製品名:6-chloro-3-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazine

IUPAC Name:6-chloro-3-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazine

CAS番号:1152552-07-2
分子式:C8H7ClN4
純度:95%
カタログ番号:CM122081
分子量:194.62

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CM122081-100mg in stock ţƴǎ
CM122081-250mg in stock řǎŁ
CM122081-1g in stock ǟƴij

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製品詳細

CAS番号:1152552-07-2
分子式:C8H7ClN4
融点:-
SMILESコード:ClC1=NN2C(C=C1)=NN=C2C3CC3
密度:
カタログ番号:CM122081
分子量:194.62
沸点:
MDL番号:MFCD11103598
保管方法:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.