registration Gmbh |
| Dapagliflozin Propanediol Monohydrate | 安达唐 | AMPKPGY1SGLT2 | Type 2 diabetes mellitus | Astrazeneca Ab |
| Ruxolitinib Phosphate | 捷恪卫 | JAK1JAK2 | Myelofibrosis Essential thrombocythemia Polycythemia vera | Novartis Europharm Ltd |
| Blonanserin | 洛珊 | 5-HT2ADRD2 | Schizophrenia | Sumitomo Dainippon Pharma Co Ltd |
| Afatinib Dimaleate | 吉泰瑞 | EGFRHER2HER4 | Non-small cell lung cancer | Boehringer Ingelheim International Gmbh |
| Pazopanib Hydrochloride | 维全特 | B-rafCSF1RFGFR1FGFR3ITKKITLCKPDGFR-αPDGFR-βVEGFR1VEGFR2VEGFR3 | Renal cell carcinoma | Novartis Pharma Schweiz Ag |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Ensitrelvir | エンシトレルビル フマル酸 | 3CLp | Coronavirus | Shionogi & Co., Ltd. |
| Valemetostat | バレメトスタット バレメトスタットトシル酸塩; | EZH2 EZH1 | Leukemia-Lymphoma, | Daiichi Sankyo Company Limited |
| Deucravacitinib | デュークラバシチニブ | TYK2 | Psoriasis | Bristol-Myers Squibb Kk |
| Darinaparsin | ダリナパルシン ダルビアス | Reactive oxygen species | Lymphoma, | Solasia Pharma Kk |
| Vutrisiran | ブトリシランナトリウム | TTR | Transthyretin | Alnylam Japan Kk |
| Tirzepatide | チルゼパチド | GLP1R GIPR | Diabetes | Eli Lilly Japan Kk |
| Fosnetupitant | ホスネツピタント | NK1R | Chemotherapy-induced | Taiho Pharmaceutical Co.,Ltd. |
| Carotegrast methyl | カロテグラストメチル; | ITGA4&ITGB1 ITGA4&ITGB7 | Colitis, | EA Pharma Co.,Ltd. |
| Gefapixant Citrate | ゲーファピキサントクエン酸塩 | P2RX3 | Cough | Merck |
| Clazosentan Sodium | Pivlaz | ETAR | Brain | Idorsia Pharmaceuticals Ltd |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Chidamide | ハイヤスタ錠10mg | HDAC | T-cell leukemia | Shenzhen Micro Chip Biotechnology Co., Ltd |
| Erenumab-aooe | アイモビーグ皮下注70mgペン | CALCRLCGRP | Migraine | Amgen |
| Imeglimin hydrochloride | PRKAB1 | Type 2 diabetes mellitus | Sumitomo Dainippon Pharma Co Ltd | |
| Givosiran | ギブラーリ皮下注189mg | ALAS1Small interfering RNA | Porphyria hepatic | Alnylam Japan Kk |
| Tazemetostat Hydrobromide | タズベリク錠200mg | EZH2 | Sarcoma | Eisai Corporation |
| Lutetium (177Lu) oxodotreotide | ルタテラ静注 | SSTR2 | Neuroendocrine tumor | Fujifilm Toyama Chemical Co. Ltd |
| Fremanezumab | アジョビ皮下注225mgシリンジ | CGRP | Migraine | Otsuka Pharmaceuticals |
| Dinutuximab | ユニツキシン点滴静注17.5mg/5mL | GD2 | Neuroblastoma | Ohara Pharmaceutical Co., Ltd |
| Risdiplam | エブリスディドライシロップ60mg | SMN | Spinal muscular atrophy | Chandai Pharmaceutical Co. Ltd |
| Vericiguat | ベリキューボ錠2.5mgベリキューボ錠5mgベリキューボ錠10mg | sGC | Heart failure | Bayer Yakuhin Ltd |
| Teduglutide | レベスティブ皮下注用3.8mg | GLP2R | Short-bowel syndrome | Takeda Pharmaceutical |
| Upacicalcet | ウパシタ静注透析用200μgシリンジウパシタ静注透析用250μgシリンジウパシタ静注透析用300μgシリンジウパシタ静注透析用50μgシリンジウパシタ静注透析用25μgシリンジウパシタ静注透析用100μgシリンジウパシタ静注透析用150μgシリンジ | CaSR | Hyperparathyroidism | Sanwa Institute of Chemistry |
