製品名:tert-butyl octahydropyrrolo[3,4-c]pyrrole-2-carboxylate

IUPAC Name:tert-butyl octahydropyrrolo[3,4-c]pyrrole-2-carboxylate

CAS番号:141449-85-6
分子式:C11H20N2O2
純度:97%
カタログ番号:CM106941
分子量:212.29

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製品詳細

CAS番号:141449-85-6
分子式:C11H20N2O2
融点:-
SMILESコード:O=C(N1CC(CNC2)C2C1)OC(C)(C)C
密度:
カタログ番号:CM106941
分子量:212.29
沸点:293°C at 760 mmHg
MDL番号:MFCD04115128
保管方法:Keep in dark place, inert atmosphere, store at 2-8°C.

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

Column Infos

Alicyclic Heterocycles
When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound.
Seltorexant
Johnson & Johnson pivotal study of Seltorexant shows statistically significant and clinically meaningful improvement in depressive symptoms and sleep disturbance outcomes. Seltorexant meets all primary and secondary endpoints in the pivotal Phase 3 MDD3001 clinical trial of adult and elderly patients with major depressive disorder (MDD) with insomnia symptoms.
Orexin signaling pathways are found to be associated with depression and anxiety. Orexin neurons receive and transmit signals throughout the central nervous system (CNS) that are modulated by their specific receptors (OX1R, OX2R). Seltorexant is an investigational first-in-class selective antagonist of ORX2 receptor. It is developed as an adjunctive therapy for MDD and for the treatment of insomnia disorder.

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