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Denifanstat

Sagimet Biosciences announced positive topline results from its FASCINATE-2 Phase 2b clinical trial of denifanstat versus placebo in biopsy-confirmed non-alcoholic steatohepatitis (NASH) patients with stage 2 or stage 3 fibrosis (F2/F3) at week 52. Denifanstat, an oral, selective FASN inhibitor, achieved statistically significant results on primary and multiple secondary endpoints.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.

tert-butyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate
tert-butyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate
CM127634
163209-96-9
tert-butyl 4-(4-cyanophenyl)-3,6-dihydro-2H-pyridine-1-carboxylate
tert-butyl 4-(4-cyanophenyl)-3,6-dihydro-2H-pyridine-1-carboxylate
CM1075240
460365-08-6
tert-Butyl 4-(4-cyanophenyl)piperidine-1-carboxylate
tert-Butyl 4-(4-cyanophenyl)piperidine-1-carboxylate
CM127694
162997-33-3
4-(Piperidin-4-yl)benzonitrile hydrochloride
4-(Piperidin-4-yl)benzonitrile hydrochloride
CM160042
162997-34-4
4-cyclobutyl-2-methyl-5-(5-methyl-4H-1,2,4-triazol-3-yl)benzoicacid
4-cyclobutyl-2-methyl-5-(5-methyl-4H-1,2,4-triazol-3-yl)benzoicacid
CM1075241
1399181-93-1