製品名:(3R)-3-fluoropyrrolidine hydrochloride

IUPAC Name:(3R)-3-fluoropyrrolidine hydrochloride

CAS番号:136725-55-8
分子式:C4H9ClFN
純度:98%
カタログ番号:CM106718
分子量:125.57

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製品詳細

CAS番号:136725-55-8
分子式:C4H9ClFN
融点:-
SMILESコード:F[C@H]1CNCC1.[H]Cl
密度:
カタログ番号:CM106718
分子量:125.57
沸点:
MDL番号:MFCD04038717
保管方法:

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

Column Infos

Pyrroles
Pyrrole is a five membered heterocyclic compound with the molecular formula of C4H5N. Pyrrole has a ring composed of four carbon atoms and one nitrogen atom. Pyrrole is easy to polymerize in the air. Pyrrole is the parent compound of many important biological substances (such as bile pigment, porphyrin and chlorophyll). Pyrrole scaffolds are widely used in biological and pharmaceutical fields. Pyrrole is a special heterocyclic scaffold, which exists in many natural products, drug molecules and pesticides, and has shown its application in materials science.
Plixorafenib
FORE Biotherapeutics’s Plixorafenib (PLX-8394) is a next-generation, orally selective inhibitor and specific dimer breaker of BRAF protein under clinical development. Its favorable efficacy and tolerability are updated in the recently presented phase 1/2a results in BRAF V600 advanced solid tumors. Plixorafenib was designed to target a wide range of BRAF mutations while sparing wild type forms of RAF. It has been granted Fast Track Designation and Orphan Drug Designation from the U.S. FDA.