製品名:1-(2-hydroxyphenyl)hexahydropyrimidine-2,4-dione

IUPAC Name:1-(2-hydroxyphenyl)-1,3-diazinane-2,4-dione

CAS番号:136582-04-2
分子式:C10H10N2O3
純度:95%
カタログ番号:CM1077448
分子量:206.2

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製品詳細

CAS番号:136582-04-2
分子式:C10H10N2O3
融点:-
SMILESコード:OC1=C(C=CC=C1)N1CCC(=O)NC1=O
密度:
カタログ番号:CM1077448
分子量:206.2
沸点:
MDL番号:
保管方法:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.