| Inebilizumab | ユプリズナ点滴静注100mg | CD19 | Neuromyelitis optica | 田边三菱制药株式会社Mitsubishi Tanabe Pharmaceutical Co. Ltd |
| Pemigatinib | ペマジール錠4.5mg | FGFR1FGFR2FGFRs | Biliary tract carcinoma | Incyte Corp |
| Lisocabtagene maraleucel (Celgene/Juno Therapeutics) | CD19 | Diffuse large B-cell lymphoma Follicular center cell lymphoma | Celgene Corp | |
| Fluciclovine F 18 | Unidentified | Prostatic cancer | Nihon Medi-Physics | |
| Follitropin delta | レコベル皮下注36µgペンレコベル皮下注12µgペンレコベル皮下注72µgペン | FSHR | Infertility | Ferring |
| Osilodrostat phosphate | CYP11B1 | Cushing's syndrome | Recordati Rare Diseases | |
| Abaloparatide | PTHR | Postmenopausal osteoporosis | Teijin | |
| Polatuzumab vedotin | ポライビー点滴静注用30mgポライビー点滴静注用140mg | CD79BTubulin | Diffuse large B-cell lymphoma | F. Hoffmann-La Roche Ag |
| Diclofenac etalhyaluronate | ジョイクル関節注30mg | COXs | Osteoarthritis | Seikagaku |
| Larotrectinib sulfate | NTRKNTRK2NTRK3TRKA | Solid tumor | Bayer Yakuhin Ltd | |
| Galcanezumab | エムガルティ皮下注120mgシリンジエムガルティ皮下注120mgオートインジェクター | CGRP | Migraine | Eli lillyEli Lilly |
| Simoctocog alfa | ヌーイック静注用500ヌーイック静注用4000ヌーイック静注用3000ヌーイック静注用2000ヌーイック静注用250ヌーイック静注用1000ヌーイック静注用2500 | F10 | Hemophilia A | Orcotfarma AB Fujimoto Pharmaceuticals |
| Brigatinib | アルンブリグ錠30mgアルンブリグ錠90mg | ALKEGFRFLT3IGF1RROS | Non-small cell lung cancer | Takeda |
| Dimethyl Sulfoxide | ジムソ膀胱内注入液50% | Unidentified | Cystitis interstitial | Kyorin Pharmaceutical Co Ltd |
| Somapacitan | ソグルーヤ皮下注10mgソグルーヤ皮下注5mg | GHR | Growth hormone absent | Novo Nordisk |
| Idursulfase beta | ヒュンタラーゼ脳室内注射液 15 mg | GAG | Type II mucopolysaccharidosis | Clinigen Inc |
| Molidustat Sodium | マスーレッド錠5mg | HIF-PHs | Chronic renal insufficiency Anemia | Bayer |
| Berotralstat | オラデオカプセル150mg | KLKB1 | Precursor B-cell lymphoblastic leukemia-lymphoma | Orphanpacific |
| Acalabrutinib | カルケンスカプセル100mg | BTK | Lymphocytic leukemia | Astrazeneca Sa |
| Chidamide | ハイヤスタ錠10mg | HDAC | T-cell leukemia | Shenzhen Micro Chip Biotechnology Co., Ltd |
| Erenumab-aooe | アイモビーグ皮下注70mgペン | CALCRL CGRP | Migraine | Amgen |
| Imeglimin hydrochloride | PRKAB1 | Type 2 diabetes mellitus | Sumitomo Dainippon Pharma Co Ltd | |
| Givosiran | ギブラーリ皮下注189mg | ALAS1 Small interfering RNA | Porphyria hepatic | Alnylam Japan Kk |
| Tazemetostat Hydrobromide | タズベリク錠200mg | EZH2 | Sarcoma | Eisai Corporation |
| Lutetium (177Lu) oxodotreotide | ルタテラ静注 | SSTR2 | Neuroendocrine tumor | Fujifilm Toyama Chemical Co. Ltd |
| Fremanezumab | アジョビ皮下注225mgシリンジ | CGRP | Migraine | Otsuka Pharmaceuticals |
| Dinutuximab | ユニツキシン点滴静注17.5mg/5mL | GD2 | Neuroblastoma | Ohara Pharmaceutical Co., Ltd |
| Risdiplam | エブリスディドライシロップ60mg | SMN | Spinal muscular atrophy | Chandai Pharmaceutical Co. Ltd |
