製品名:3-Chloropyrazine-2-carbaldehyde

IUPAC Name:3-chloropyrazine-2-carbaldehyde

CAS番号:121246-96-6
分子式:C5H3ClN2O
純度:95%+
カタログ番号:CM168507
分子量:142.54

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製品詳細

CAS番号:121246-96-6
分子式:C5H3ClN2O
融点:-
SMILESコード:O=CC1=NC=CN=C1Cl
密度:
カタログ番号:CM168507
分子量:142.54
沸点:214.3°C at 760 mmHg
MDL番号:MFCD07371660
保管方法:Store at 2-8°C.

Category Infos

Pyrazines
Pyrazine is a heterocyclic aromatic organic compound with chemical formula C4H4N2. The marketed pyrazine drugs are mainly distributed in the field of anti-tumor and anti-infection. In recent years, there have been many new drugs in various fields, and there are some new target drugs worthy of attention.
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Column Infos

Acalabrutinib
In positive interim analysis results from the phase 3 trial ECHO, acalabrutinib (Calquence; AstraZeneca) in combination with standard of care chemoimmunotherapy—bendamustine and rituximab—demonstrated both statistically significant and clinically meaningful improvement in progression-free survival (PFS) in adult patients with previously untreated mantle cell lymphoma (MCL) compared with standard of care alone. Acalabrutinib is a next-generation, selective inhibitor of Bruton tyrosine kinase (BTK) that binds covalently to BTK to hinder its activity. BTK signaling results in the activation of pathways that are necessary for B-cell proliferation, trafficking, chemotaxis, an adhesion within B cells.