製品名:N-(Cyclopropylsulfonyl)-4,4-dimethyl-2-(3-morpholinophenyl)-1,2,3,4-tetrahydroquinoline-6-carboxamide

IUPAC Name:N-(cyclopropanesulfonyl)-4,4-dimethyl-2-[3-(morpholin-4-yl)phenyl]-1,2,3,4-tetrahydroquinoline-6-carboxamide

CAS番号:1391608-77-7
分子式:C25H31N3O4S
純度:97%
カタログ番号:CM227312
分子量:469.6

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製品詳細

CAS番号:1391608-77-7
分子式:C25H31N3O4S
融点:-
SMILESコード:O=C(C1=CC2=C(NC(C3=CC=CC(N4CCOCC4)=C3)CC2(C)C)C=C1)NS(=O)(C5CC5)=O
密度:
カタログ番号:CM227312
分子量:469.6
沸点:
MDL番号:MFCD30471674
保管方法:

Category Infos

Morpholines
Morpholine contains secondary amine groups and has all the typical reactive characteristics of secondary amine groups. It can react with inorganic acids to form salts, and react with organic acids to form salts or amides, which can be subjected to alkylation reaction, and can also be reacted with ethylene oxide, ketone or Willgerodt reaction. Morpholine is a six-membered ring containing oxygen and nitrogen, and its alkalinity is much lower than that of its parent piperidine. The marketed morpholine drugs are mainly distributed in the fields of tumors, cardiovascular and cerebrovascular diseases, respiratory system diseases, digestive system diseases, infectious diseases and mental disorders.
morpholine price
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
Tetrahydroquinolines
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, widely found in nature and in a variety of pharmacologically active compounds. Tetrahydroquinoline is an important structure for the synthesis of various biologically active derivatives.