製品名:tert-butyl 3-[(chlorosulfonyl)methyl]oxetane-3-carboxylate

IUPAC Name:tert-butyl 3-[(chlorosulfonyl)methyl]oxetane-3-carboxylate

CAS番号:1955519-85-3
分子式:C9H15ClO5S
純度:95%+
カタログ番号:CM389115
分子量:270.72

包装単位 有効在庫 価格(USD) 数量
CM389115-250mg in stock Əȋŭ
CM389115-500mg in stock ƅǠǺ
CM389115-1g in stock Ǻŭƻ

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製品詳細

CAS番号:1955519-85-3
分子式:C9H15ClO5S
融点:-
SMILESコード:CC(C)(C)OC(=O)C1(CS(Cl)(=O)=O)COC1
密度:
カタログ番号:CM389115
分子量:270.72
沸点:
MDL番号:
保管方法:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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