Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Imidazolidine is a heterocyclic compound (CH2)2(NH)2CH2. The parental imidazolidines are less studied, but related compounds substituted on one or both nitrogen centers are more common. Generally, they are colorless, polar, basic compounds. Imidazolidines are examples of cyclic 5-membered general amines. Imidazolidine derivatives are key components in the development of bioactive compounds for the treatment of various diseases, especially Chagas disease. In fact, other studies have shown that imidazoline-2,4-diones have a wide range of pharmacological activities, including anticonvulsant, antiarrhythmic, and antiparasitic.
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