製品名:Oxetan-3-yl methanesulfonate

IUPAC Name:oxetan-3-yl methanesulfonate

CAS番号:148430-81-3
分子式:C4H8O4S
純度:95%
カタログ番号:CM200585
分子量:152.16

包装単位 有効在庫 価格(USD) 数量
CM200585-250mg in stock NJǤ
CM200585-1g in stock ŹǵŹ
CM200585-5g in stock ǤǤĽ

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製品詳細

CAS番号:148430-81-3
分子式:C4H8O4S
融点:-
SMILESコード:CS(=O)(OC1COC1)=O
密度:
カタログ番号:CM200585
分子量:152.16
沸点:308.9±31.0°C at 760 mmHg
MDL番号:MFCD18207677
保管方法:Keep in inert atmosphere, store at 2-8°C.

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.