製品名:2-amino-2-(oxetan-3-yl)acetic acid

IUPAC Name:2-amino-2-(oxetan-3-yl)acetic acid

CAS番号:1270019-87-8
分子式:C5H9NO3
純度:95%+
カタログ番号:CM106358
分子量:131.13

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製品詳細

CAS番号:1270019-87-8
分子式:C5H9NO3
融点:-
SMILESコード:O=C(O)C(N)C1COC1
密度:
カタログ番号:CM106358
分子量:131.13
沸点:
MDL番号:MFCD17392891
保管方法:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

Column Infos

Amino Acids and Peptides
Amino acids are organic compounds containing a basic amino group and an acidic carboxyl group. Because amino acids contain both amino and carboxyl groups, they can be polymerized in an end-to-end manner, removing a molecule of water to form a covalent amide bond or peptide bond. Many amino acids are linked together end to end to form a polypeptide. Amino acids and peptides are important components in the fields of medicine and life sciences.