cas 2178991-05-2|| where to buy 1-(6-(2H-1,2,3-Triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl)-3-(7-(cyclopropyl(dimethylamino)methyl)-2-methylthiazolo[5,4-b]pyridin-6-yl)urea

製品名:1-(6-(2H-1,2,3-Triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl)-3-(7-(cyclopropyl(dimethylamino)methyl)-2-methylthiazolo[5,4-b]pyridin-6-yl)urea

IUPAC Name:3-{7-[cyclopropyl(dimethylamino)methyl]-2-methyl-[1,3]thiazolo[5,4-b]pyridin-6-yl}-1-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea

: CAS番号：2178991-05-2; 分子式：C22H22F3N9OS; 純度：95%+

: カタログ番号：CM558548; 分子量：517.54

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: CAS番号:2178991-05-2; 分子式:C22H22F3N9OS; 融点:-; SMILESコード:O=C(NC1=CC(C(F)(F)F)=C(N2N=CC=N2)N=C1)NC3=CN=C(SC(C)=N4)C4=C3C(C5CC5)N(C)C; 密度:

: カタログ番号:CM558548; 分子量:517.54; 沸点:; MDL番号:; 保管方法:

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: Cyclopropanes; Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

: Thiazolopyridines; Thiazolopyridines are a class of heterocyclic compounds. Thiazolopyridines were developed as allosteric inhibitors of MALT1 with good cellular potency and refined selectivity.

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