製品名:9-Bromo-5,6-dihydro-2-iodo-imidazo[1,2-d][1,4]benzoxazepine

IUPAC Name:12-bromo-4-iodo-9-oxa-3,6-diazatricyclo[8.4.0.0²,⁶]tetradeca-1(14),2,4,10,12-pentaene

CAS番号:1282516-69-1
分子式:C11H8BrIN2O
純度:95%+
カタログ番号:CM152652
分子量:391.01

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製品詳細

CAS番号:1282516-69-1
分子式:C11H8BrIN2O
融点:-
SMILESコード:IC1=CN2CCOC3=CC(Br)=CC=C3C2=N1
密度:
カタログ番号:CM152652
分子量:391.01
沸点:
MDL番号:MFCD22690733
保管方法:2-8°C

Category Infos

Imidazoles
Imidazole is an important five-membered nitrogen-containing heterocyclic compound. Among the numerous heterocyclic compounds, imidazole and its derivatives are regarded as a unique and multifaceted scaffold material due to their diverse applications in industrial, organic and pharmaceutical chemistry. Imidazoles interact in different ways with many therapeutic targets, enzymes and receptors in biological systems and thus exhibit a wide range of biological activities. In particular, several imidazoles can be used as clinical drugs to treat various types of cancer with high therapeutic efficacy. Furthermore, imidazoles are one of the most critical segments in the field of anti-covid-19 virus drug discovery due to their ability to interact with active targets in living systems.
Imidazole Manufacturer
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Column Infos

Inavolisib
Genentech’s Phase III results show that the Inavolisib (GDC-0077) treatment meets the primary end point in hormone receptor (HR)-positive, HER2-negative, PIK3CA-mutated Breast Cancer. The combination of Inavolisib with Palbociclib and fulvestrant improves the progression-free survival (PFS) in the first line. Inavolisib is a potent selective inhibitor of PI3K alpha (PI3Kα) that binds to the ATP-binding site of p110α, and promotes the degradation of mutated p110α.