製品名:6-Methyl-2,3,4,9-tetrahydro-1H-carbazole

IUPAC Name:6-methyl-2,3,4,9-tetrahydro-1H-carbazole

CAS番号:17177-17-2
分子式:C13H15N
純度:95%+
カタログ番号:CM369037
分子量:185.27

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製品詳細

CAS番号:17177-17-2
分子式:C13H15N
融点:-
SMILESコード:CC1=CC2=C(NC3=C2CCCC3)C=C1
密度:
カタログ番号:CM369037
分子量:185.27
沸点:
MDL番号:
保管方法:

Category Infos

Carbazoles
Carbazoles are an important class of nitrogen-containing heterocycles with a planar tricyclic skeleton consisting of two benzene rings fused on both sides of the central pyrrole ring, with a large aromatic system and a central nitrogen atom, showing broad of electron delocalization. The structure of this compound is based on the indole structure, but in which a second benzene ring is fused to a five-membered ring at positions 2-3 of the indole. Carbazole structural motifs are widely found in, but not limited to, a large number of natural alkaloids of plant or bacterial origin. Since many of these alkaloids are medically useful, exhibit a fairly wide range of biological activities (anticancer, anti-HIV, antibacterial, anti-Alzheimer's disease, anticoagulant, analgesic, antiepileptic, antidiabetic, antioxidant, etc.). Medicinal chemistry also uses carbazole motifs in synthetic drugs to combat hypertension, heart disease, and hepatitis C virus replication.
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Product Other Information

Product Overview 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole, also known as MTHC, is a heterocyclic compound with a carbazole backbone.
Synthesis Method 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole can be synthesized by the Pictet-Spengler reaction, which involves the condensation of an indole or tryptamine with an aldehyde or ketone in the presence of an acid catalyst.
Chemical Properties 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole is challenging to synthesize and is unstable under certain conditions, which limits its use in laboratory experiments.
Synthesis and Application 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole has been studied for its potential therapeutic applications in the treatment of obesity, depression, and anxiety disorders. In animal models, 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole has been shown to reduce food intake and body weight by activating the 5-HT2C receptor, which regulates satiety and energy balance. 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole has also been shown to have antidepressant and anxiolytic effects by modulating the serotonergic system in the brain.
Future Directions Future directions for research on 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole include the development of more efficient synthesis methods, the investigation of its potential therapeutic applications in humans, and the exploration of its interactions with other neurotransmitter systems. 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole may also have potential applications in the treatment of cognitive disorders such as Alzheimer's disease and schizophrenia. Further research is needed to fully understand the mechanism of action and potential therapeutic benefits of 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole.