製品名:3-((Benzyloxy)methyl)oxetane

IUPAC Name:3-[(benzyloxy)methyl]oxetane

CAS番号:1003013-76-0
分子式:C11H14O2
純度:95%
カタログ番号:CM247251
分子量:178.23

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製品詳細

CAS番号:1003013-76-0
分子式:C11H14O2
融点:-
SMILESコード:C1(COCC2=CC=CC=C2)COC1
密度:
カタログ番号:CM247251
分子量:178.23
沸点:
MDL番号:MFCD20482348
保管方法:Keep in inert atmosphere, store at 2-8°C.

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

Column Infos

Benzenes
Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.