| Vericiguat | ベリキューボ錠2.5mg ベリキューボ錠5mg ベリキューボ錠10mg | sGC | Heart failure | Bayer Yakuhin Ltd |
| Teduglutide | レベスティブ皮下注用3.8mg | GLP2R | Short-bowel syndrome | Takeda Pharmaceutical |
| Upacicalcet | ウパシタ静注透析用200μgシリンジ ウパシタ静注透析用250μgシリンジ ウパシタ静注透析用300μgシリンジ ウパシタ静注透析用50μgシリンジ ウパシタ静注透析用25μgシリンジ ウパシタ静注透析用100μgシリンジ ウパシタ静注透析用150μgシリンジ | CaSR | Hyperparathyroidism | Sanwa Institute of Chemistry |
| Inebilizumab | ユプリズナ点滴静注100mg | CD19 | Neuromyelitis optica | 田边三菱制药株式会社 Mitsubishi Tanabe Pharmaceutical Co. Ltd |
| Pemigatinib | ペマジール錠4.5mg | FGFR1 FGFR2 FGFRs | Biliary tract carcinoma | Incyte Corp |
| Lisocabtagene maraleucel (Celgene/Juno Therapeutics) | CD19 | Diffuse large B-cell lymphoma Follicular center cell lymphoma | Celgene Corp | |
| Fluciclovine F 18 | Unidentified | Prostatic cancer | Nihon Medi-Physics | |
| Follitropin delta | レコベル皮下注36µgペン レコベル皮下注12µgペン レコベル皮下注72µgペン | FSHR | Infertility | Ferring |
| Osilodrostat phosphate | CYP11B1 | Cushing's syndrome | Recordati Rare Diseases | |
| Abaloparatide | PTHR | Postmenopausal osteoporosis | Teijin | |
| Polatuzumab vedotin | ポライビー点滴静注用30mg ポライビー点滴静注用140mg | CD79B Tubulin | Diffuse large B-cell lymphoma | F. Hoffmann-La Roche Ag |
| Diclofenac etalhyaluronate | ジョイクル関節注30mg | COXs | Osteoarthritis | Seikagaku |
| Larotrectinib sulfate | NTRK NTRK2 NTRK3 TRKA | Solid tumor | Bayer Yakuhin Ltd | |
| Galcanezumab | エムガルティ皮下注120mgシリンジ エムガルティ皮下注120mgオートインジェクター | CGRP | Migraine | Eli lilly Eli Lilly |
| Simoctocog alfa | ヌーイック静注用500 ヌーイック静注用4000 ヌーイック静注用3000 ヌーイック静注用2000 ヌーイック静注用250 ヌーイック静注用1000 ヌーイック静注用2500 | F10 | Hemophilia A | Orcotfarma AB Fujimoto Pharmaceuticals |
| Brigatinib | アルンブリグ錠30mg アルンブリグ錠90mg | ALK EGFR FLT3 IGF1R ROS | Non-small cell lung cancer | Takeda |
| Dimethyl Sulfoxide | ジムソ膀胱内注入液50% | Unidentified | Cystitis interstitial | Kyorin Pharmaceutical Co Ltd |
| Somapacitan | ソグルーヤ皮下注10mg ソグルーヤ皮下注5mg | GHR | Growth hormone absent | Novo Nordisk |
| Idursulfase beta | ヒュンタラーゼ脳室内注射液 15 mg | GAG | Type II mucopolysaccharidosis | Clinigen Inc |
| Molidustat Sodium | マスーレッド錠5mg | HIF-PHs | Chronic renal insufficiency Anemia | Bayer |
| Berotralstat | オラデオカプセル150mg | KLKB1 | Precursor B-cell lymphoblastic leukemia-lymphoma | Orphanpacific |
| Acalabrutinib | カルケンスカプセル100mg | BTK | Lymphocytic leukemia | Astrazeneca Sa |
| Nirmatrelvir/Ritonavir | Paxlovid | 3CLp HIV-1 protease | Coronavirus | Pfizer Inc. |
| Molnupiravir | Lagevrio | RdRp | Coronavirus | Cipla |
| Asciminib | アシミニブ塩酸塩 | Bcr-Abl | Leukemia, | Novartis Europharm Ltd |
| Difamilast | モイゼルト | PDE4 | Dermatitis, | Otsuka Pharmaceuticals |
