製品名:2-Chloro-5-(difluoromethoxy)pyrimidine

IUPAC Name:2-chloro-5-(difluoromethoxy)pyrimidine

CAS番号:1192813-64-1
分子式:C5H3ClF2N2O
純度:95%+
カタログ番号:CM325391
分子量:180.54

包装単位 有効在庫 価格(USD) 数量
CM325391-1g in stock ȃůǤ
CM325391-5g in stock ƓIJǤ
CM325391-10g in stock ȃIJŹIJ

研究開発用専用.

問い合わせフォーム

   refresh    

製品詳細

CAS番号:1192813-64-1
分子式:C5H3ClF2N2O
融点:-
SMILESコード:FC(F)OC1=CN=C(Cl)N=C1
密度:
カタログ番号:CM325391
分子量:180.54
沸点:260.1±30.0°C at 760 mmHg
MDL番号:MFCD18415615
保管方法:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

AZD0780
AstraZeneca announced Phase I trial data for its PCSK9 inhibitor, AZD0780. AZD0780 is an oral small molecule PCSK9 inhibitor as a first-in-class therapy for patients with dyslipidemia that cannot be controlled by statins alone. PSCK9 is a well-known and validated target in lipid metabolism and inhibiting PSCK9 signalling has shown to be effective in reducing LDL cholesterol levels in plasma. Lower LDL-C levels are associated with a reduction in the risk of long-term cardiovascular disease and major cardiovascular events.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.