製品名:1,2-O-Isopropylidene-D-glucofuranose
IUPAC Name:(1R)-1-[(3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol
Product Overview |
1,2-O-Isopropylidene-D-glucofuranose (IPG) is a sugar derivative that has been used in scientific research for a variety of purposes. IPG is a valuable tool for scientists due to its ability to serve as a substrate for enzyme-catalyzed reactions, as a chiral selector in chromatographic separations, and as a ligand for protein binding studies. |
Synthesis and Application |
1,2-O-Isopropylidene-D-glucofuranose can be synthesized in a two-step process using the acetalization of D-glucose. The first step involves the reaction of D-glucose with di-tert-butyl dicarbonate in the presence of triethylamine, which yields the acetal intermediate. The second step involves the reaction of the acetal intermediate with isopropyl bromide in the presence of a base, yielding 1,2-O-Isopropylidene-D-glucofuranose. 1,2-O-Isopropylidene-D-glucofuranose has been used in a variety of scientific research applications. It has been used as a chiral selector in chromatographic separations, as a substrate for enzyme-catalyzed reactions, and as a ligand for protein binding studies. It has also been used to study the effects of chirality on enzyme activity, to study the effects of chirality on protein-ligand interactions, and to study the effects of chirality on drug metabolism. |
Future Directions |
There are several potential future directions for 1,2-O-Isopropylidene-D-glucofuranose research. These include further research into the effects of 1,2-O-Isopropylidene-D-glucofuranose on enzyme activity, protein-ligand interactions, and drug metabolism. Additionally, further research into the potential therapeutic applications of 1,2-O-Isopropylidene-D-glucofuranose is warranted. Finally, further research into the use of 1,2-O-Isopropylidene-D-glucofuranose as a chiral selector in chromatographic separations is also needed. chemenu website |