| Avacopan | アバコパン タブネオスカプセル | C5AR | Granulomatosis | Vifor Fresenius Medical Care Renal Pharma France Vifor Sa |
| Abrocitinib | アブロシチニブ | JAK1 | Dermatitis, | Pfizer Inc. |
| Finerenone | フィネレノン | MR | Renal | Bayer Healthcare Company Ltd. |
| Sotorasib | ソトラシブ | KRAS G12C | Carcinoma, | Amgen |
| Anamorelin Hydrochloride | アナモレリン塩酸塩 | GHSR | Cachexia | Ono Pharmaceutical |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Niraparib Tosylate | ゼジューラカプセル100㎎ | PARP-2PARP1 | Ovarian cancer | Takeda |
| Sofpironium Bromide | エクロックゲル5% | AChR | Hyperhidrosis | Kaken Pharmaceutical Co Ltd |
| Filgotinib Maleate | ジセレカ錠200mg | JAK1 | Rheumatoid arthritis | Gilead Sciences Inc |
| Cetuximab sarotalocan | アキャルックス点滴静注250mg | EGFR | Head and neck cancer | Rakuten Medical |
| Enarodustat | エナロイ錠2mg | HIF-PHs | Anemia | Japan Tobacco (Hong Kong) Limited |
| Botulinum toxin A (Merz Pharma) | ゼオマイン筋注用200単位ゼオマイン筋注用50単位ゼオマイン筋注用100単位 | SNAP-25 | Spasticity of upper and lower extremities | Teijin |
| Daprodustat | ダーブロック錠1mg | ErythropoiesisHIF-PHs | Anemia | GlaxoSmithKline |
| Vadadustat | バフセオ錠150mg | HIF-PHs | Anemia | Mitsubishi Tanabe Pharmaceutical Co. Ltd |
| Opicapone | オンジェンティス錠25mg | COMT | Parkinson’s disease | Ono pharmaceutical |
| Siponimod | メーゼント錠2mgメーゼント錠0.25mg | EDG1S1PR5 | Chronic progressive multiple sclerosis | Novartis |
| Isatuximab | サークリサ点滴静注100mg | CD38 | Multiple myeloma | Sanofi |
| Capmatinib Hydrochloride | タブレクタ錠150mg | c-Met/HGFR | Non-small cell lung cancer | Novartis |
| Tildrakizumab-asmn | イルミア皮下注100mgシリンジ | IL23IL23R | Plaque psoriasis | Sun Pharm |
| Satralizumab | エンスプリング皮下注120mgシリンジ | IL6RAIL6RB | Neuromyelitis optica | Chandai Pharmaceutical Co. Ltd |
| Melatonin | メラトベル顆粒小児用0.2% | Melatonin receptor | Disturbances in initiating and maintaining sleep | Nobel Medical Management Co. Ltd |
| Remdesivir | ベクルリー点滴静注用100mgベクルリー点滴静注液100mg | RNA-directed RNA polymeraseViral proteins | Novel coronavirus pneumonia | Gilead Sciences Inc |
| Upadacitinib | リンヴォック錠7.5mg | JAK1 | Rheumatoid arthritis | Abbvie Gk |
| Lurasidone Hydrochloride | ラツーダ錠60mgラツーダ錠20mgラツーダ錠40mgラツーダ錠80mg | 5-HT1A5-HT2A5-HT7DRD2 | Schizophrenia | Sumitomo Dainippon Pharma Co Ltd |
| Tirabrutinib hydrochloride | ベレキシブル錠80mg | BTK | Lymphoma | Ono pharmaceutical |
| Borofalan (10B) | ステボロニン点滴静注バッグ 9000mg/300mL | Unidentified | Head and neck cancer | Stella Pharma Co |
| Viltolarsen | ビルテプソ点滴静注250mg | DystroglycanDystrophin pre-mRNA | Duchenne muscular dystrophy | Nnippon-shinyaku |
| Cabozantinib S-malate | カボメティクス錠20mgカボメティクス錠60mg | AXLKITNTRK2RETROSTIE2TYRO3VEGFR1VEGFR2VEGFR3c-Met/HGFR | Renal cell carcinoma | Takeda |
| Von Willebrand factor (Recombinant) | ボンベンディ静注用1300 | F8 | Von Willebrand’s disease | Shire Japan Kk |
