製品名:2-(2-oxaspiro[3.3]heptan-6-ylidene)acetonitrile

IUPAC Name:2-{2-oxaspiro[3.3]heptan-6-ylidene}acetonitrile

CAS番号:1339892-67-9
分子式:C8H9NO
純度:95%+
カタログ番号:CM1018229
分子量:135.17

包装単位 有効在庫 価格(USD) 数量
CM1018229-250mg in stock ɅƀNJ
CM1018229-500mg in stock ƦƦțŴ
CM1018229-1g in stock ƦȬNJNJ

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製品詳細

CAS番号:1339892-67-9
分子式:C8H9NO
融点:-
SMILESコード:N#CC=C1CC2(COC2)C1
密度:
カタログ番号:CM1018229
分子量:135.17
沸点:
MDL番号:
保管方法:

Category Infos

Cyclobutanes
The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.
Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.