製品名:(3R)-3-Fluoropyrrolidine-1-sulfonylchloride

IUPAC Name:(3R)-3-fluoropyrrolidine-1-sulfonyl chloride

CAS番号:1411774-27-0
分子式:C4H7ClFNO2S
純度:95%+
カタログ番号:CM419801
分子量:187.61

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製品詳細

CAS番号:1411774-27-0
分子式:C4H7ClFNO2S
融点:-
SMILESコード:F[C@@H]1CCN(C1)S(Cl)(=O)=O
密度:
カタログ番号:CM419801
分子量:187.61
沸点:
MDL番号:
保管方法:

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

Column Infos

Plixorafenib
FORE Biotherapeutics’s Plixorafenib (PLX-8394) is a next-generation, orally selective inhibitor and specific dimer breaker of BRAF protein under clinical development. Its favorable efficacy and tolerability are updated in the recently presented phase 1/2a results in BRAF V600 advanced solid tumors. Plixorafenib was designed to target a wide range of BRAF mutations while sparing wild type forms of RAF. It has been granted Fast Track Designation and Orphan Drug Designation from the U.S. FDA.