| Sodium zirconium cyclosilicate | ロケルマ懸濁用散分包5gロケルマ懸濁用散分包10g | Potassium | Hyperkalemia | AstraZeneca |
| Fam-trastuzumab deruxtecan | エンハーツ点滴静注用100mg | HER2TOP1 | Breast cancer | Daiichi Sankyo Co |
| Tepotinib hydrochloride hydrate | テプミトコ錠250mg | c-Met/HGFR | Non-small cell lung cancer | Merck |
| Brolucizumab | ベオビュ硝子体内注射用キット120mg/mL | VEGFA | Age-related macular degeneration | Novartis |
| Delgocitinib | コレクチム軟膏0.5% | JAK | Dermatitis atopic | Japan Tobacco (Hong Kong) Limited |
| Darolutamide | ニュベクオ錠300mg | AR | Castration-resistant prostate cancer | Bayer |
| Remimazolam Besilate | アネレム静注用50mg | GABAAR | Anesthesia Sedation | Mundipharma Kk |
| Dotinurad | ユリス錠0.5mg | URAT1 | Gout Hyperuricemia | Fuji Yakuhin Co Ltd |
| Posaconazole | ノクサフィル錠100mgノクサフィル点滴静注300mg | CYP51A1 | Fungal infection | Merck Sharp & Dohme Bv |
| Lemborexant | デエビゴ錠5mgデエビゴ錠10mg | OX1ROX2R | Disturbances in initiating and maintaining sleep | Eisai Inc |
| Doravirine | ピフェルトロ錠100mg | RT | HIV infection | Merck Sharp & Dohme Bv |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Vortioxetine Hydrobromide | トリンテリックス錠10mgトリンテリックス錠20mg | 5-HT1A5-HT1B5-HT1D5-HT35-HT7SERT | Severe depressive disorder | Takeda |
| Lascufloxacin | ラスビック点滴静注キット150mgラスビック錠75mg | Unidentified | Otodtinolaryngologic diseaseRespiratory tract infection Pulmonitis | Kyorin Holdings Inc |
| Insulin degludec/Liraglutide | ゾルトファイ配合注フレックスタッチ | GLP1RINSR | Type 2 diabetes mellitus | Novo Nordisk |
| Defibrotide sodium | デファイテリオ静注200mg | PAI-1TMvWF | Hepatic vein obstruction disease | Nippon-shinyaku |
| Quizartinib | ヴァンフリタ錠17.7mg | FLT3 | Acute myelocytic leukaemia | Daiichi Sankyo Co |
| Ravulizumab | ユルトミリス点滴静注300mg | C5 | Paroxysmal nocturnal hemoglobinuria | Alexion Pharmaceuticals Inc |
| Necitumumab | ポートラーザ点滴静注液800mg | EGFR | Non-small cell lung cancer | Nippon Kayaku Co Ltd |
| Entrectinib | ロズリートレクカプセル100mgロズリートレクカプセル200mg | ALKNTRK2NTRK3ROSTRKA | Non-small cell lung cancer | Chugai |
| Peficitinib | スマイラフ錠50mgスマイラフ錠100mg | JAK1JAK2JAK3TYK2 | Rheumatoid arthritis | Astellas Pharma Inc |
| Elapegademase-lvlr | レブコビ筋注2.4mg | Adenosine | Adenosine deaminase deficiency | Teijin |
| Ferric Carboxymaltose | フェインジェクト静注500mg | Unidentified | Ferropenic anaemia | Zeria Pharmaceutical |
| Apalutamide | アーリーダ錠60mg | AR | Prostatic cancer | Janssen |
| Risankizumab | スキリージ皮下注75mgシリンジ0.83mL | IL23 | Psoriasis Psoriatic arthropathy | AbbVie |
| Lisdexamfetamine Dimesylate | ビバンセカプセル20mgビバンセカプセル30mg | ADRA1BDAT | Attention deficit disorder with hyperactivity | Shionogi |
| Treprostinil | トレプロスト注射液50mgトレプロスト注射液100mgトレプロスト注射液20mgトレプロスト注射液200mg | PTGIR | Pulmonary arterial hypertension | Mochida |
