製品名:5-((Benzyloxy)carbonyl)-5-azaspiro[2.3]hexane-1-carboxylic acid

IUPAC Name:5-[(benzyloxy)carbonyl]-5-azaspiro[2.3]hexane-1-carboxylic acid

CAS番号:1820619-57-5
分子式:C14H15NO4
純度:95%+
カタログ番号:CM212194
分子量:261.28

包装単位 有効在庫 価格(USD) 数量
CM212194-100mg in stock Źƥƥ
CM212194-250mg in stock ůNJǵ

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製品詳細

CAS番号:1820619-57-5
分子式:C14H15NO4
融点:-
SMILESコード:O=C(C1CC12CN(C(OCC3=CC=CC=C3)=O)C2)O
密度:
カタログ番号:CM212194
分子量:261.28
沸点:
MDL番号:MFCD26407047
保管方法:

Category Infos

Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

Benzenes
Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.

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