製品名:1-(Oxetan-3-yl)piperidin-4-amine dihydrochloride

IUPAC Name:1-(oxetan-3-yl)piperidin-4-amine dihydrochloride

CAS番号:1363405-09-7
分子式:C8H18Cl2N2O
純度:95%
カタログ番号:CM181458
分子量:229.15

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製品詳細

CAS番号:1363405-09-7
分子式:C8H18Cl2N2O
融点:-
SMILESコード:NC1CCN(C2COC2)CC1.[H]Cl.[H]Cl
密度:
カタログ番号:CM181458
分子量:229.15
沸点:
MDL番号:
保管方法:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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