| Beperminogene perplasmid | HGF | Peripheral arterial disease Ischemia | Anges | |
| Esaxerenone | ミネブロ錠2.5mgミネブロ錠1.25mgミネブロ錠5mg | MR | Hypertension | Daiichi Sankyo |
| Mirogabalin besilate | タリージェ錠5mgタリージェ錠2.5mgタリージェ錠10mg | CACNA2D1 | Postherpetic neuralgia Diabetic neuropathy Peripheral nervous system disorder | Daiichi Sankyo |
| Relugolix | レルミナ錠40mg | GnRHR | Leiomyoma | Aska Pharmaceutical |
| Dacomitinib | ビジンプロ錠45mgビジンプロ錠15mg | EGFRHER2HER4 | Non-small cell lung cancer | Pfizer |
| Nalmefene Hydrochloride | セリンクロ錠10mg | Opioid receptorsmu/kappa/delta | Alcoholism | Otsuka Holdings Co Ltd |
| Romosozumab | イベニティ皮下注105mgシリンジ | SO | Osteoporosis | Amgen |
| Binimetinib | メクトビ錠15mg | MEK1MEK2 | Melanoma | Ono Pharmaceutical |
| Encorafenib | ビラフトビカプセル50mg | B-raf | Melanoma | Ono Pharmaceutical |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Damoctocog alfa pegol | ジビイ静注用3000ジビイ静注用2000ジビイ静注用1000ジビイ静注用500 | F10 | Hemophilia A | Bayer |
| Omidenepag isopropyl | エイベリス点眼液0.002％ | PTGER2 | Glaucoma Ocular hypertension | Santian Pharmaceutical Co., Ltd |
| Anagliptin/Metformin Hydrochloride | メトアナ配合錠HDメトアナ配合錠LD | DPP4PRKAB1 | Type 2 diabetes mellitus | Mitsuwa Chemical Research Institute |
| Lorlatinib | ローブレナ錠100mgローブレナ錠25mg | ALKROS | Non-small cell lung cancer | Pfizer |
| Gilteritinib Fumarate | ゾスパタ錠40mg | AXLFLT3 | Acute myelocytic leukaemia | Astellas Pharma Inc |
| Vibegron | ベオーバ錠50㎎ | ADRB3 | Overactive bladder | Kyorin Pharmaceutical Co Ltd |
| Blinatumomab | ビーリンサイト点滴静注用35μg | CD19CD3 | B-cell lymphoblastic leukemia-lymphoma | Amgen |
| Icatibant Acetate | フィラジル皮下注30mgシリンジ | BKR2 | Precursor B-cell lymphoblastic leukemia-lymphoma | Shire Pharmaceuticals |
| Baloxavir Marboxil | ゾフルーザ錠20mgゾフルーザ顆粒2%分包ゾフルーザ顆粒2％分包ゾフルーザ錠10mg | PA | Influenza A virus infectionInfluenza B virus infection | Shionogi Pharmaceutical Co. Ltd |
| Abemaciclib | ベージニオ錠150mgベージニオ錠50mgベージニオ錠100mg | CDK4CDK6 | Breast cancer | Eli Lilly |
| Nonacog beta pegol | レフィキシア静注用2000レフィキシア静注用1000レフィキシア静注用500 | F10 | Hemophilia B | Novo Nordisk |
| Vedolizumab | エンタイビオ点滴静注用300mg | ITGA4&ITGB7 | Colitis ulcerative Ulcerative Colitis | Takeda |
| Spiramycin | スピラマイシン錠150万単位「サノフィ」 | Unidentified | Toxoplasma infection | Sanofi |
| Fidaxomicin | ダフクリア錠200mg | RNAP | Enteritis Clostridium difficile infection | Astellas Pharma Inc |
| Durvalumab | イミフィンジ点滴静注500mgイミフィンジ点滴静注120mg | PD-L1 | Non-small cell lung cancer | AstraZeneca |
| Obinutuzumab | ガザイバ点滴静注1000mg | CD20 | Follicular center cell lymphoma | Chandai |
| Evocalcet | オルケディア錠1mgオルケディア錠2mg | CaSR | Secondary Hyperparathyroidism | Kyowa Hakko Kirin Co |
| Rasagiline Mesylate | アジレクト錠1mgアジレクト錠0.5mg | MAOB | Parkinson’s disease | Takeda |
