製品名:5-Azetidin-3-yl-3-cyclopropyl-1,2,4-oxadiazole hydrochloride

IUPAC Name:5-(azetidin-3-yl)-3-cyclopropyl-1,2,4-oxadiazole hydrochloride

CAS番号:1351591-40-6
分子式:C8H12ClN3O
純度:97%
カタログ番号:CM561941
分子量:201.65

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CM561941-100mg in stock ŤǙŮ
CM561941-250mg in stock ƈǪŤ
CM561941-1g in stock ȃľŌ

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製品詳細

CAS番号:1351591-40-6
分子式:C8H12ClN3O
融点:-
SMILESコード:C1(C2CC2)=NOC(C3CNC3)=N1.Cl
密度:
カタログ番号:CM561941
分子量:201.65
沸点:
MDL番号:
保管方法:

Category Infos

Oxadiazoles
Oxadiazoles are a class of heterocyclic aromatic compounds with the molecular formula C2H2N2O, which have special biological activities and thermodynamic properties. Five-membered heterocyclic moieties composed of three or two heteroatoms are of great interest to researchers because these compounds show significant therapeutic potential. These heterocycles can serve as a building block for the development of novel molecular structures.
Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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