製品名:(S)-N-(5-(5-Methoxypyrazin-2-yl)chroman-3-yl)-6-((2,2,2-trifluoroethoxy)methyl)nicotinamide

IUPAC Name:N-[(3S)-5-(5-methoxypyrazin-2-yl)-3,4-dihydro-2H-1-benzopyran-3-yl]-6-[(2,2,2-trifluoroethoxy)methyl]pyridine-3-carboxamide

CAS番号:1369501-46-1
分子式:C23H21F3N4O4
純度:95%
カタログ番号:CM285334
分子量:474.44

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製品詳細

CAS番号:1369501-46-1
分子式:C23H21F3N4O4
融点:-
SMILESコード:O=C(N[C@@H]1COC2=C(C(C3=NC=C(OC)N=C3)=CC=C2)C1)C4=CN=C(COCC(F)(F)F)C=C4
密度:
カタログ番号:CM285334
分子量:474.44
沸点:
MDL番号:
保管方法:

Category Infos

Pyridines
Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
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Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
Pyrazines
Pyrazine is a heterocyclic aromatic organic compound with chemical formula C4H4N2. The marketed pyrazine drugs are mainly distributed in the field of anti-tumor and anti-infection. In recent years, there have been many new drugs in various fields, and there are some new target drugs worthy of attention.
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Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.

Column Infos

Fluorinated compounds
Fluorinated compounds refers to organic or inorganic compounds containing fluorine.