製品名:3-(4-(Tributylstannyl)thiazol-2-yl)oxetan-3-ol

IUPAC Name:3-[4-(tributylstannyl)-1,3-thiazol-2-yl]oxetan-3-ol

CAS番号:1245816-13-0
分子式:C18H33NO2SSn
純度:95%
カタログ番号:CM284084
分子量:446.24

包装単位 有効在庫 価格(USD) 数量
CM284084-250mg in stock ŴɅȁ
CM284084-500mg in stock Ʌȁȷ
CM284084-1g in stock ǧƻɅ

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製品詳細

CAS番号:1245816-13-0
分子式:C18H33NO2SSn
融点:-
SMILESコード:OC1(C2=NC([Sn](CCCC)(CCCC)CCCC)=CS2)COC1
密度:
カタログ番号:CM284084
分子量:446.24
沸点:
MDL番号:MFCD16140389
保管方法:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.