製品名:PPC-NHS ester

IUPAC Name:2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate

CAS番号:107348-47-0
分子式:C13H14N2O4S2
純度:95%+
カタログ番号:CM338847
分子量:326.39

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CM338847-100mg 1-2 Weeks ƩǕǺ
CM338847-1g 3-4 Weeks ƻƏƻƩ

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製品詳細

CAS番号:107348-47-0
分子式:C13H14N2O4S2
融点:-
SMILESコード:CC(SSC1=NC=CC=C1)CC(ON2C(CCC2=O)=O)=O
密度:
カタログ番号:CM338847
分子量:326.39
沸点:
MDL番号:
保管方法:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Disulfides/Thiols
In chemistry, a disulfide is a compound containing a R−S−S−R′ functional group or the S 2− anion. Thiols are the sulfur analogue of alcohols.

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