製品名:4-cyclopropylthiazole-2-carbohydrazide

IUPAC Name:4-cyclopropyl-1,3-thiazole-2-carbohydrazide

CAS番号:1396762-43-8
分子式:C7H9N3OS
純度:95%
カタログ番号:CM110741
分子量:183.23

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製品詳細

CAS番号:1396762-43-8
分子式:C7H9N3OS
融点:-
SMILESコード:O=C(C1=NC(C2CC2)=CS1)NN
密度:
カタログ番号:CM110741
分子量:183.23
沸点:
MDL番号:
保管方法:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos