製品名:4-bromo-6-(trifluoromethyl)indolin-2-one

IUPAC Name:4-bromo-6-(trifluoromethyl)-2,3-dihydro-1H-indol-2-one

CAS番号:2091064-29-6
分子式:C9H5BrF3NO
純度:95%+
カタログ番号:CM1017924
分子量:280.04

包装単位 有効在庫 価格(USD) 数量
CM1017924-250mg in stock NJưƄ
CM1017924-500mg in stock ȎNJƄ
CM1017924-1g in stock ŢȎǵ
CM1017924-5g 1-2 Weeks ʼnƞʼnƞ
CM1017924-10g 1-2 Weeks Ľʼnƞź

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製品詳細

CAS番号:2091064-29-6
分子式:C9H5BrF3NO
融点:-
SMILESコード:FC(F)(F)C1=CC(Br)=C2CC(=O)NC2=C1
密度:
カタログ番号:CM1017924
分子量:280.04
沸点:
MDL番号:
保管方法:

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Indolinones
Indolinone derivatives have in common the presence of a hydrogen bond between the C-2 carbonyl and a hydrogen donor in a side chain, generally a pyrrole ring. Indolinone displays very promising antitumor properties by inhibiting various kinase families.

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