Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Dioxane, an organic compound, also known as dioxane, 1,4-dioxane, is an organic substance, the molecular formula is C4H8O2. It is a colorless and transparent liquid, slightly fragrant, miscible with water, miscible most organic solvents. The compound is used in the manufacture of special fine chemicals such as medicine, cosmetics, and fragrance, as well as as a solvent, reaction medium, and extraction agent in scientific research.
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