製品名:5-chloro-3-(cyclopropylmethyl)-1,2,4-thiadiazole

IUPAC Name:5-chloro-3-(cyclopropylmethyl)-1,2,4-thiadiazole

CAS番号:1503960-11-9
分子式:C6H7ClN2S
純度:95%+
カタログ番号:CM464005
分子量:174.65

包装単位 有効在庫 価格(USD) 数量
CM464005-250mg 3-4 Weeks ƞȀƞ
CM464005-500mg 4-5 Weeks Ŕǯň
CM464005-1g 4-5 Weeks ňźź

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製品詳細

CAS番号:1503960-11-9
分子式:C6H7ClN2S
融点:-
SMILESコード:ClC1=NC(CC2CC2)=NS1
密度:
カタログ番号:CM464005
分子量:174.65
沸点:
MDL番号:MFCD23913445
保管方法:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
Thiadiazoles
Thiadiazoles are a subfamily of azoles. Structurally, they are five-membered heterocyclic compounds containing two nitrogen atoms and one sulfur atom, and two double bonds, forming an aromatic ring. Depending on the relative positions of the heteroatoms, there are four possible structures; these forms do not interconvert and are therefore structural isomers rather than tautomers. These compounds themselves are rarely synthesized and have no particular utility, however, compounds that use them as structural motifs are fairly common in pharmacology.