製品名:tert-Butyl 5-benzyl-octahydropyrrolo-[3,4-c]pyrrole-2-carboxylate

IUPAC Name:tert-butyl 5-benzyl-octahydropyrrolo[3,4-c]pyrrole-2-carboxylate

CAS番号:186202-73-3
分子式:C18H26N2O2
純度:97%
カタログ番号:CM197623
分子量:302.42

包装単位 有効在庫 価格(USD) 数量
CM197623-250mg in stock ʼnƥ
CM197623-1g in stock ŹŗNJ

研究開発用専用.

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製品詳細

CAS番号:186202-73-3
分子式:C18H26N2O2
融点:-
SMILESコード:O=C(N1CC(CN(CC2=CC=CC=C2)C3)C3C1)OC(C)(C)C
密度:
カタログ番号:CM197623
分子量:302.42
沸点:
MDL番号:MFCD18909636
保管方法:Store at 2-8°C.

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

Column Infos

Seltorexant
Johnson & Johnson pivotal study of Seltorexant shows statistically significant and clinically meaningful improvement in depressive symptoms and sleep disturbance outcomes. Seltorexant meets all primary and secondary endpoints in the pivotal Phase 3 MDD3001 clinical trial of adult and elderly patients with major depressive disorder (MDD) with insomnia symptoms.
Orexin signaling pathways are found to be associated with depression and anxiety. Orexin neurons receive and transmit signals throughout the central nervous system (CNS) that are modulated by their specific receptors (OX1R, OX2R). Seltorexant is an investigational first-in-class selective antagonist of ORX2 receptor. It is developed as an adjunctive therapy for MDD and for the treatment of insomnia disorder.

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