製品名:oxetane-3-sulfonyl fluoride

IUPAC Name:oxetane-3-sulfonyl fluoride

CAS番号:1934400-17-5
分子式:C3H5FO3S
純度:95%
カタログ番号:CM578032
分子量:140.13

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製品詳細

CAS番号:1934400-17-5
分子式:C3H5FO3S
融点:-
SMILESコード:C1C(CO1)S(=O)(=O)F
密度:
カタログ番号:CM578032
分子量:140.13
沸点:
MDL番号:
保管方法:Store at 2-8°C

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.
Thietanes
Thietanes are important structural motifs of some biological compounds and useful intermediates in organic synthesis.