製品名:2-Oxa-6-aza-spiro[3.3]heptanetosylate

IUPAC Name:2-oxa-6-azaspiro[3.3]heptan-1-yl 4-methylbenzene-1-sulfonate

CAS番号:2083631-41-6
分子式:C12H15NO4S
純度:95%+
カタログ番号:CM622710
分子量:269.32

包装単位 有効在庫 価格(USD) 数量
CM622710-250mg in stock ƥȃʼn
CM622710-500mg in stock ƥƥŹ
CM622710-1g in stock ƥŗǵ
CM622710-5g in stock ůŹŹ
CM622710-25g in stock ƥǵŹŹ

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製品詳細

CAS番号:2083631-41-6
分子式:C12H15NO4S
融点:-
SMILESコード:CC1=CC=C(C=C1)S(=O)(=O)OC1OCC11CNC1
密度:
カタログ番号:CM622710
分子量:269.32
沸点:
MDL番号:MFCD31556364
保管方法:

Category Infos

Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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