| Migalastat Hydrochloride | ガラフォルドカプセル123mg | α-Gal A | Fabry disease | Amicus Therapeutics Inc |
| Emicizumab | ヘムライブラ皮下注60mgヘムライブラ皮下注105mgヘムライブラ皮下注30mgヘムライブラ皮下注90mgヘムライブラ皮下注150mg | F10F9 | Hemophilia A | Chandai |
| Guselkumab | トレムフィア皮下注100mgシリンジ | IL-23p19 | Psoriasis Psoriatic arthropathy | Janssen |
| Semaglutide | GLP1R | Type 2 diabetes mellitus | Novo Nordisk | |
| Letermovir | プレバイミス錠240mgプレバイミス点滴静注240mg | UL30UL54 | Cytomegalovirus infection | Merck |
| Tedizolid Phosphate | シベクトロ点滴静注用200mgシベクトロ錠200mg | 50S ribosomal subunit | Staphylococcal infection | Merck |
| Condoliase (Seikagaku corporation) | ヘルニコア椎間板注用1.25単位 | Chondroitin sulfate proteoglycansGAG | Intervertebral disc displacement | Seikagaku |
| Fosravuconazole L-Lysine Ethanolate | ネイリンカプセル100mg | CYP51 | Nail tinea | Sato pharmaceutical |
| Elobixibat Hydrate | グーフィス錠5mg | IBAT | Constipation | Ea Pharma |
| Inotuzumab Ozogamicin | ベスポンサ点滴静注用1mg | CD22DNA | Acute lymphocytic leukemia | Pfizer |
| Benralizumab | ファセンラ皮下注30mgシリンジ | IL5RA | Asthma | AstraZeneca |
| Dupilumab | デュピクセント皮下注300mgシリンジ | IL4RA | Dermatitis atopic | Sanofi |
| Bedaquiline Fumarate | サチュロ錠100mg | ATP synthase | Pulmonary tuberculosis | Janssen |
| Olaparib | リムパーザ錠100mgリムパーザ錠150mg | PARP-2PARP-3PARP1 | Ovarian cancer | AstraZeneca |
| Atezolizumab | テセントリク点滴静注1200mg | PD-L1 | Non-small cell lung cancer | Chandai |
| Brexpiprazole | レキサルティ錠1mg | 5-HT1A5-HT2ADRD2 | Schizophrenia | Otsuka Holdings Co Ltd |
| Generic_Name | Brand_Name | Drug_Target | Treatment | Company |
|---|---|---|---|---|
| Lonoctocog alfa | エイフスチラ静注用3000エイフスチラ静注用250エイフスチラ静注用1500エイフスチラ静注用2000エイフスチラ静注用2500エイフスチラ静注用500エイフスチラ静注用1000 | F10 | Hemophilia A | American Jetbellin Biological Products Co., Ltd |
| Sarilumab | ケブザラ皮下注200mgシリンジケブザラ皮下注150mgシリンジ | IL6RAIL6RB | Rheumatoid arthritis | Sanofi |
| Avelumab | バベンチオ点滴静注200mg | PD-L1 | Merkel cell carcinoma | Merck Serono |
| Flutemetamol (18F) | ビザミル静注 | APP | Contrast agent | Nihon Medi-Physics |
| Bezlotoxumab | ジーンプラバ点滴静注625mg | BTXtoxB | Diarrhea Clostridium difficile infection | Merck |
| Belimumab | ベンリスタ点滴静注用400mgベンリスタ皮下注200mgオートインジェクターベンリスタ皮下注200mgシリンジベンリスタ点滴静注用120mg | BAFF/BLyS | Systemic lupus erythematosus | GlaxoSmithKline |
| Rupatadine Fumarate | ルパフィン錠10mg | HRH1Platelet-activating factor | Eczema Dermatitis Pruritus UrticariaAllergic rhinitis | Teikoku Pharma Usa |
| Daratumumab | ダラザレックス点滴静注100mgダラザレックス点滴静注400mg | CD38 | Multiple myeloma | Janssen |
| Palbociclib | イブランスカプセル125mgイブランスカプセル25mg | CDK4CDK6 | Breast cancer | Pfizer |
| Amenamevir | アメナリーフ錠200mg | DNA helicase/primase complex | Herpes zoster | Maruho |
| Baricitinib | オルミエント錠2mgオルミエント錠4mg | JAK1JAK2 | Rheumatoid arthritis | Eli lilly |
