製品名:4-Cyclopropyl-3,4-dihydroquinoxalin-2(1H)-one

IUPAC Name:4-cyclopropyl-1,2,3,4-tetrahydroquinoxalin-2-one

CAS番号:115618-81-0
分子式:C11H12N2O
純度:95%+
カタログ番号:CM221539
分子量:188.23

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製品詳細

CAS番号:115618-81-0
分子式:C11H12N2O
融点:-
SMILESコード:O=C1NC2=C(C=CC=C2)N(C3CC3)C1
密度:
カタログ番号:CM221539
分子量:188.23
沸点:
MDL番号:
保管方法:

Category Infos

Quinoxalines
Quinoxalines, also known as benzopyrazines, are heterocyclic compounds containing a ring complex consisting of a benzene ring and a pyrazine ring. It has isomerism with other naphthalene compounds such as quinazoline, phthalazine, cinnamine, etc. Fusion N-heterocyclic compounds are widely used as valuable entities for the expansion of important pharmacological agents and are considered to be an advantageous scaffold material. Among the numerous fused N-heterocyclic compounds, cinnoline, quinoxaline and quinazoline are important pharmacological agents. In medicinal chemistry, these N-heterocyclic compounds have a wide range of biological properties and can be used as synthetic intermediates, potential drug candidates and chemical probes.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos