cas 134099-33-5|| where to buy 2,5-difluoro-4-(trifluoromethyl)benzaldehyde

製品名:2,5-difluoro-4-(trifluoromethyl)benzaldehyde

IUPAC Name:2,5-difluoro-4-(trifluoromethyl)benzaldehyde

: CAS番号：134099-33-5; 分子式：C8H3F5O; 純度：95%+

: カタログ番号：CM458962; 分子量：210.1

包装単位	有効在庫	価格（USD）
CM458962-250mg	3-4 Weeks	ɅƙǕ
CM458962-500mg	4-5 Weeks	ƻȁǧ
CM458962-1g	4-5 Weeks	Ǖȁȁ

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製品詳細

: CAS番号:134099-33-5; 分子式:C8H3F5O; 融点:-; SMILESコード:FC1=CC(C=O)=C(F)C=C1C(F)(F)F; 密度:

: カタログ番号:CM458962; 分子量:210.1; 沸点:; MDL番号:MFCD28714769; 保管方法:

Column Infos

: Nelutroctiv; The Journal of Medicinal Chemistry recently publishes an article titled, “Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility”. Heart failure (HF) is a lifelong clinical syndrome and remains a major societal concern. Cardiac myosin activators constitute a new class of inotropes and are found to be a viable therapeutic approach for increasing myocardial contractility.
CK-136 is a small molecule cardiac troponin activator that is discovered under a previous joint research program between Cytokinetics and Amgen. It acts on the sarcomere and is designed to improve myocardial contractility by sensitizing cardiac troponin to calcium, increasing actin-myosin cross bridge formation during each cardiac cycle. CK-136 is developed as a potential treatment for heart failure (HF) with reduced ejection fraction (HFrEF) and other types of heart failure, and currently under phase 1 clinical investigation.

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