Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.
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Among the heterocyclic compounds, pyridopyrazine compounds are widely used as intermediates in the preparation of advanced pharmaceutical materials with biological activity, and are the scaffolding materials that have been widely concerned by academia and industry in recent years. There are many pyridopyrazine derivatives on the market for the treatment of various pharmacological diseases.