製品名:1-(2-Pyrimidyl)piperazine

IUPAC Name:2-(piperazin-1-yl)pyrimidine

CAS番号:20980-22-7
分子式:C8H12N4
純度:97%
カタログ番号:CM121115
分子量:164.21

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製品詳細

CAS番号:20980-22-7
分子式:C8H12N4
融点:-
SMILESコード:N1(C2=NC=CC=N2)CCNCC1
密度:
カタログ番号:CM121115
分子量:164.21
沸点:
MDL番号:MFCD00040742
保管方法:

Category Infos

Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

Gepirone
The novel medication for the treatment of adults with major depressive disorder (MDD), Gepirone has eventually been approved by the FDA in late September following a long quest. Geprione belongs to the azapirone group, as the same class as buspirone. Gepirone acts as a full agonist at serotonin 5-HT1A autoreceptors and is generally, a partial agonist at postsynaptic serotonin 5-HT1A receptors. Gepirone has a unique antidepressant effect that relieves depressive symptoms without significant side effects.