製品名:2-Chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one

IUPAC Name:2-chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS番号:1449598-86-0
分子式:C8H4ClFN2O
純度:95%+
カタログ番号:CM337294
分子量:198.58

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製品詳細

CAS番号:1449598-86-0
分子式:C8H4ClFN2O
融点:-
SMILESコード:O=C1C=C(Cl)N=C2N1C=C(F)C=C2
密度:
カタログ番号:CM337294
分子量:198.58
沸点:
MDL番号:MFCD28659052
保管方法:

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Risdiplam
As the first approved small molecule splicing modifier drug, Risdiplam (Evrysdi) is granted approval by the European Commission to expand the EU marketing authorization. This extension now includes infants with a clinical diagnosis of SMA Type 1, Type 2 or Type 3 or with one to four SMN2 copies from birth to below two months. Type 1 spinal muscular atrophy (SMA) is a rare, progressive neuromuscular disease and a leading genetic factor of infant mortality, that is caused by low levels of functional survival of motor neuron (SMN) protein. Risdiplam modifies SMN2 pre-messenger RNA splicing and increases levels of functional SMN protein in both the central nervous system and peripheral organs.