製品名:2-(2,6-dioxopiperidin-3-yl)-4-prop-2-ynoxyisoindole-1,3-dione

IUPAC Name:2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)-2,3-dihydro-1H-isoindole-1,3-dione

CAS番号:2098487-39-7
分子式:C16H12N2O5
純度:95%+
カタログ番号:CM338818
分子量:312.28

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CM338818-10mg 3-4 Weeks ȤȤƚ

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製品詳細

CAS番号:2098487-39-7
分子式:C16H12N2O5
融点:-
SMILESコード:O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCC#C)=O
密度:
カタログ番号:CM338818
分子量:312.28
沸点:
MDL番号:
保管方法:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.