製品名:N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-5-yl]prop-2-enamide

IUPAC Name:N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]prop-2-enamide

CAS番号:1957235-53-8
分子式:C16H13N3O5
純度:95%
カタログ番号:CM1076169
分子量:327.3

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製品詳細

CAS番号:1957235-53-8
分子式:C16H13N3O5
融点:-
SMILESコード:C=CC(=O)NC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1
密度:
カタログ番号:CM1076169
分子量:327.3
沸点:
MDL番号:
保管方法:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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