製品名:1,2,3,4-Tetrahydro-1,5-naphthyridine

IUPAC Name:1,2,3,4-tetrahydro-1,5-naphthyridine

CAS番号:13993-61-8
分子式:C8H10N2
純度:97%
カタログ番号:CM121909
分子量:134.18

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製品詳細

CAS番号:13993-61-8
分子式:C8H10N2
融点:-
SMILESコード:C12=NC=CC=C1NCCC2
密度:
カタログ番号:CM121909
分子量:134.18
沸点:
MDL番号:MFCD08444439
保管方法:

Category Infos

Naphthyridines
Naphthyridine is a class of aromatic heterocyclic compounds whose chemical formula is C8H6N2. They consist of naphthalene bicyclic rings in which two carbon atoms are replaced by nitrogen atoms. There are ten isomers of naphthyridine, because naphthyridine has two benzene rings, has strong π-π conjugation, and has better luminescence properties. Common naphthyridines are 1,8-naphthyridines. There are many kinds of 1,8-naphthyridine derivatives, and they are widely used.

Column Infos

GDC-1971
Protein tyrosine phosphatase SHP2 mediates RAS-driven MAPK signaling and has emerged in recent years as a target of interest in oncology, both for treating with a single agent and in combination with a KRAS inhibitor. GDC-1971 (formerly RLY-1971) is a SHP2 inhibitor currently in clinical trials in combination with KRAS G12C inhibitor divarasib (GDC-6036) for the treatment of solid tumors driven by a KRAS G12C mutation.