cas 211814-16-3|| where to buy N-cyclopropyltetrahydro-2H-pyran-4-amine

製品名:N-cyclopropyltetrahydro-2H-pyran-4-amine

IUPAC Name:N-cyclopropyloxan-4-amine

包装単位	有効在庫	価格（USD）
CM115799-1g	in stock	ǫŪ
CM115799-5g	in stock	ƐƐǫ

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: CAS番号:211814-16-3; 分子式:C8H15NO; 融点:-; SMILESコード:C1(NC2CC2)CCOCC1; 密度:

: カタログ番号:CM115799; 分子量:141.21; 沸点:; MDL番号:MFCD10568362; 保管方法:Store at 2-8°C.

: Cyclopropanes; Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

: Tetrahydropyrans; Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.

: Pyrans; Pyrans are an important class of six-membered heterocyclic compounds, non-aromatic rings, composed of five carbon atoms and one oxygen atom, and contain two double bonds. The molecular formula of pyran is C5H6O, and there are two isomers. Pyrans, together with benzo derivatives, form scaffolds for a variety of drug applications, many of which are approved and promising candidates in clinical trials and recently isolated bioactive natural products.