製品名:3-(2,4-difluorophenyl)-1-methyl-N-(2-{8-methylimidazo[1,2-a]pyridin-2-yl}phenyl)-1H-pyrazole-5-carboxamide

IUPAC Name:3-(2,4-difluorophenyl)-1-methyl-N-(2-{8-methylimidazo[1,2-a]pyridin-2-yl}phenyl)-1H-pyrazole-5-carboxamide

CAS番号:1788948-92-4
分子式:C25H19F2N5O
純度:95%+
カタログ番号:CM851001
分子量:443.46

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製品詳細

CAS番号:1788948-92-4
分子式:C25H19F2N5O
融点:-
SMILESコード:CN1N=C(C=C1C(=O)NC1=C(C=CC=C1)C1=CN2C=CC=C(C)C2=N1)C1=C(F)C=C(F)C=C1
密度:
カタログ番号:CM851001
分子量:443.46
沸点:
MDL番号:
保管方法:

Category Infos

Pyrazoles
Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.
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Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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