製品名:(2-(Azetidin-1-yl)pyrimidin-5-yl)boronic acid

IUPAC Name:[2-(azetidin-1-yl)pyrimidin-5-yl]boronic acid

CAS番号:1411643-59-8
分子式:C7H10BN3O2
純度:95%+
カタログ番号:CM135138
分子量:178.98

包装単位 有効在庫 価格(USD) 数量
CM135138-250mg in stock ȡȡ
CM135138-1g in stock ƥȡƛ
CM135138-5g in stock ȡȐȐ

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製品詳細

CAS番号:1411643-59-8
分子式:C7H10BN3O2
融点:-
SMILESコード:OB(C1=CN=C(N2CCC2)N=C1)O
密度:
カタログ番号:CM135138
分子量:178.98
沸点:
MDL番号:MFCD18261197
保管方法:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Column Infos

Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).