製品名:2-(chloromethyl)-6-(trifluoromethyl)pyrimidin-4-ol

IUPAC Name:2-(chloromethyl)-6-(trifluoromethyl)pyrimidin-4-ol

CAS番号:1240596-45-5
分子式:C6H4ClF3N2O
純度:95%+
カタログ番号:CM388537
分子量:212.56

包装単位 有効在庫 価格(USD) 数量
CM388537-500mg in stock ħijŤ
CM388537-1g in stock ǸƴŮ
CM388537-5g 1-2 Weeks ǟǸŤƴ
CM388537-10g 3-4 Weeks ijƴƚƴ

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製品詳細

CAS番号:1240596-45-5
分子式:C6H4ClF3N2O
融点:-
SMILESコード:OC1=CC(=NC(CCl)=N1)C(F)(F)F
密度:
カタログ番号:CM388537
分子量:212.56
沸点:
MDL番号:
保管方法:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.

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