製品名:[4-(1,3-oxazol-5-yl)phenyl]methanamine hydrochloride

IUPAC Name:1-[4-(1,3-oxazol-5-yl)phenyl]methanamine hydrochloride

CAS番号:1909313-65-0
分子式:C10H11ClN2O
純度:95%+
カタログ番号:CM446732
分子量:210.66

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製品詳細

CAS番号:1909313-65-0
分子式:C10H11ClN2O
融点:-
SMILESコード:Cl.NCC1=CC=C(C=C1)C1=CN=CO1
密度:
カタログ番号:CM446732
分子量:210.66
沸点:
MDL番号:MFCD28384793
保管方法:

Category Infos

Oxazoles
Oxazoles are heterocyclic aromatic compounds containing one oxygen atom and one nitrogen atom, separated by a carbon atom. The presence of two heteroatoms (oxygen and nitrogen) provides possible interactions (hydrogen, hydrophobic, van der Waals or dipole bonds) with a wide range of receptors and enzymes. Oxazole rings are valuable heterocyclic scaffolds for the design of novel therapeutics with anticancer, antiviral, antibacterial, anti-inflammatory, neuroprotective, antidiabetic, and antidepressant properties due to their wide range of targets and biological activities.

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Product Other Information

Product Overview [4-(1,3-Oxazol-5-yl)phenyl]methanamine hydrochloride, also known as PBOX-15, is a novel compound that has gained significant attention in the field of medicinal chemistry due to its potential therapeutic applications. This compound is a derivative of 4-aminophenylmethanamine and contains an oxazole ring that enhances its pharmacological properties.
Synthesis Method The synthesis of [4-(1,3-Oxazol-5-yl)phenyl]methanamine hydrochloride involves the reaction of 4-aminophenylmethanamine with 5-chloro-1,3-oxazole in the presence of a base such as potassium carbonate. The resulting product is then purified using column chromatography to obtain the pure compound. This method has been optimized to yield high purity and high yield of the compound.
Physical Properties One limitation of using this compound is its relatively low solubility, which can make it difficult to work with in certain experiments.
Synthesis and Application It has been found to exhibit potent anticancer activity against various cancer cell lines, including breast cancer, lung cancer, and prostate cancer. It has also been shown to have anti-inflammatory and anti-angiogenic properties, making it a potential candidate for the treatment of inflammatory diseases and angiogenesis-related disorders.
Future Directions One area of interest is the development of more efficient synthesis methods to improve the yield and purity of the compound. Another area of focus is the elucidation of the compound's exact mechanism of action, which could lead to the development of more targeted and effective cancer therapies. Additionally, further studies are needed to explore the compound's potential applications in the treatment of other diseases, such as inflammatory disorders and angiogenesis-related disorders.