製品名:1-(oxetan-3-yl)piperazine

IUPAC Name:1-(oxetan-3-yl)piperazine

CAS番号:1254115-23-5
分子式:C7H14N2O
純度:95%+
カタログ番号:CM104047
分子量:142.2

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製品詳細

CAS番号:1254115-23-5
分子式:C7H14N2O
融点:-
SMILESコード:C1OCC1N1CCNCC1
密度:
カタログ番号:CM104047
分子量:142.2
沸点:
MDL番号:MFCD21847918
保管方法:

Category Infos

Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

Column Infos