製品名:methyl 5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxylate

IUPAC Name:methyl 5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxylate

CAS番号:1103500-32-8
分子式:C15H12F3NO4
純度:95%
カタログ番号:CM327352
分子量:327.26

包装単位 有効在庫 価格(USD) 数量
CM327352-100mg 3-4 Weeks țȬȬ
CM327352-250mg 3-4 Weeks Ȭǧƀ
CM327352-1g 4-5 Weeks ɅŴNJ
CM327352-5g 6-7 Weeks țțŴƙ

研究開発用専用.

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製品詳細

CAS番号:1103500-32-8
分子式:C15H12F3NO4
融点:-
SMILESコード:O=C(C1=C(C2CC2)ON=C1C3=CC=CC=C3OC(F)(F)F)OC
密度:
カタログ番号:CM327352
分子量:327.26
沸点:
MDL番号:
保管方法:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
Isoxazoles
Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.

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