| Pralatrexate | ジフォルタ注射液20mg | DHFR | Peripheral T-cell lymphoma | Mundipharma Kk |
| Romidepsin | イストダックス点滴静注用10mg | HDAC | Peripheral T-cell lymphoma | Celgene Corp |
| Nusinersen sodium | スピンラザ髄注12mg | SMNSmall interfering RNA | Spinal muscular atrophy | Biogene |
| Pemafibrate | パルモディア錠0.1mg | PPARα | Hyperlipemia | Shinwa Co., Ltd |
| Hydromorphone Hydrochloride | ナルラピド錠1mg | Opioid receptorsmu/kappa/delta | Pain | Daiichi Sankyo Co |
| Ziv-aflibercept | ザルトラップ点滴静注100mgザルトラップ点滴静注200mg | PGFVEGFA | Colorectal carcinoma | Sanofi |
| Forodesine Hydrochloride | ムンデシンカプセル100mg | PNP | Peripheral T-cell lymphoma | Mundipharma Kk |
| Ixazomib Citrate | ニンラーロカプセル4mgニンラーロカプセル2.3mgニンラーロカプセル3mg | Proteasome | Multiple myeloma | Takeda |
| Naldemedine Tosylate | スインプロイク錠0.2mg | MOR1 | Opiates-induced constipation | Shionogi Pharmaceutical Co. Ltd |
| Drug target | Approved | Vet approved | Investigational |
|---|---|---|---|
| VDCCs | 100 | 1 | 31 |
| COXs | 199 | 1 | 24 |
| EGFR | 30 | 2 | 150 |
| DNA | 67 | 2 | 50 |
| HER2 | 30 | 7 | 159 |
| PD-L1 | 5 | 3 | 124 |
| CD3 | 6 | 1 | 134 |
| Tubulin | 25 | 1 | 73 |
| F10 | 102 | 8 | 38 |
| CD19 | 9 | 0 | 214 |
| GR | 140 | 3 | 36 |
| GABAAR | 90 | 2 | 28 |
| ERs | 74 | 1 | 33 |
| HRH1 | 153 | 0 | 18 |
| INSR | 82 | 10 | 68 |
| PBPs | 139 | 0 | 21 |
| PD-1 | 15 | 2 | 108 |
| DRD2 | 62 | 0 | 29 |
| TNFα | 58 | 5 | 46 |
| GLP1R | 11 | 4 | 84 |
| Brand Name | GenericName | Company | Sales in 2021(in $ billion) |
|---|---|---|---|
| Comirnaty | COVID-19 Vaccine, mRNA | Pfizer, BioNTech | 36.8 |
| Humira | Adalimumab | AbbVie | 20.7 |
| Spikevax | COVID-19 Vaccine, mRNA | Moderna | 17.7 |
| Keytruda | Pembrolizumab | Merck & Co. | 17.2 |
| Eliquis | Apixaban | Bristol Myers Squibb, Pfizer | 16.73 |
| Revlimid | Lenalidomide | Bristol Myers Squibb | 12.8 |
| Imbruvica | Ibrutinib | AbbVie, Johnson & Johnson | 9.8 |
| Stelara | Ustekinumab | Johnson & Johnson | 9.1 |
| Eylea | Afibercept | Regeneron Pharmaceuticals, Bayer | 8.9 |
| Biktarvy | Bictegravir/Emtricitabine/Tenofovir alafenamide | Gilead Sciences | 8.6 |
| Opdivo | Nivolumab | Bristol Myers Squibb, Ono Pharmaceutical | 8.5 |
| Xarelto | Rivaroxaban | Bayer, Johnson & Johnson | 7.5 |
| REGEN-COV/Ronapreve | Casirivimab and Imdevimab | Regeneron, Roche | 7.5 |
| Trulicity | Dulaglutide | Eli Lilly | 6.5 |
| Darzalex | Daratumumab | Johnson & Johnson | 6 |
| Trikafta/Kaftrio | Ivacaftor/Tezacaftor/Elexacaftor | Vertex Pharmaceuticals | 5.7 |
| Gardasil 9 | Elexacaftor/Tezacaftor/Ivacaftor | Merck | 5.7 |
| Dupixent | Dupilumab | Sanofi, Regeneron Pharmaceuticals | 5.6 |
| Veklury | Remdesivir | Gilead Sciences | 5.6 |
| Ibrance | Palbocilib | Pfizer | 5.4 |
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