製品名:sodium 1,1'-((3,3'-disulfanediylbis(propanoyl))bis(oxy))bis(2,5-dioxopyrrolidine-3-sulfonate)

IUPAC Name:2,5-dioxo-3-[(sodiooxy)sulfonyl]pyrrolidin-1-yl 3-{[3-({2,5-dioxo-3-[(sodiooxy)sulfonyl]pyrrolidin-1-yl}oxy)-3-oxopropyl]disulfanyl}propanoate

CAS番号:142702-31-6
分子式:C14H14N2Na2O14S4
純度:95%+
カタログ番号:CM534370
分子量:608.49

包装単位 有効在庫 価格(USD) 数量
CM534370-1g 1-2 Weeks ƻƅƩȋ

研究開発用専用.

問い合わせフォーム

   refresh    

製品詳細

CAS番号:142702-31-6
分子式:C14H14N2Na2O14S4
融点:-
SMILESコード:O=C(CCSSCCC(ON1C(CC(S(=O)(O[Na])=O)C1=O)=O)=O)ON2C(CC(S(=O)(O[Na])=O)C2=O)=O
密度:
カタログ番号:CM534370
分子量:608.49
沸点:
MDL番号:
保管方法:

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Disulfides/Thiols
In chemistry, a disulfide is a compound containing a R−S−S−R′ functional group or the S 2− anion. Thiols are the sulfur analogue of alcohols.